Research works

ConSolv: Solvent-Conditional Machine Learning Implicit Solvent Potential

Abstract Implicit solvent machine learning potentials (MLPs) offer a powerful route to bridging the gap between accuracy and efficiency in molecular simulations. However, existing models have largely focused on aqueous environments, overlooking the diverse and important roles of...

CHEX-MATE: AMALGAM weak-lensing analysis of 41 Planck Sunyaev--Zel'dovich-selected galaxy clusters

We present a weak-lensing shear analysis of 41 =3.53 Sunyaev--Zel'dovich (SZ)-selected galaxy clusters at 0.11 łe z łe 0.55 from the CHEX-MATE sample, using wide-field Subaru/Suprime-Cam and CFHT/MegaPrime imaging from the project. The azimuthally averaged weak-lensing signal, me...

Multifunctional imaging with an inverse-designed non-local metasurface

Nonlocal metasurfaces enable all-optical processing of spatial information in optical fields. Here, we demonstrate a topology-optimised metasurface that switches between phase-contrast and brightfield imaging modalities via polarisation control, eliminating the need to reposition...

Context-aware optimization of follow-up intervals for type 2 diabetes care using Markov decision processes

Chronic disease management relies on regular patient-provider interactions to monitor progression and control. For type 2 diabetes (T2D), current guidelines prescribe fixed intervals between primary care visits, overlooking heterogeneity in clinical trajectories and patient chara...

Joint Modeling of GD-1 and C-19 as Old Streams

Abstract DESI observational data for the GD-1 and C-19 streams are compared to stream simulations in an evolving multihalo potential of a Milky Way–like galaxy based on a cosmological Milky Way–like simulation. The number of subhalos decreases with time, and the subhalo-stream en...

A Betchov-type hydrodynamic formulation of the Ivancevic option-pricing equation

We show that, under constant-coefficient assumptions, the Ivancevic option-pricing nonlinear Schrödinger equation admits a Betchov-type hydrodynamic formulation analogous to the one arising in the context of the vortex filament equation. Along with this structural correspondence,...

A coupled finite element formulation for chemo-mechano-thermo- dynamical contact and its application to bonding and debonding

This work presents a finite element formulation for coupled chemo-mechano-thermodynamical large deformation contact. The formulation is based on the contact theory of Sauer et al. (2022) that contains six coupled (but separate) fields: the deformation and temperature of the two c...

Non-linear mechanical field reconstruction coupling recurrent neural networks with physics-informed graph neural networks

Reconstructing local stress fields in heterogeneous microstructures under non-linear, history-dependent loading remains a major computational bottleneck in multi-scale simulations. We propose a coupled LSTM-GNN framework that links the temporal and spatial aspects of local stress...

Resolution Dependence of the Climate Feedback Parameter in Km‐Scale Climate Models

Abstract Global storm‐resolving models (GSRMs) provide new opportunities to investigate the climate response to warming with explicitly resolved deep convection. However, the limited number of existing studies has so far precluded the systematic assessment of similarities and dif...

Fast Astronomical Transients in Archival Photographic Plates: Using optical aberrations as a tool for discerning real images, from plate artifacts

The detection of fast astronomical transients in photographic plates from the Palomar sky surveys conducted in the 1950s, was subject to the criticism that such transients could be just the effect of otherwise unaccounted for plate artifacts. In this paper, we show that transient...

Glycosylated Diarylmethyloxy-Triazines: Facile Synthesis and Aqueous Self-Assembly for Supramolecular Hydrogel Formation

Abstract Glycosylated self-assembling molecules enable the construction of nanostructures whose surfaces are decorated with saccharides under aqueous conditions, reminiscent of biological systems at both the molecular and cellular levels. Such glyco-nanostructures thus hold great...

Relationship between neonatal glutamine supplementation and amino acid profiles, protein synthesis in splanchnic tissues and the plasma metabolome in 5-day-old piglets with low birth weight

The incidence of low birthweight ( LBiW ) piglets, which show impaired growth compared to normal birthweight ( NBiW ) littermates, has increased with litter size. We previously reported that glutamine increased the bodyweight and plasma glutamine concentrations in LBiW piglets, w...

Progress toward a Better BOCS: Systematic Coarse-Graining with Local Density Potentials

Abstract We introduce version 5.0 of the bottom-up open-source coarse-graining software (BOCS) package. BOCS employs the force-matching variational principle to parametrize potentials for coarse-grained (CG) models directly from atomically detailed simulations. BOCS version 5.0 s...

Closed string trajectories from a new “tiling”

A bstract Based on an efficient technology for the excavation of entire open string trajectories of physical states, we propose an algorithmic method of constructing the largely unknown closed string trajectories. Due to combinatorial complexity, the “double copy” of open strings...

Path integral quantization of null bosonic strings with Carroll-Weyl ghosts

A bstract We revisit the path integral quantization of the null bosonic string from the viewpoint that all local gauge symmetries of the Carrollian worldsheet must be gauge fixed before the quantum theory is defined. In the tensile-string construction the bc ghosts are the Faddee...

Experimental Methods for CRISPR Enzyme Assays with Fluorescence Readout

Fluorescence-based CRISPR diagnostic assays have become a popular platform for nucleic acid detection due to their programmability, configurability, specificity, and compatibility with standard laboratory equipment. However, reported enzymatic kinetic rates and limits of detectio...

Finite Kleshchev Bipartitions and q-Trinomial Coefficients

Abstract The Kleshchev multipartitions arise from the representation theory of the Ariki–Koike algebras. In previous work, Li, Stanton, Xue, Yee, and the author considered a refined enumeration for the 2-dimensional case, namely, the Kleshchev bipartitions, by invoking the 2-resi...

Melt Production and Volatile Release From Thermochemical Mantle Plumes

Abstract Mantle plumes are thought to generate Large Igneous Provinces (LIPs), the largest outpourings of lava in the geologic record, which are associated with long‐lasting climatic warming events and mass extinctions. However, the controls on mantle degassing by plumes remain p...

Statistical properties of internal modulation in pulsating aurora

Abstract. We statistically investigated the occurrence characteristics of internal modulation (IM), a rapid intensity modulation of a few hertz embedded in pulsating aurora (PsA), using high-speed ground-based optical data obtained with qCMOS cameras. For datasets acquired at Kir...

Temperature sensitivity of snow viscoplasticity: Evidence from controlled creep experiments

Abstract. Snow is a warm, porous material whose densification under its own weight is highly temperature-dependent. Despite decades of research, reported activation energies for snow viscoplasticity remain highly scattered, ranging from 40 to 600 kJ mol-1. We quantified the tempe...