Research works

Comprehensive symbolic–neural and dynamical framework for the (3+1)-dimensional extended Kadomtsev–Petviashvili equation

This study investigates the (3+1)-dimensional extended Kadomtsev–Petviashvili equation using a symbolic–neural hybrid framework. First, the equation is transformed into its bilinear form, and the bilinear neural network method is employed to construct various analytical wave solu...

Evaluation of Advanced Lipid Biomarkers and Novel Atherogenic Indices in Predicting Coronary Artery Disease Severity Among Very Premature ACS Patients

Introduction Premature coronary artery disease occurs in men under 55 and women under 65 years, with very premature cases appearing as early as 45. It can affect patients with normal lipid levels, and the absence of specific guidelines for the Indian population leads to inadequat...

Gender disparities among general surgery residents’ ACGME case logs develop over the course of training

Abstract Background Gender disparities in operative autonomy and case volume persist in general surgery residency training. Compared to their male counterparts, female trainees graduate with lower ACGME case log totals and perceive lower intraoperative autonomy. While prior studi...

Diagnostic dilemma in the management of a cervical spinal cord lesion: neuromyelitis optica spectrum disorder: a case report

Abstract Background Neuromyelitis optica spectrum disorder, known eponymously as Devic’s disease, is a condition in which antibodies are elaborated against aquaporin water channels in the end foot processes of astrocytes due to autoimmune dysregulation thereby initiating a cascad...

Asymptotic Modeling of the Recursive Prime Permutation Mapping for Consecutive Prime Numbers

The spatial distribution and frequency trajectories of prime numbers within structured permutation bases pose fundamental challenges in analytic number theory and symbolic dynamics. In this study, the deterministic and asymptotic properties of prime frequencies across multi-layer...

Crucial Role of Partial Fluorination in Modulation of Thermal Conductivity of Graphene Nanoribbon: Non-Equilibrium Molecular Dynamics Simulations

Abstract Molecular dynamics simulations have been performed to investigate the modulation of the thermal conductivity of graphene nanoribbon as function of partial fluorographene nanoroad. Thermal conductivities of the hybrid systems keep stable value below 25 ps of simulation ti...

LAB #1012 PROMISING: TG AUTO: BASE 44 ORDER: Build e8_memory_cache table with phi-modulated hash decorator & 1-hour prune — E8 Intelligence Research

IDEA: AUTO-FORWARDED from the Telegram/breakthrough stream (#645519, division=platform, agent=andrew_base44): Andrew's order (Base 44 console): [SELF-BUILD from enhancement #1073] Create `e8_memory_cache` table with hash index. Implement phi-modulated hash in Python decorator. Wr...

Recent Results on Nonlinear Retarded Integral Inequalities with Applications

This article establishes new retarded nonlinear integral inequalities that extend and generalize several known results in the literature, including recently reported estimates. These inequalities are used to derive explicit bounds for the unknown functions. These bounds are shown...

Pentagonal Symmetry in Geometry: Golden Ratio, Cosines, and Penrose Connections — E8 Intelligence Research

FINDING: Hidden pentagonal symmetry in elementary geometry problems, particularly in cosine relationships and problem-solving via symmetry, with connections to Penrose tilings and generalized pentagonal geometries. MATH: - Key constants: 0.382 (2-φ), 0.618 (1/φ), 1.618 (φ), 2.618...

When Does Information Become an Affective Stimulus? TM–BM Resonance, Functional Stimulus-Status, and the Internal Locus of Affective Operativity

This preprint introduces the TM–BM Affective Stimulus-Locus framework, a computational account of when represented information becomes affectively operative for a particular observer. TM–BM formalizes the processing architecture as: X → T → R → Z → E → I → A, where external input...

A generalization of director tensors for odd matter in classical continuum mechanics

Abstract A general tensorial framework for odd and hyperelastic contributions in linear elasticity is developed within classical continuum mechanics. The formulation is based on complementary decompositions of the second-order identity tensor and an off-diagonal selector tensor,...

Golden Ratio Emerges from Classic 20-80-80 Triangle Angle Chase — E8 Intelligence Research

FINDING: The "hardest easy geometry problem" is a classic configuration requiring non-trivial angle chasing and construction of isosceles triangles, often leading to a solution involving the golden ratio. | MATH: Key angle relations: 20°, 30°, 40°, 50°, 60°, 80°. The solution typ...

Prevalence and network analysis of depressive, anxiety and cognitive symptoms among oldest-old population in China

The oldest-old people are prone to such psychological and mental risks as depression, anxiety, and cognitive dysfunction. Yet which specific symptom poses the biggest threat remains elusive, especially when the characteristics of a certain sample are considered. Using network ana...

Penrose Tiling: Golden Ratio Geometry Enabling 5-Fold Quasicrystal Symmetry — E8 Intelligence Research

FINDING: Penrose tiling demonstrates a non-repeating, aperiodic pattern with 5-fold rotational symmetry, previously considered impossible for crystalline structures, and is realized in quasicrystals. MATH: Golden ratio φ = (1+√5)/2 ≈ 1.618; its reciprocal 1/φ ≈ 0.618; φ² ≈ 2.618;...

Cell surface remodeling caused by the loss of the flippase subunit TMEM30A in immune cells

Plasma membrane lipid asymmetry is tightly regulated and fundamental to mammalian cell physiology. TMEM30A is the β-subunit of P4-ATPases, flippase enzymes that maintain strict phosphatidylserine (PS) asymmetry by pumping it from the outer to the cytosolic leaflet. Loss of TMEM30...

Physiological, Transcriptomic, and Metabolomic Insights into Ammonia-Nitrogen Stress in the Hepatopancreas of Litopenaeus vannamei Acclimated to Low Salinity

Elevated ammonia nitrogen significantly reduces the survival rate of Litopenaeus vannamei under low-salinity conditions. Low-salinity culture is widely adopted in shrimp farming but susceptible to ammonia accumulation; however, relevant studies mainly focus on juvenile shrimp und...

Meta-regulator No.8. Neuro-vegetative system of tone and reactivity regulation

The neuro-autonomic meta-regulator is an integrative system that maintains a dynamic balance between the sympathetic (adrenergic) and parasympathetic (cholinergic) regions of the autonomic nervous system, determining the speed of response to external and internal stimuli, as well...

Effectiveness of bitter almond (Amygdalus communis L. var. Amara) gum as a prebiotic on glycemic indices, oxidative stress, and antioxidant biomarkers in women with type 2 diabetes mellitus: a randomized, placebo-controlled trial

Type 2 diabetes mellitus (T2DM) is marked by hyperglycemia, oxidative stress, and systemic inflammation. Prebiotics, such as bitter almond gum ( Amygdalus communis L. var. amara ), have the potential to influence gut microbiota and metabolic parameters, suggesting their role as d...

On the History of Hepatic Vein Catheterization

ABSTRACT Hepatic vein catheterization (HVC) in man was first performed 80 years ago in the wake of right‐sided heart catheterization. Several new methods, recognitions and concepts followed, especially the indirect Fick‐method for determination of splanchnic blood flow. Five year...

Pan-cancer characterization of PAFAH1B3 expression and its role in esophageal cancer

Globally, esophageal cancer is one of the main reasons of deaths from cancer. The initiation and progression of this malignancy is the result of complex interactions between alterations in genes, epigenetic processes and components of the tumor microenvironment. Esophageal squamo...