Research works

Idiopathic Tinnitus: A Testable Bio-Electronic Behavioral Analogy — The Wave-Interference Interpretation of Tinnitus (WIIT)

Idiopathic tinnitus—subjective, audiogram-independent, without an identified medical etiology—remains without a satisfying explanatory account for a substantial subset of cases, and no directly comparable methodological precedent linking such presentations to documented interfere...

Observational Evidence for PPL Space: Decisive Statistical Validation of the 4/3 Critical Clamping Phenomenon in GWTC-3

We present a decisive statistical analysis of gravitational wave events from the GWTC-3 catalog to test the predictions of the PPL space model against standard General Relativity (GR). While GR predicts a continuous inspiral-merger-ringdown waveform with a smooth amplitude peak,...

Physiological Response and Nutrient Uptake (N,P,K) of Edamame Soybeans under Different Types and Rates of Sago Waste Biochar in Aluvial Soil

Edamame soybeans grow optimally in tropical and subtropical climates with relatively high temperatures and adequate rainfall, making them suitable for cultivation in Indonesia. This study aimed to evaluate the interaction between the type and application rate of sago waste biocha...

Cosmochrony: A Non-Injective Projection Theory of Emergent Physics

Cosmochrony is a pre-geometric relational framework that does not replace quantum mechanics or general relativity, but operates at a deeper structural level from which both emerge as effective descriptions in appropriate regimes. Its aim is to expose the common infra-physical fou...

Global inequitable distribution of seminal studies of chemotherapy-induced nausea and vomiting

BACKGROUND: Chemotherapy-induced nausea and vomiting (CINV) remains one of the most quality of life limiting toxicities of cancer therapy. Decades of trials have produced robust antiemetic evidence, but their applicability to resource-limited settings where guideline-recommended...

Perioperative esketamine and postoperative sleep quality: a systematic review and meta-analysis of randomized trials

Abstract Background Postoperative sleep disturbance (PSD) is common among surgical patients and adversely affects recovery. The benefits of perioperative esketamine on sleep remain incompletely defined. Methods Randomized controlled trials (RCTs) comparing ketamine or esketamine...

Irreversible Foreclosure and the Allocation of Justificatory Burden in Governance beyond Epistemic Reach

Governance of the relations between human activity and the wider natural and cosmic field operates under a scale relation that the governance of human affairs has generally been spared. The field within which the relations obtain substantially exceeds both the portion of it that...

Therapeutic potential of dental follicle-derived stem cells and gold nanoparticles on osteoarthritic temporomandibular joint in guinea pigs (randomized prospective study)

Abstract Background Osteoarthritis (OA) is a complicated autoimmune disease that often causes invasive inflammatory infiltration and serious articular destruction. The global prevalence of temporomandibular disorders (TMDs) is estimated to be around 30% of the population. Several...

Governing Open Complex Giant Generative Relational Systems beyond Representation and Reach: A Synoptic Discussion of Systems, Scales, and Arrangements

Three companion papers establish results about the governance of systems that exceed what any party can represent or reach, and a fourth constitutes the class of problems such systems present. This paper adds the survey of the systems themselves that the four leave to be made. It...

Nickel-CatalyzedAsymmetric C(sp2)–PCoupling for the Direct Synthesis of the PMOP Atropisomeric PhosphineLigand

Abstract An efficient kinetic resolution of binaphthyl triflates is developed via Ni-catalyzed asymmetric C(sp2)–P cross-coupling to access substituted atropisomeric phosphines. Moreover, the phosphine framework showed superior reactivity and enantiocontrol in Pd-catalyzed asymme...

Federated Edge-HPC Architectures for AI Workflows in Privacy-Sensitive and Real-Time Domains – Final Report

This report presents the outcomes, technical evaluations, and roadmap recommendations of the “Federated Edge-HPC Architectures for AI Workflows in Privacy-Sensitive and Real-Time Domains” (FEDGE) project, funded by the UKRI National Federated Compute Services (NFCS) NetworkPlus.

HEDII and LESS: Heuristic Error Drift and the Sociology of Low-Energy Stabilization

This Perspective proposes a systems sociology explanation for the persistence of durable social hierarchies — including racism, sexism, and other forms of categorical stratification — under conditions of material abundance. Building on ESC/HSC (Live→Belong→Gather→See), HBC (PDS→S...

Prior Use and the Distribution of Observational Capacity in State-Dependent Governance

A governing rule whose content depends on the dynamical state of the system it governs requires that the state be determined. Where the system exhibits a critical value above which ordinary conduct produces irreversible foreclosure, the determination that the system has approache...

Electron-Donor–AcceptorEnabled ElectrophilicC(sp2)-C(sp3) Cross-Coupling

Abstract The construction of C(sp2)-C(sp3) bonds is fundamental to pharmaceutical synthesis, yet metal-free approaches to electrophilic cross-coupling remain underdeveloped. Herein, we report a visible-light-driven, metal-free cross-coupling between heteroaryl nitriles and alkyl...

Flood-related WASH disruption, point-of-use drinking water contamination and diarrhoea among under-five children in flood-affected communities in Ebonyi State, Nigeria

Abstract Background Flooding disrupts water, sanitation and hygiene (WASH) systems, increasing the risk of waterborne diseases among young children. This study examined the relationships between flood-related WASH disruption, drinking water contamination and diarrhoea among under...

2-Bayesian Update as Homotopy Pushout in the Derived Category of 𝐷 𝑋

We study the update of Bayesian update maps (2-Bayesian update) by formulating update maps as morphisms in the derived category Db(DX). We show that deformations of update maps are classified by Ext1 and that the universal synthesis of multiple update maps is given by the homotop...

Truly Cold Blooded: Year-round, Outdoor Keeping of Eastern Blue-Tongued Skinks (Tiliqua scincoides scincoides) in The UK

Blue-tongued skinks (genus Tiliqua) have always been a global ‘staple’ of the herpetological scene, due in no small part totheir size, docile nature, and relative ease of care. Here in the UK, the two captive-bred species most commonly encountered are Tiliqua gigas (Schneider, 18...

Double in Trouble: Facilitating the Rescue of Two of Africa's Most Threatened Amphibians

The Atewa Slippery Frog (Conraua sagyimase Neira-Salamea, Ofori-Boateng, Kouamé, Blackburn, Segniagbeto, Hillers, Barej, Leaché & Rödel, 2021) and Afia Birago's Puddle Frog (Phrynobatrachus afiabirago Ofori-Boateng, Leaché, Obeng-Kankam, Kouamé, Hillers & Rödel, 2018) are two cri...

A transformer-based framework for device-free human activity recognition using Wi-Fi CSI

Abstract Human activity recognition (HAR) plays a pivotal role in ambient assisted living, particularly for monitoring the elderly and patients with chronic conditions. However, traditional approaches relying on wearable sensors or video cameras face significant challenges regard...

HBC — Human Behavior Cycle: PDS → SDP → ERS: A 3-Stage Safety-First Model for Human Adaptation Under Enclosure (Perspective)

Traditional psychology treats symptoms as defects in the individual. The Human Behavior Cycle (HBC) proposes: Perceived Deficiency Signal (PDS) → Survival-Driven Pattern (SDP) → Externalized Response to Survival (ERS). PDS is a learned early alert that Belong and Gather are unpre...