Research works

A Recurrent Tympanicum Paraganglioma With a SDHD Pathogenic Variant: First Reported Case

ABSTRACT Objective The aim of this study is to describe a clinical case of a SDHD germline mutation associated tympanic paraganglioma (TPGL). Patients A female patient seen in the otology clinic at a tertiary care center with a diagnosis of tympanic paraganglioma and significant...

Coreless exoplanets induced by metal–silicate miscibility

The rocky interiors of exoplanets are generally expected to differentiate into a silicate mantle and a metallic core due to the immiscibility of metal and silicate under typical planetary formation conditions. Here, we use large-scale molecular dynamics simulations driven by mach...

Silica Nanoparticle-Reinforced Wormlike Micellar Gels for High-Temperature Flow Redistribution in Heterogeneous Porous Media

Maintaining the rheological performance of wormlike micellar fluids at elevated temperatures remains challenging. Conventional viscoelastic surfactant (VES) systems may undergo thermally induced micellar scission and loss of gel-like viscoelasticity at elevated temperatures. In t...

Suburbanisation effects on light pollution in Warsaw’s natural areas assessed using drone imagery and machine learning

Suburbanisation is a major driver of artificial light at night (ALAN) in urban environments, yet its specific impacts on ecologically valuable areas remain insufficiently quantified. This study investigates the effects of suburbanisation on light pollution (LP) across eight ecolo...

Collaborative Archaeology: How Native American Knowledge Enhances Our Collective Understanding of the Past

When I first opened this book, the title had led me to believe I’d encounter an edited volume with a series of case studies sweeping across Native North America. Instead, I quickly discovered that ...

Full Darkon-Euler-Lagrange Equations of Motion and Field Dynamics of the Darkon-Allotey Macro-Wave Formalism in Big Boot Gauge Theory

We present a complete variational field theory derivation of the Euler-Lagrange Equationsof Motion (EoM) governing the Darkon-Allotey Macro-Wave Quantum Mechanics framework within Big Boot Gauge Theory (BBGT). By explicitly varying the non-associative Lagrangian density L_ZIP def...

A Geometric Origin of Flavor II: Quark and Mixing Theorems, a Supergravity Vacuum, and a Falsifiable Neutrino Spectrum from the Degree-Three Monopole Bundle

A companion paper derived the charged-lepton sector — Koide’s relation and the mass hierarchy 1 : 206.770 : 3477.5 — from a single geometric object: a degree-three monopole bundle over an internal two-sphere, probed at unit charge by one spinorial doublet. This paper retains the...

Research and Field Test of Autonomous Underwater Vehicles Cooperative‐Navigation Method in Terrain Mapping

ABSTRACT A cooperative‐navigation algorithm based on an extended Kalman filter (EKF) is proposed for Leader–Follower autonomous underwater vehicles (AUVs) to address inconsistencies in inter‐vehicle navigation coordinate systems caused by the absence of geo‐referencing signals in...

Ion-Regulated ReversibleSwitching of Photocurrentsin Molecular Junctions

Abstract The switching of photoinduced charge transport in large-area carbon-based molecular junctions incorporating tetraphenyl porphyrin (TPP) molecules has been observed by reversibly introducing hydrogen ions into the molecular layer. The TPP layer acts as an ionophoric layer...

Closure Fibers and Defect Representation Task Quotients, Compression, Witnesses, and the Structure of Intrafiber Information

Closure Mathematics — Series Architecture This paper is the second in a sequence developing Generalized Closure Mathematics as a systematic study of mathematical structure retained within and between closure classes. Paper I, Foundations of Generalized Closure Mathematics: Closur...

An integrated nanopore–microfluidic platform for low-voltage electroporation of delivering self-amplifying RNA into dendritic cells

Efficient delivery of large, negatively charged self-amplifying RNA (saRNA) into dendritic cells (DCs) is critical for next-generation cancer vaccines. However, this remains challenging due to the high sensitivity of DCs to chemical carriers and high-voltage electroporation. In t...

Urinary metabolomic signatures associated with left ventricular hypertrophy in chronic kidney disease: an exploratory gas chromatography-mass spectrometry study

Abstract Although left ventricular hypertrophy (LVH) is common in people with chronic kidney disease (CKD); its mechanisms are not well understood. Metabolomic profiling may reveal novel mechanistic pathways linked to cardiac remodelling in CKD patients. In this single-centre cro...

A Comprehensive Assessment Framework for the Sustainable Ecological Carrying Capacity of Chinese Cities Based on Time-Series Uncertainty and Interval-Valued Fermatean Fuzzy Sets

The assessment of sustainable ecological carrying capacity (SECC) serves as a crucial scientific foundation for supporting high-quality urbanization, advancing ecological civilization, and achieving the strategic goals of the “Dual Carbon” initiative. However, existing assessment...

Falls in Older Adults: The Role of the Nurse Practitioner

Falls among older adults represent a public health crisis with increasing death rates. Nurse practitioners face a dual challenge: managing acute postfall injuries and preventing future occurrences. While immediate assessment for hidden injuries using advanced imaging is critical,...

Soil Carbon Fractions and Aggregation Regulate N 2 O Emissions and Microbial N‐Cycling Genes: A Case Study Across Tropical Paddy Soils With Contrasting Organic Matter Levels

ABSTRACT Background : Nitrous oxide (N 2 O) is a major greenhouse gas, and its production is shaped by soil organic matter (SOM). Yet, how different SOM‐derived labile carbon fractions regulate N 2 O remains unclear, especially in tropical paddy soils where weak SOM stabilization...

Tetrahedral DNA nanostructure–gated solution-phase CRISPR/Cas12a system for probe immobilization-free, reagent-efficient, and dual-phase electrochemical detection of circulating microRNAs in liquid biopsy

Liquid-biopsy nucleic acid biomarkers hold strong promise for non-invasive cancer diagnostics, yet their ultralow abundance presents substantial analytical challenges. Conventional electrochemical biosensors rely on complex probe immobilization, whereas emerging homogeneous strat...

The Political Economy of Modern Monetary Theory: A Marxist Critique

Modern Monetary Theory (MMT) has emerged as a significant heterodox challenge to neoclassical orthodoxy, arguing that sovereign currency-issuing governments face no intrinsic financial constraints and can use fiscal policy to achieve full employment. MMT offers important critique...

Assessment of the risk of obstructive sleep apnea syndrome in patients with chronic obstructive pulmonary disease in Ouagadougou, Burkina Faso

Objectives: Chronic obstructive pulmonary disease (COPD) and obstructive sleep apnea syndrome (OSAS) are public health issues. The association of COPD and OSAS, called overlap syndrome, increases morbidity and mortality. This study aimed to assess the proportion of medium-to-high...

Ferroptosis in Anthracycline Cardiotoxicity: Mechanisms, the Cardioprotection Paradox and the Limits of Single‐Pathway Thinking

ABSTRACT Anthracyclines remain among the most effective cytotoxic drugs, but their cumulative cardiotoxicity limits dosing and threatens survivors with heart failure. The discovery that doxorubicin kills cardiomyocytes substantially through ferroptosis—an iron‐dependent, lipid‐pe...

Efficient Removal of Tartrazine from Aqueous Solutions Using Eco-Friendly Aqueous Two-Phase Systems (ATPSs)

Synthetic dyes are widely used in industry; however, their release into the environment without adequate treatment poses serious risks because of their toxicity and adverse effects on human health and aquatic ecosystems. Although conventional methods are effective, they are often...