Research works

Quantifying the fiscal benefits of obesity prevalence reduction in China

With obesity becoming increasingly prevalent in China, its impact extends beyond health losses to wider public finance pressures. This study assessed the fiscal implications of reducing obesity prevalence from the government perspective and explored the potential fiscal benefits...

Stakeholder perceptions of an early essential newborn care simulation-based training in western China: a qualitative study

Neonatal mortality remains a global concern, especially in China, where regional disparities persist. Early essential newborn care (EENC) consists of a set of evidence-based and cost-effective interventions, including but not limited to, skin-to-skin contact, neonatal resuscitati...

Discovery of a novel MurA inhibitor via AlphaFold 3 model-based virtual screening

S. aureus is one of the most important bacteria associated with human diseases. UDP-N-acetylglucosamine 1-carboxyethylene transferase (MurA) is an important enzyme involved in the synthesis of peptidoglycan in bacterial cell walls. The crystal structure of MurA from S. aureus has...

Voice metrics and workload in helicopter rescue: insights from ninety-six cockpit recordings

The relationship between subjective workload and task performance is multifaceted. In aviation research, task performance is typically evaluated using multiple variables. Voice metrics can provide valuable insights regarding operational improvements and offer objective assessment...

A Giant Ovarian Fibrothecoma Arising From Residual Ovarian Tissue Mimicking Advanced-Stage Ovarian Malignancy: A Short Report of Demons–Meigs Syndrome

The Annali Italiani di Chirurgia (ISSN/eISSN: 0003-469X/2239-253X) is the oldest surgical journal in Italy. It covers all aspects of surgery and its allied disciplines, including elective, emergency and experimental surgery, as well as problems involving technology, teaching, org...

Membrane behavior and diffusion in bentonite for different anions

Bentonite clay is widely used in engineered barriers, such as geosynthetic clay liners (GCLs), to safely contain wastes and chemicals. In addition to low hydraulic conductivity and diffusion coefficients, bentonite has been shown to exhibit membrane behavior (anion restriction) w...

Comparative effects of semaglutide tirzepatide and retatrutide on renal fibrosis in UUO and aged mice

Chronic kidney disease is a major health burden. Given the therapeutic potential of GLP-1 receptor agonists (semaglutide, tirzepatide, and retatrutide) in diabetic nephropathy, we evaluated their anti-fibrotic and anti-inflammatory effects in non-diabetic renal fibrosis using HK-...

Design of heat treatment and magnetic field-assisted machining for microstructure and surface corrosion control in Inconel 718

It has been demonstrated that Magnetic Field-Assisted Machining (MAM) has strong potential for improving surface quality and tailoring microstructure in hard-to-machine heat-treatable Inconel 718 (IN718). However, the influence of MAM on corrosion performance of IN718, particular...

Beyond HAS-BLED in very elderly patients with atrial fibrillation treated with direct oral anticoagulants: predictors of major bleeding in a real-world cohort

Bleeding risk assessment in very elderly patients with atrial fibrillation (AF) receiving direct oral anticoagulants (DOACs) remains challenging. The HAS-BLED score is widely used but may have limited applicability in this population. We aimed to evaluate its performance and to i...

Mitigating firm-capacity delay risk through stochastic planning of flexible generation and battery storage

Energy-transition plans often assume that committed firm-capacity projects are commissioned on schedule, yet delayed delivery can create temporary adequacy risks and require additional mitigation resources. This study develops a scenario-based stochastic adequacy-mitigation model...

Infectious complications following bispecific antibody or CAR T therapy in adult patients with hematologic malignancies: a retrospective database analysis

T-cell redirection therapies, including bispecific antibodies (BsAbs) and chimeric antigen receptor (CAR) T therapy, have transformed the treatment of relapsed or refractory hematologic malignancies. However, comparative data on infectious complications between these treatments r...

Volcano–climate interactions: reframing the volcano–climate puzzle

Explosive volcanic eruptions are major natural perturbations of the Earth system. By increasing stratospheric aerosol loading, they exert a dual radiative forcing: enhanced scattering of incoming solar radiation induces global surface cooling, while absorption of terrestrial radi...

Tailored novel nanocomposites for advanced elimination of methylene blue dye from water

Novel SrCO 3 /CuO/MgO/C (Abbreviated as CSM600) and SrCO 3 /CuO/MgO/Sr 2 CuO 2 CO 3 /Cu 2 SrO 3 /SrCuO 2 /C (Abbreviated as CSM800) multiphase nanocomposites were successfully synthesized through a Pechini sol–gel route followed by calcination at 600 and 800 °C. Structural analys...

Experimental methodology for evaluating enzyme kinetics and biocatalytic activity of antioxidant systems in pigmented Ficus leaves exposed to green-synthesized silver nanoparticles

Plant-derived biomaterials provide a sustainable platform for the development of functional nanostructures and biocatalytic systems. In this study, the kinetic properties and biocatalytic efficiency of catalase (CAT), peroxidase (POD), and polyphenol oxidase (PPO) were evaluated...

High-fidelity animal model simulation improves surgical competence in medical students

To determine whether a formal suturing simulation course using a realistic animal model improves medical students’ perception of their technical competence and their later self-confidence in a competency-based model of surgical education. The opportunities to acquire hands-on tra...

Binary Projections: How the Self-Inspection Mechanism of the Cosmic Living Organism Expands into Human Entire Cognitive System

Yuanxian Theory establishes four cosmic meta-laws—Cosmic Organism Law (COL), Dichotomous Cognition Law (DCL), Hexagonal Closure Law (HCL), Minimum Energy Manifestation Law (MEL)—as the foundation of all derivations, with Dichotomous Cognition Law (DCL) at the core: cosmic self-in...

BAM: A physics-informed self-supervised framework for near-real-time wildfire burned area mapping from multi-source earth observation

The operational monitoring of global wildfires is frequently constrained by the delayed availability of reliable reference labels, the latency of standard surface reflectance products, and spectral confusion between charred biomass and naturally dark surfaces. These limitations a...

Modular reconfigurable underwater robot (MRUR): a comprehensive review of structure, perception, and control

Modular reconfigurable underwater robots (MRURs) have attracted increasing attention due to their potential to overcome the limitations of conventional underwater robots with fixed structures and single-task capabilities. This review summarizes recent progress in MRUR from three...

Undecidability Does Not Kill Simulation: Provability, Execution, and the Missing Premise in Anti-Simulation Arguments

Arguments based on Gödel incompleteness and undecidable questions in physics are sometimes presented as proofs that the universe cannot be simulated. This paper reconstructs that argument in its strongest form and identifies a missing premise. Generating a process one step at a t...

PIGU expression is associated with poor prognosis and estimated immune cell infiltration in breast invasive carcinoma

Breast invasive carcinoma (BRCA) is a major cause of cancer-related mortality in women. PIGU , a subunit of the GPI-anchor biosynthesis complex, has been reported to be dysregulated in several cancers; however, its prognostic value and immune-related associations in BRCA remain u...