Research works

Facing uncertainty in primary care: perceptions, strategies and educational needs – a qualitative explorative study with German general practice trainees

Abstract Background Uncertainty is an inherent aspect of everyday practice in primary care with a context of low-prevalence conditions. Dealing with diagnostic ambiguity and therapeutic uncertainty constitutes a central challenge within postgraduate medical training in general pr...

Insomnia in medical students during an examination period: associations with depression, dysfunctional sleep beliefs, and academic performance

Abstract Background Insomnia is common among medical students and is linked to impaired mental health and academic functioning. Medical students are exposed to persistent psychosocial stress, yet the extent to which state factors (e.g., stress, mood) versus trait factors (e.g., c...

Effect of injectable platelet rich fibrin augmented with vitamin c compared to injectable platelet rich fibrin alone on healing of necrotic mature single rooted teeth with chronic periapical periodontitis following regenerative endodontic therapy (a randomized controlled trial)

OBJECTIVES: To assess the healing potential, postoperative pain and clinical normalcy associated with injectable platelet-rich fibrin combined with Vitamin C in regenerative endodontic procedure using cone-beam computed tomography and two-dimensional radiograph. METHODS: Twenty-e...

Defect-engineered Ce 3+ -doped borosilicate glass scintillator for multifunctional and environment-adaptive X-Ray imaging

Abstract Advanced scintillation materials capable of simultaneously delivering ultrahigh efficiency, exceptional stability, and multifunctional X-ray imaging remain elusive because of intrinsic trade-offs in conventional scintillators. Hernin, a defect-engineered Ce3+-activated b...

The Topos of Contested Price and Energy Security: A Sheaf-Theoretic Analysis of Bangladesh and the 2026 Hormuz Disruption

This paper provides a sheaf-theoretic and topos-theoretic analysis of global energy market fractures, focusing on the empirical case of Bangladesh during the 2026 Strait of Hormuz disruption. Classical economic models treat energy markets as unified probability spaces governed by...

From nutrient intake to socioeconomic factors: what shapes diet quality in pregnancy?

Abstract Background Optimising maternal diet quality is among the most promising targets for public health interventions to improve the health of current and future generations. The aim of this study was to assess the construct validity of the Canadian Pregnancy Diet Quality Inde...

Formal Recursive Layer Theory and the Generative Construction of Mathematical Structures

FRLT formalizes generation through informational, generative, and causal layers. Twist‑insertion integrates quaternion rotation, phase flow, and lemniscate geometry, producing structural pivots and unified groupoid dynamics. The framework constructs manifold formation and causal...

Intermediality beyond synchronisation: Text as a compositional agent in electroacoustic audiovisual performance

Abstract This paper examines how text can operate as an intermedial compositional agent in electroacoustic audiovisual performance. Through a focused practice-based case study of a single performance – F2 – in which electroacoustic sound, procedural visuals and projected and spok...

ARID1B promotes DNA end resection via MDC1 and co-transactivation of DNA repair genes with c-MYC in small cell lung cancer

Abstract AT-rich interactive domain-containing protein 1B (ARID1B) has been implicated in DNA damage repair; however, its precise molecular mechanisms and contributions to small cell lung cancer (SCLC) pathogenesis remain incompletely defined. In this study, analysis of clinical...

A Novel Framework for Smart Service Failure and Recovery

Abstract While conventional approaches to Service Failure and Recovery (SFR) predominantly rely on basic surveys and scenario-based experiments, recent advancements in failure recovery found in related fields like Industry 4.0, AI-enabled decision support and digital service syst...

Trifocal Geometry and Generative Stratification: An Axiomatic Framework for FRLT

Formal Recursive Layer Theory (FRLT) employs a triple-pivot scalar field Σ whose equal‑tension surfaces form asymmetric trifocal ovals, establishing a geometric basis for generative stratification and linking spatial structure with stability properties encoded in the Hessian of Σ...

A machine learning approach to predicting high-risk irritability trajectories across the transition to adolescence

Abstract Youth irritability, characterized as proneness to anger/frustration, is associated with negative mental health outcomes. This study identified irritability trajectories across the transition to early adolescence and applied machine learning to identify preadolescent pred...

Are Socioeconomic Status and Time in Preschool Mediators of Shared Environment Variance in Reading Ability?

While socioeconomic status (SES), time in preschool (TiP) and their interaction are related to reading ability, the results have been mixed. This study assessed whether the shared environment mediated these associations using a longitudinal behavior genetic design. Further, this...

Comparison of parental caregivers and associated factors with caregiver burden in rare paediatric diseases

Abstract Background Caregiving for children with rare diseases is associated with substantial psychosocial and practical burden, yet evidence on associated factors of caregiver burden across heterogeneous rare disease populations remains limited. Methods In this cross-sectional s...

Sr-anchoring-directed gradient shell architecture in Sr 2 Fe 1.5 Mo 0.5 O 6- δ cathodes for reversible protonic ceramic electrochemical cells

Abstract Strontium segregation remains a critical challenge for Sr-containing double perovskite cathodes, wherein outward-migrating Sr species accumulate at the surface and severely deteriorate interfacial electrochemical kinetics in reversible protonic ceramic electrochemical ce...

Upcycling Greenhouse Refrigerants into Sustainable Chemical Feedstocks

Abstract Rising global temperatures are driving demand for air conditioning, while leakage of high-GWP refrigerants further accelerates warming. In addition, the transition to low-GWP alternatives generates large volumes of waste refrigerants, which are currently treated by energ...

Constant Normalized Area in the Planar Three-Body Problem

We prove that a collision-free noncollinear planar Newtonian three-body motion with constant triangle area divided by barycentric moment of inertia is necessarily a Lagrange homographic motion. The masses are arbitrary positive numbers, and the conclusion holds on any open time i...

PSMα contributes to Egr1-dependent early neutrophil recruitment and host defense in a murine model of Staphylococcus aureus pneumonia

Abstract Background Staphylococcus aureus ( S. aureus ) pneumonia is associated with substantial morbidity and mortality. Neutrophils play a central role in host defense against bacterial infection and are significantly increased in the lungs during S. aureus pneumonia. However,...

Fare sensitivity at point zero: How fare-free transit riders react to fare reinstatement and service changes?

Abstract Transit users are considered insensitive to fare changes. Therefore, reducing fares is often viewed as ineffective for increasing ridership. However, removing fares has led to markedly different outcomes in practice. Fare-free transit (FFT) policies have resulted in subs...

Competing hysteresis mechanisms in HZO/MoS2 transistors with a metal–ferroelectric–metal–insulator–semiconductor gate stack

Ferroelectric field-effect transistors based on hafnium oxide offer a versatile platform for advanced memory concepts. Here, we demonstrate a proof-of-concept top-gated Hf0.5Zr0.5O2-based transistor integrating a metal–ferroelectric–metal–insulator–semiconductor (MFMIS) gate stac...