Research works

Early implant stability in reconstructed alveolar bone supported by iliac crest grafts using bone-enhancing drills: a retrospective clinical study

Autogenous iliac crest grafts are widely used for reconstruction of extensive alveolar defects because of their osteogenic potential and ability to support implant placement. However, limited evidence exists regarding early implant stability patterns in reconstructed alveolar bon...

Identification of RAB36 and NINL as potential diagnostic biomarkers for gestational diabetes mellitus and polycystic ovary syndrome

Gestational diabetes mellitus (GDM) and polycystic ovary syndrome (PCOS) are common endocrine and metabolic disorders in women, with PCOS increasing the risk of GDM. However, shared molecular markers that could support early diagnosis and the mechanisms underlying them remain ins...

Use and perceived utility of ChatGPT among participating medical students in selected MENA settings: a cross-sectional survey

ChatGPT is a language model, developed by OpenAI, that uses contextual understanding that allows it to generate relevant responses based on current input and previous context. ChatGPT has infiltrated many fields, including medicine. As the demand for medical education tools is in...

Age-Adjusted Phenome-Wide Analysis Identifies Liver Enzymes and Lipid Markers Associated with Prevalent Breast Cancer in the Qatar Biobank

Most evidence linking phenotypic traits to breast cancer risk derives from Western populations, leaving a critical gap for the Middle East and North Africa region, where breast cancer presents at younger ages and where demographic, metabolic, and lifestyle profiles differ substan...

Morphological Hijacking in Frozen Language Models: Recovering Structured Representations and Testing the Limits of Algebraic Composition

This revised manuscript presents a controlled study of morphological hijacking in frozen language-model representations using the synthetic LUXVAR/VARZIN framework. The study shows that adversarial surface structure can dominate frozen representations, while a lightweight trained...

Simultaneous broad-spectrum antibacterial and regenerative therapy for diabetic wounds using sonosensitive peptide composite hydrogel

Diabetic wound infections remain highly refractory to treatment due to persistent bacterial colonization, oxidative stress, dysregulated inflammation, vascular insufficiency, and impaired extracellular-matrix remodeling. Current therapeutic strategies remain limited by poor tissu...

Slow stellar halo rotation as a signature of disc flips and GES-like mergers

Abstract The stellar halo of the Milky Way (MW) exhibits a weak net prograde rotational signal (vφ ≲ 25 km s−1), yet its origin remains unexplained. To investigate this, we use the Auriga cosmological simulation suite of MW-mass haloes to probe the rotation of stellar haloes over...

Detecting cognitive motor dissociation in unresponsive brain-injured patients: a prospective cohort study using active task-based EEG

This study aimed to assess the prevalence and prognostic value of cognitive motor dissociation (CMD) detected by active task-based electroencephalography (EEG) in a cohort of patients with disorders of consciousness (DoC). In a prospective cohort study, we enrolled 56 consecutive...

CPR duration and achievement of ROSC After ICU cardiac arrest: a single-center study in Al-Jouf, Saudi Arabia

Cardiac arrest in the intensive care unit (ICU) remains associated with substantial mortality despite advances in resuscitation care. Resuscitation duration is an important marker of resuscitation outcome following in-hospital cardiac arrest. This study evaluated the association...

Availability and equity analysis of China’s National Reimbursement Drug List-negotiated drugs: a national cross-sectional analysis

Ensuring equitable access to innovative drugs is crucial for public health. Despite the inclusion of innovative drugs on China’s National Reimbursement Drug List, disparities in availability persist across regions and healthcare facility levels. This study aims to assess the avai...

Three latent subtypes of suicide risk and network characteristics of scale item associations among adolescents with major depressive disorder: a cross-sectional study

This study aimed to identify latent suicide risk subtypes among first-episode, treatment-naive adolescents with major depressive disorder (MDD), and to explore the item-level association patterns across subtypes, so as to provide evidence for optimizing stratified suicide risk sc...

Sex and Self-reported Race: Factors Associated with Anal Mucosal Melanoma and Anal Mucosal Pigmentation?

Anal canal melanoma (ACM) is a rare, aggressive malignancy with an ominous prognosis. However, its associated factors are largely unknown. Therefore, we investigated potential independent associations of sex and self-reported race with ACM and physiological anal canal pigmentatio...

Collagen remodeling is elevated in fibrotic hypersensitivity pneumonitis and may distinguish it from idiopathic pulmonary fibrosis

Idiopathic pulmonary fibrosis (IPF) and fibrotic hypersensitivity pneumonitis (fHP) are two common causes of pulmonary fibrosis. Unlike IPF, fHP is caused by a persistent immune response to an antigen. Misclassification of fHP and IPF can lead to significant delays in antifibroti...

Type IV pilus length determines virulence by regulating a putative subpopulation of non-contributing filaments in Pseudomonas aeruginosa

Many clinically important bacterial pathogens, including Pseudomonas, Vibrio, Neisseria, and Acinetobacter species, employ dynamic extracellular appendages called type IV pili (T4P) to facilitate virulence through cyclical extension and retraction of pilus filaments. To dissect h...

Healthcare Intelligence Platform: Medication Intelligence Data Mart Architecture

This technical documentation establishes the conceptual and logical architecture framework for the Medication Intelligence Data Mart within the Healthcare Intelligence Platform (aligned under the broader master reference infrastructure of DOI: 10.5281/zenodo.22255118). Functionin...

Kramer’s rule with or without transcutaneous bilirubin screening for neonatal jaundice in primary healthcare clinics: a cost-minimization analysis

Neonatal jaundice (NNJ) is a prevalent condition requiring timely detection and management to prevent severe hyperbilirubinemia and its long-term sequelae. In Malaysia, NNJ screening in primary care predominantly relies on Kramer’s Rule (KR), followed by total serum bilirubin (TS...

Age-dependent sex differences in acute kidney injury among patients with chronic kidney disease

Patients with chronic kidney disease (CKD) are susceptible to acute kidney injury (AKI), which worsens clinical prognosis. Sex differences in AKI incidence and subsequent kidney prognosis remain uncertain in CKD. This multicenter, retrospective cohort study analyzed outpatients w...

The Missing Column: measured institutional silence on men and boys in international accounting systems

USD 71.8 billion a year is marked for gender equality by stated intent. The men-and-boys column beside it is not zero: it is structurally uncountable. At UN Women, 320 girls-only publications stand against 4 boys-only; in 24,043 words of UN child-justice guidance the word boys do...

Buying Time: T cells and Delayed HIV Rebound After Treatment Interruption

Charles R Crain, Gaurav D Gaiha, Rajesh T Gandhi; Buying Time: T cells and Delayed HIV Rebound After Treatment Interruption, The Journal of Infectious Dise

Multimodality imaging and surgical management of a rare combination: type 2A bridging bronchus, pulmonary artery sling, and atrial septal defect, a case report

We report the case of a 15-year-old female presenting with exertional syncope and a history of refractory respiratory symptoms. Comprehensive preoperative multimodality imaging—including echocardiography, multi-detector computed tomography (MDCT) with three-dimensional reconstruc...