Research works

A spatio-temporal modelling of climate variability on respiratory disease morbidity in Kampala city, Uganda

Abstract Background : Climate change poses serious public health risks, particularly in rapidly growing urban areas. Similarly, the interaction between month and year was not statistically significant (edf = 0.75, p = 0.296), indicating a relatively stable seasonal pattern over t...

Multi-omics analysis of skin tissue metabolome and proteome reveals the repigment effect of Qubai tincture against vitiligo in mice

BackgroundVitiligo is an autoimmune-mediated dermatological disorder characterized by the progressive loss of functional melanocytes, leading to patchy skin depigmentation. The traditional Chinese medicine (TCM) strategy for treating vitiligo centers on nourishing the liver and k...

On finite trifactorised groups and Sylow and Hall theorems for skew braces

Abstract The aim of this short note is to show that the Sylow theorem (respectively Hall theorem) for finite skew braces proved by Truman in [4] is a direct consequence of the Sylow structure (resp. Hall structure) of a finite trifactorised group. A Cauchy theorem for finite skew...

Heuristic optimization of AI agents for Dhumbal

Abstract This study evaluates Artificial Intelligence (AI) agents for Dhumbal, a culturally significant multiplayer card game with imperfect information, by systematically comparing rule-based, search-based, and learning-based strategies. We formalize Dhumbal’s mechanics and impl...

Circadian temperature compensation is intrinsically linked with metabolism and redox signaling

Abstract Circadian rhythms are a universal property of organisms, and a defining property of these oscillators is the ability to maintain a precise period at different temperatures. Indeed, the discovery in the 1950s of this property, known as “temperature compensation,” was a wa...

S-AI-RLM: A Recursive Logic Machine

S-AI-RLM introduces a Recursive Logic Machine within the Sparse Artificial Intelligence paradigm to address a central limitation of contemporary probabilistic reasoning systems: strong empirical performance does not by itself provide guarantees of termination, logical correctness...

Market Volatility and Withdrawal Outcomes: Bootstrap Evidence from 100,000 Paths, with Left-Tail Emphasis

Addendum 1 to DAGM — bootstrap evidence from 100,000 paths per arm, with left-tail emphasis and the cost of a bequest promise.

Stakeholder collaboration and the future of sustainable tourism management in Cape Coast, Ghana from an economic and social sustainability perspective

Abstract Heritage tourism destinations in sub-Saharan Africa face a persistent tension between economic growth imperatives and social equity. This study examines how stakeholder collaboration shapes sustainable tourism outcomes in Cape Coast, Ghana, a UNESCO World Heritage destin...

Eigenvector varieties

Any linear space of square matrices has an associated eigenvector variety. Its points are eigenvectors of matrices from that linear space. We present a systematic study of eigenvector varieties, with focus on Lie algebras and Hamiltonians of quantum systems.

Explicit-Field-Resistance Gravity : Microscopic Properties, Coarse-Grained Bridge, and Unification of the Four Fundamental Forces

Abstract This paper proposes a new gravitational theory framework—Explicit-Field-Resistance Gravity (EFRG)—which explicitly embeds the field-resistance parameter into the gravitational equations. The core innovation lies in establishing a micro-macro unified framework: the micros...

Improvement of uncorrected visual acuity and contrast sensitivity using Aurovue Vivid Continuous Focus Vision (CFV) lens in cataract patients at RSCM Kirana

Abstract Background The primary goal of cataract surgery has evolved beyond visual restoration toward comprehensive refractive outcomes. In aging yet functionally active populations such as Indonesia, access to premium multifocal intraocular lenses (IOLs) remains limited, creatin...

No evidence of fine-scale local adaptation of winter moths to variable tree phenology

Spatial variation in plant phenology can impose strong selective pressures on herbivorous insects whose fitness relies on synchrony with host plants, promoting local adaptation to host timing. Winter moths (Operophtera brumata) have been shown to synchronize egg hatching with hos...

Isolation Through Orthonormal Rotation Holds

Per-tenant orthonormal rotation applied to attention K-vectors provides cryptographic isolation between tenants sharing a single language model instance. Within a tenant, rotation is an isometry — retrieval quality is preserved exactly. Across tenants, a wrong-key query returns c...

A Lindbladian for holographic Brownian motion

A bstract We derive a Lindbladian description of holographic Brownian motion in the high-temperature regime. Starting from the influence functional for a trailing string endpoint, we identify the corresponding quantum master equation and prove that it is completely positive and t...

Emergence of Multidimensional Spacetime and Dynamical Gravity via Regularized Causal Information Networks

The standard Λ‑CDM cosmological model faces severe empirical crises at high redshifts ($z>5$), highlighted by the James Webb Space Telescope’s (JWST) discovery of mature, massive galaxies that strain classical hierarchical‑structure‑formation timelines. To eliminate epistemologic...

LUXVAR: A Constructed Language with Distinctive Morphemic Structure and AI-Recoverable Morpheme Families

LUXVAR is a constructed symbolic language developed within the VARZIN research framework. This study presents a computational analysis of LUXVAR morphology, phonotactics, semantic structure tests, and AI-based clustering benchmarks. Main findings include: • Non-random morphologic...

EphA4 Mediates Pro- and Antitumoral Effects Through Upstream Negative Regulation of AKT in Head and Neck Squamous Cell Carcinoma

Head and Neck Head and Neck Squamous Cell Carcinoma (HNSCC) is driven by an immunosuppressive tumor microenvironment (TME). We examined the immune-modulatory role of EphA4 in HNSCC using spatial analysis, multi-compartment RNA-sequencing from Oral Cavity Squamous Cell Carcinoma (...

Conserved structural features of RNA export pores spanning the double membrane of arterivirus and coronavirus replication organelles

ABSTRACT Coronaviruses and arteriviruses are distantly related positive-stranded RNA virus families within the order Nidovirales . Both transform intracellular membranes into double-membrane vesicles (DMVs) that serve as replication organelles. Newly made viral RNA presumably exi...

Instantaneous radiative forcings due to the first indirect effect linked to low-level liquid clouds in the Amazon

Abstract. Much of the present uncertainty in effective radiative forcing due to aerosol–cloud interactions (ERFaci) arises from aerosol–cloud adjustments. Nevertheless, estimating instantaneous radiative forcing due to aerosol–cloud interactions (IRFaci) remains important because...

What Survivors Remembered: Cognitive and Experiential Themes in Trauma Narratives From the Deadliest Mass Shooting in Modern American History

This study examined cognitive and experiential patterns in the trauma narratives of 42 survivors (74% women; M age = 42.1) of the Route 91 Harvest Festival shooting, the deadliest mass shooting in modern American history. We conducted a codebook thematic analysis of written narra...