Research works

Analysis of birefringence modulation performance in RM-embedded CO-polymer waveguides

Uncontrolled birefringence causes measurement errors and signal distortion in high-precision optical systems, yet existing modulation methods suffer from complex fabrication or poor stability. Polymer waveguides serve as low-cost, flexible alternatives to traditional lithium niob...

Improving Generative Deep Learning-Based SAR-to-Optical Image Translation through Spatiotemporal Feature Incorporation: A Case Study in Cropland

Synthetic aperture radar (SAR)-to-optical (S2O) image translation is an effective approach for reconstructing cloud-contaminated regions in optical imagery using corresponding SAR observations.However, its ability to reconstruct multispectral optical information is inherently lim...

Association between remnant cholesterol inflammatory index and new-onset stroke in different glycemic metabolic states: insights from the China health and retirement longitudinal study

The remnant cholesterol inflammatory index (RCII) has been proposed as a novel biomarker for lipid dysregulation and inflammation, and has also been suggested as a potential risk factor for diabetes. However, the association between RCII and the incidence of new-onset stroke acro...

A kirigami-inspired soft gripper based on liquid crystal elastomer integrated with strain sensing

Soft robotic grippers are capable of handling objects with diverse shapes and sizes. However, achieving reliable grasping of delicate objects and sustaining prolonged holding with minimal energy input remains challenging. This study reports a miniaturized liquid crystal elastomer...

A seven-gene signature diagnostic model for early-onset colorectal cancer and the tumor-suppressive role of SLC26A2 via redox modulation

The rising incidence and poor prognosis of early-onset colorectal cancer (EOCRC) highlight an urgent need for effective diagnostic biomarkers. This study integrates RNA sequencing data with machine learning algorithms to identify EOCRC-specific genes and construct a diagnostic mo...

Standardized lake fish community assessment using modified multi-mesh gillnets to minimize fish mortality

Systems for assessing the ecological status of lakes with respect to fish population are normally based on catches using conventional European Committee for Standardization (CEN) gill nets. A modified gillnet (MOD) design with less small-mesh and more large-mesh panel area , deve...

Nodular fasciitis of the nasal cavity with USP6 rearrangement: a case report

Nodular fasciitis (NF) is a benign myofibroblastic tumor characterized by rapid growth, self-limiting course, and rearrangement of the USP6 gene. While NF can occur in the head and neck region, cases originating within the nasal cavity are exceedingly rare. We herein report a cas...

Integrative multi-omics analysis identifies SMIM24 as a favorable prognostic biomarker in clear cell renal cell carcinoma

Clear cell renal cell carcinoma (ccRCC) exhibits substantial molecular and clinical heterogeneity, contributing to variable disease progression and therapeutic outcomes. We previously identified a de-clear cell differentiation (DCCD) tumor state characterized by loss of canonical...

Cascading effect of early sensory differences on subsequent autistic traits in infants later diagnosed with autism: a prospective cohort study

Sensory differences constitute core diagnostic features of autism. The cascading effect model posits that early sensory differences may be prospectively associated with subsequent autistic traits, whereas empirical evidence in infancy remains scarce. This study aims to characteri...

A clinically translatable coating-free strategy for 3D-printed porous titanium implants: TiO2 nanotubes simultaneously prevent infection and promote bone integration

Orthopedic implants face persistent clinical challenges of peri-implant infection and impaired osseointegration, especially in high-risk populations with trauma, osteoporosis, or diabetes. Herein, we report a coating-free strategy integrating three-dimensional (3D) printing and e...

Identification of vaccine candidates by immunization with a complex pool of recombinant VLPs

Identifying the regions of a protein that can be readily translated into an effective vaccine remains a major challenge in epitope-focused vaccine design, especially when a protein is poorly characterized. Here, we describe an immune-driven strategy for epitope identification whi...

Regime Equivalence and Refinement: Transport, Normal Forms, and the Boundary of Declared Change

Abstract This second-edition layer develops the retirement calculus implicit in Regime Equivalence and Refinement v1.0. Holding the frozen regime and carrier fixed, retirement removes declared demands and therefore moves in the direction opposite refinement: fewer demands induce...

A dual-mode radiofrequency ablation catheter with advanced thermal sensing for saphenous and perforator vein insufficiency: a preclinical study on goats

为克服现有进口器械热损伤风险高、 与国内临床常用的 6 Fr 鞘管不兼容等局限性, 我们研发了一款名为 Saphenus 的新型国产射频消融 (RFA) 导管系统。 其核心创新点包括: 6 Fr 外径设计 (适配国内常用鞘管), 独特的双模工作长度设计 (8 mm 用于穿通静脉, 80 mm 用于大隐静脉), 以及优化的温度传感机制以...

Effect of cobalt doping on NiSe2-based sensing electrode for non-enzymatic electrochemical ascorbic acid detection

Ascorbic acid is an essential antioxidant involved in redox homeostasis, immune response, and metabolic processes. The development of low-cost high accurate electrochemical sensors is critical to overcome conventional glass carbon electrodes (GCE). In this report, we report the f...

Patient-centered limb preservation in giant recurrent myxofibrosarcoma: a case-based review of goal-concordant care

Myxofibrosarcoma is an infiltrative soft-tissue sarcoma of the elderly with a high propensity for local recurrence; giant, recurrent, infected tumors with sciatic nerve encasement may prompt consideration of amputation when adequate resection is expected to leave a non-functional...

Continuous lactate-driven biohydrogen production from the organic fraction of municipal solid waste

The organic fraction of municipal solid waste (OFMSW) is a promising feedstock for biohydrogen production via dark fermentation. Lactate-driven dark fermentation (LD-DF) mitigates the impact of lactic acid bacteria (LAB) overgrowth, yet its application under continuous operation...

Peptide language pragmatic analysis and two-stage hierarchical learning framework for therapeutic peptide prediction

Therapeutic peptides exert pivotal effects in diverse biological processes, and have attracted significant interest in the field of biomedicine in recent years. However, most existing methods often fail to adequately capture the intricate interactions among amino acid residues an...

Development and quality evaluation of apple-enriched fermented whey beverage from dairy whey

Six fermented apple-whey beverage formulations were initially evaluated sensorially for formulation selection. The formulation containing 60% fermented whey and 40% apple concentrate was selected for further characterization and storage studies. The selected formulation was inocu...

Do elite soccer players meet nutritional requirements? A scoping review and meta-analysis

This scoping review and meta-analysis synthesised current evidence on energy and macronutrient intake and energy expenditure in elite male and female soccer players. Despite established nutritional guidelines, concerns persist regarding chronic low energy availability and its imp...

The Qualia Tomogram: A Generalized Projection-Slice Framework for Receiver-Conditioned Neural Reconstruction

The Qualia Tomogram develops a falsifiable projection-slice framework for studying how partial, receiver-conditioned neural measurements could support a shared, body-relative reconstruction. It connects the Self Aware Networks concepts of tonic context, Phase-Wave Differentials,...