Research works
The research papers we track — the newest first. Works with a plain-language summary link to it.
128627 work(s)
- Health & MedicineOpen access
Cardiac arrhythmia, characterized by abnormal heart rhythms, can be effectively identified using electrocardiogram (ECG) signals. However, the complex temporal and frequency patterns in ECG recordings make accurate diagnosis challenging. Recent advances in deep learning have sign...
- Climate & EnvironmentOpen access
In regions where severe topographic constraints coincide with intensive human activity, the mechanisms underlying landscape ecological risk (LER) and its spatial differentiation remain poorly understood. In particular, the nonlinear responses and threshold effects arising from th...
- Biology
Abstract Human serum albumin (HSA) plays a key role in regulating the transport and bioavailability of therapeutic molecules, making protein–ligand interaction studies essential for assessing biomedical compatibility. In this work, the interaction of cotarnine and its derivatives...
- Materials & Energy
Abstract N-alkylamines serve as essential structural units in pharmaceuticals, agrochemicals, bioactive molecules, etc. Nevertheless, their conventional syntheses predominantly rely on metal-based catalysts, which frequently encounter challenges including metal leaching, easy poi...
- Biology
Abstract The development of long-acting MC4R peptide agonists remains challenging due to rapid clearance and structural sensitivity, where conventional permanent lipidation strategies often impair receptor engagement. Here, we report the discovery and characterization of TL10, a...
- Climate & EnvironmentOpen access
Balancing food production, ecosystem service value, and agricultural irrigation water consumption is a major challenge for sustainable agricultural development in China. However, quantitative evidence at the national scale remains limited on whether crop planting structure optimi...
- Engineering & Technology
Surface micro-structuring of TC6 alloy by diamond grit tool
In response to the escalating demand for functional surfaces in marine applications and aerospace, this study investigates the precision fabrication of microstructured surfaces on TC6 using structured diamond grit tools. A novel kinematic model is developed to reveal the formatio...
- Engineering & TechnologyOpen access
Abstract A symmetric bilinear form corresponding to the biharmonic operator is combined with a corresponding bilinear form for the Laplacian to create a temporally 4th order corrected leap-frog scheme for the wave equation. The boundary conditions are imposed weakly, which allows...
- Engineering & TechnologyOpen access
Abstract Prussian blue analogues have emerged as a promising cathode material owing to their open‑framework structure and high theoretical capacities; however, the presence and dynamic evolution of crystalline water severely constrain their electrochemical performance. Despite ex...
- Society & EconomicsOpen access
Abstract In recent years, the Luban Workshop has emerged in China as a key task of internationalizing China’s vocational education and to share teaching resources, teaching models, and professional criteria globally to cultivate talent and train high-end skilled technical personn...
- Health & MedicineOpen access
Digital ecosystems, misinformation exposure, mental-health vulnerability and unequal access to care create distinctive challenges for young people. Although youth participation in health governance is increasingly advocated internationally, structured evidence from youth delibera...
- Health & MedicineOpen access
Mastodynia is a common symptom in women with fibrocystic breast disease and can substantially impair quality of life. Although vitamin E is frequently used for symptom relief, the potential additional analgesic effect of fluoxetine remains unclear. This study aimed to compare the...
- BiologyOpen access
ABSTRACT The development of biocompatible and biodegradable drug delivery systems remains a major challenge in cancer therapy, particularly for the localized and sustained release of poorly soluble, unstable, and highly toxic compounds. 7‐Ethyl‐10‐hydroxycamptothecin (SN‐38), the...
- BiologyOpen access
Background The Lancet Oncology Commission on cancer genomics and precision oncology identified workforce capability, education, and training as major constraints to equitable implementation. As genomic and multi-omic technologies become integrated into cancer care, structured app...
- Engineering & Technology
Abstract. We study a simplified nonlinear thermoelasticity model on two- and three-dimensional tori. A novel functional involving the Fisher information associated with temperature is introduced, extending the previous one-dimensional approach from the first two authors [ SIAM J....
- BiologyOpen access
Agriculture 4.0 technologies such as automated machinery, precision farming, and data-driven decision-making can today help farmers manage the challenges of economic instability and climate adaptation. Yet uptake of on-farm technology is often variable, with reported barriers rel...
- Society & EconomicsOpen access
This study investigates the determinants of Organizational citizenship behavior for the environment (OCBE) in the retail sector, focusing on minimarkets in an emerging-economy context where empirical evidence remains scarce. It integrates employees’ green attitude and ambidextrou...
- Health & MedicineOpen access
Vascular calcification is a key indicator of cardiovascular risk, and dental imaging allows its visualization. Dental pulp calcifications (pulp stones) have been suggested as markers of systemic mineralization. This study aimed to assess the association between pulp stones and ex...
- Health & MedicineOpen access
Glaucoma is an ocular disease caused by the improper management of elevated intraocular pressure (IOP). IOP-lowering via topical administration is the first choice to prevent further progression. However, patients may forget to administer their medication, compromising IOP contro...
- Society & EconomicsOpen access
Heart failure (HF) is a progressive disease with complex pathogenesis involving inflammation, immune dysfunction, and metabolic abnormalities. Although C-reactive protein (CRP) is an established HF marker, the CRP-to-lymphocyte ratio (CLR) integrates inflammatory and immune respo...