Research works

Persistent Redox Imbalance in Post-COVID-19 Syndrome: Lipid Peroxidation, Antioxidant Enzyme Depletion, and Reduced Nitric Oxide Availability in an Amazonian Population

Post-COVID-19 syndrome (PCS) can persist even after mild acute illness, and oxidative stress has been proposed as a central mechanism for this persistence, although it remains poorly studied in the Amazon. This study characterized redox imbalance in patients with PCS through a co...

The Undiscovered Human: A Philosophical Essay on the Hidden Taxonomy of Human Capacities

This essay argues that contemporary psychology is in its pre-Mendeleev phase: the human traits we recognize today — intelligence, creativity, empathy — are not the fundamental building blocks of the person, but merely the traits that happened to be visible to twentieth-century in...

Dental Care as a Test Case for Rural Health Reform

This Viewpoint uses dental care as a test case for whether rural health care reform translates into more reliable access.

STING‑regulated Ca²⁺–TGF‑β axis drives airway remodeling and lung function decline in asthma: a multi‑omics mechanistic study

The progressive lung function decline in severe asthma is poorly explained by traditional inflammation‑centered paradigms. Calcium (Ca²⁺) dysregulation and transforming growth factor‑β (TGF‑β) signaling have been implicated, but the molecular link between them and their upstream...

First Detection and Seasonal Dynamics of Proliferative Kidney Disease in Northwestern Italy

Proliferative kidney disease (PKD), caused by the myxozoan parasite Tetracapsuloides bryosalmonae, represents a major threat to salmonid populations and aquaculture, particularly under warming environmental conditions. In Italy, its distribution remains poorly documented. This st...

Nanoscale Transdermal Drug Delivery Systems for Osteoarthritis: Strategies to Overcome the Skin Barrier

Abstract Osteoarthritis (OA) is a long-term degenerative common complaint characterized by increasingjoint dysfunction, synovial inflammation, and cartilage degradation. While traditionaltherapies, such as oral non-steroidal anti-inflammatory medicines (NSAIDs) and intra-articula...

EuroMillions Breakthrough Mining — 1815 Sources, 13652 Leads Extracted — E8 Intelligence Research

Mined 1815 lottery+quantum breakthroughs. Extracted 13652 leads across 13 categories. 11645 high-value leads found. Categories: {"CORRIDOR": 1139, "FORMULA": 981, "GEOMETRIC": 727, "FORWARD_ATTEMPT": 1192, "QUANTUM": 1407, "TIMING": 208, "CELESTIAL": 1067, "GEMATRIA": 1138, "CONS...

How does advertising goal framing impact green hotel consumption intentions? The moderating role of nature connectedness

Promoting green hotel consumption is a key element in the green transformation and upgrading of the tourism industry. Goal framing serves as a common method of information presentation to encourage consumer behavior. However, few studies have examined how advertising goal framing...

A New Extinct Genus of Zingiberales From the Early Paleogene of India and Insights Into the Parallel Dynamics of Extinction and Diversification of the Monocot Order

ABSTRACT The fossil record serves as the primary source of information for understanding how biodiversity has changed over deep time, offering unique insights into the dynamics of diversification and extinction and their underlying drivers. Much of the focus has been on global di...

Prospective comparative evaluation of povidone-iodine sitz bath and silver-based antimicrobial spray in postoperative perianal wound care: impact on healing outcomes, patient satisfaction, and treatment compliance

Perianal surgical wounds are likely to take longer to heal and get infected due to constant contamination, moisture and pain during defecation. Povidone-iodine has long been applied in the postoperative treatment, and silver-based agents have become an alternative with an excelle...

Life cycle and behavioral analysis of single-use research laboratory plastic recycling on a college campus

Purpose University research laboratories generate large volumes of single-use plastics, particularly polypropylene (PP) research waste (e.g. pipette tips). While reduction and reuse strategies remain the preferred actions within the circular economy hierarchy (e.g. 10R/3R: reduce...

Influence of many-body correlation and mixed-valence fluctuations on X-ray magnetic circular dichroism and resonant inelastic X-ray scattering spectra

X-ray magnetic circular dichroism (XMCD) and resonant inelastic X-ray scattering with magnetic circular dichroism (RIXS-MCD) provide unparalleled insights into the electronic and magnetic dynamics of complex materials. However, interpreting their spectra in mixed-valence systems...

Inflammation, Statin Pleiotropy, and Cardiovascular Prevention in Women: Established Evidence, Biological Plausibility, and Knowledge Gaps

Cardiovascular disease remains the leading cause of death among women, yet female cardiovascular risk continues to be underrecognized, and women remain underrepresented in many cardiovascular trials. Sex-related differences in hormonal exposure, immune regulation, vascular functi...

PFUSRC-154 Unified Topological Interpretation of Extreme Cosmic Phenomena in the Topological Mother Universe ——and the Isomorphic Overflow Effect at Black Hole Sub-Universe Boundaries

A wide range of extreme cosmic phenomena such as black holes, magnetars, gamma-ray bursts, quasars, cosmic voids and cold spots can only be fragmentarily explained by general relativity, quantum field theory and the ΛCDM model without a unified ontological foundation. Relying on...

UnravelingSulfur Vacancy Evolution Mechanism duringLow-Temperature H2 and S Vapor Annealing in Monolayer Mo(1– x )W x S2 Alloys

Abstract This study systematically modulated the healing and creation of S vacancies in monolayer Mo(1–x)WxS2 alloys via low-temperature H2 and S vapor annealing, observing three distinct types of photoluminescence (PL) evolutions. Type I featured intensified PL, a decreased X–/X...

Matter and Antimatter: The Mirror-Flow Model

An accounting model derives the matter–antimatter asymmetry without symmetry breaking, from four assumptions: three axes with two directions each; doubling; unbreakable mirror symmetry; and the rule of existence — nothing exists without completing its cycle. The antiparticle is t...

Paternal Exposure to Endocrine Disrupting Chemicals and Couples’ Pregnancy Outcomes: A Qualitative Review of the Literature

Abstract Purpose of Review Endocrine-disrupting chemicals (EDCs) are ubiquitous, and exposure to them has been associated with adverse reproductive health in both animals and humans. While the adverse effects of maternal EDC exposures on pregnancy outcomes have been extensively i...

THE REALITY OF EXISTENCE | حقيقة الوجود والمعنى — Why Anything Exists at All — Institutional Research & Book Framework Edition

THE REALITY OF EXISTENCE | حقيقة الوجود والمعنى by Syed Raheel Shahzad is Stage 0 of The Source of Truth System™ and the foundation on which every later question in the system depends. The work begins before doctrinal commitment and asks whether existence itself can be treated as...

Cell Painting in activated cells illuminates phenotypic dark space and drug mechanisms of action

Abstract As drug and natural product libraries expand, assays for assessing mechanisms of action (MoA) are increasingly critical. Performing cytological profiling using the Cell Painting (CP) assay enables image-based profiling of cellular states upon treatment, yet many bioactiv...

Warm Acclimation Modulates the Physiological Responses of Young Saccharina japonica to Marine Heatwaves

Frequent marine heatwaves (MHWs) pose significant threats to and have a profound impact on the structure and functioning of marine ecosystems. The response of marine organisms to MHWs may depend on the background temperature of their habitats. Saccharina japonica is a cold-temper...