Research works

Pyrocarbon Hemiarthroplasty Via Lateral Approach for the Treatment of PIP Osteoarthritis

Hemiarthroplasty of the proximal interphalangeal (PIP) joint using a pyrocarbon implant was initially described for the salvage of nonreconstructable fractures with loss of 1 joint surface. Later, this method was used to treat osteoarthritis. PIP hemiarthroplasty is less invasive...

Effects of Adding BreatheMAX-Assisted Deep Breathing to Home-Based Spot Marching on Maximal Voluntary Ventilation and Peak Expiratory Flow in Young Adults with Overweight or Obesity: A Randomized Controlled Trial

Background: Overweight and obesity adversely affect respiratory mechanics and ventilatory capacity. This study evaluated the incremental effects of combined Spot Marching Exercise and BreatheMAX-assisted deep breathing (CSMEB) versus Spot Marching Exercise alone (SME) on pulmonar...

Toward AI-Driven Detection of Asymptomatic Chronic Conditions from Stool Metagenomics and Dietary Data: A Multimodal Deep Learning Framework for T1DM, T2DM, MOS/PCOS, Cancer, and Autoimmune Disease

Chronic non-communicable conditions—type 1 and type 2 diabetes mellitus (T1DM, T2DM), metabolic obesity syndrome (MOS), polycystic ovary syndrome (PCOS), colorectal and extra-intestinal cancers, and systemic autoimmune disease—share a prolonged asymptomatic phase during which con...

Clinical applications of selected liquid biopsy biomarkers in pancreatic cancer with a focus on ctDNA CTCs and exosome derived biomarkers

Pancreatic ductal adenocarcinoma (PDAC) remains a major clinical challenge because reliable biomarkers for early detection, risk stratification, and treatment monitoring are still limited. Liquid biopsy has emerged as a promising complementary approach that enables minimally inva...

Toward a framework of uncertainty in ill-structured problem solving

Abstract This study advances a framework for understanding uncertainty in ill-structured problem-solving contexts. A systematic review and qualitative synthesis of 74 peer-reviewed articles was conducted using thematic analysis and taxonomic coding to clarify how uncertainty is c...

Should I stay or should I go? Frog breeding responses to drought events and alien predators

Abstract Climate change is a major driver of biodiversity loss worldwide, increasingly acting through extreme climatic events such as droughts. Beyond their direct impacts on habitat availability, droughts can also generate indirect effects by altering ecological interactions, su...

Impermeability Theory in Algebraic Systems

We introduce impermeability as an external structural property of subsets of algebraic systems. An impermeable subset is defined by the requirement that an element of its complement remains outside the subset when operated on, from either side, with an element of the subset. Unli...

The Effect of Intercropping Leguminous Crops in the Winter Fallow Season of Mulberry Plantations on Soil Nitrogen and Phosphorus Status

To explore the effects of legume intercropping on soil nitrogen (N) and phosphorus (P) cycling processes in mulberry plantations during the winter fallow period, three treatments were set up: control (no intercropping, CK), single-legume intercropping (T1: Medicago polymorpha), a...

Climatic factors as drivers of elevational shifts in the montane forests-paramo boundary over the last 15,000 years in the northwest Andes

In this study, conducted in the Belmira paramo in the northwestern Andes of Colombia, we used pollen records to track vegetation changes over the past 15 calibrated thousand years before AD 1950 (cal kyr BP). Employing ordination (NMDS), species indicator, and wavelet analysis, w...

Characterisations of finite groups by subsets of commutators

Abstract Given a finite group 𝐺 and an element 𝑥 of 𝐺, let K x ⁢ ( G ) K_{x}(G) denote the set of commutators [ x , g ] [x,g] as 𝑔 varies through 𝐺. We prove that various group theoretical properties of 𝐺, for instance, nilpotency of several subgroups of 𝐺 and the existence of a...

Antiferromagnetic order and crystalline electric field in noncentrosymmetric hexagonal R E Ru 6 As 4 ( R E = Sm and Yb )

We investigated the electronic properties of $RE{\mathrm{Ru}}_{6}{\mathrm{As}}_{4}(RE=\mathrm{La}, \mathrm{Ce}, \mathrm{Sm}, \text{and} \mathrm{Yb})$ using single-crystalline samples grown by the Bi-flux method. These compounds crystallize in the noncentrosymmetric hexagonal ${\m...

High mobility p -type doping of hexagonal boron nitride films on diamond (100) substrates

The heteroepitaxy of hexagonal boron nitride (h-BN) on diamond exhibits significant potential for the advancement of diamond-based electronic devices. p-Type doping of h-BN is expected to provide sufficient carriers for forming a two-dimensional hole gas at the diamond interfaces...

Withania somnifera ameliorates endoplasmic reticulum stress in human hepatocellular carcinoma HepG2 cells

Abstract Objectives Endoplasmic reticular (ER) stress plays an important role in gene modulation and the consequent release of several inflammatory mediators i.e., cytokines and proteases, key players associated with systemic-induced inflammation in various liver diseases. Natura...

Research on the Evolution of Wellbore Pressure During Managed Pressure Casing Running

With the continuous advancement of deep and ultra-deep well drilling technologies, formations with complex pressure windows are becoming increasingly common. During casing running operations, it is necessary to ensure both leak prevention in loss-prone formations and pressure sta...

Ancient Babylonian Tablet Reveals World's Oldest Trigonometric Table — E8 Intelligence Research

FINDING: Babylonian Plimpton 322 is a sexagesimal trigonometric table based on exact Pythagorean triples, not a simple accounting record. | MATH: Base-60 (sexagesimal) system; Pythagorean triples generated via reciprocal pairs (p, q) yielding (p²−q², 2pq, p²+q²); tablet lists 15...

The ageing immune system and its battle with viruses

Graphical Abstract Virus-specific immunity and correlates of protection change across human life: children encounter first infections/vaccinations when they are immunologically naïve, whereas cumulative exposure histories in older adults shape their immunity.

A New Proof for The Banach–Zarecki Theorem

We present a modern and transparent proof of the Banach–Zarecki theorem, characterizing absolute continuity via continuity, bounded variation, and the preservation of Lebesgue null sets, while avoiding cumbersome estimates and classical summation arguments.

A Cross‐Kingdom Counter‐Mimicry Nanozyme Reverses Fungal‐Induced Neutrophil Paralysis and Establishes Protective Immune Memory

ABSTRACT Recurrent fungal infections caused by Candida albicans remain a formidable clinical challenge due to the pathogen's sophisticated orchestration of immune evasion. Herein, we report a “kill‐and‐reset” nano‐platform comprising a CuFe dual‐atom nanozyme core encapsulated wi...

Carrier, Interface, and Closure: A Claim-Controlled Reconstruction of the Unified Fields Research Program

This research status paper reconstructs the Carrier–Field–Residual–Gate–Closure program against standard literature in analytic number theory, Frobenius integrability, effective descent, dissipative field theory, and Hamiltonian computation. It presents the exact Archimedean inte...

HIOF • Cosmic Arithmetic — Paper II: Pouring Sand into Points

Holographic Information Ontological Framework — Cosmic Arithmetic (HIOF•CA)HIOF•CA is a nine-part theoretical series proposing that stable macroscopic order across physics, biology, and engineered computation can be read as the outcome of constraint-mediated coarse-graining rathe...