Research works

Nonselective beta-blockers and hepatic encephalopathy in liver cirrhosis:A meta-analysis of randomized controlled trials

BACKGROUND: Liver cirrhosis leads to portal hypertension and related complications, including ascites, esophageal varices, and hepatic encephalopathy (HE). Non-selective beta blockers (NSBBs) decrease portal pressure, but it is not yet clear whether they contribute to HE developm...

The Dimensional Collapse Mechanism in the HDC

https://www.hdc-theory.comEarlier papers of the Hierarchical Dimension Cascade (HDC) characterised the dimensional collapse by V″(ε_c) < 0. With the bare potential V(ε) = λε² this condition cannot be met, and the matter density does not appear in it. This paper shows that the con...

UC Food Waste: A Multimodal Robotic Perception Dataset for Robust Contaminant Detection in Complex Biowaste Scenes

Automated organic waste recovery represents a significant challenge for computer vision, characterized by extreme spatial clutter and the material degradation inherent in industrial waste streams. While multimodal imaging provides a potential pathway for material identification,...

Culinary Chemistry as a Platform for Interfacial Materials Design

ABSTRACT This Review examines culinary systems as experimentally accessible models of interfacial materials design. Culinary operations, including emulsification, foaming, gelation, spherification, controlled heating, smoking, and dehydration, govern gas‐liquid, oil‐water, solid‐...

Unifying Nanosecond Electrical and Optical Excitations in Perovskite Light‐Emitting Diodes

ABSTRACT Metal halide perovskites offer a promising pathway toward solution‐processable monolithic lasers. In the pursuit of direct electrical pumping, optical excitation is widely employed as the primary route for investigating the gain potential at the device level. However, th...

Subjective Neurophysiological Perception and Behavioral Avoidance in Women with Fibromyalgia: An Analysis of Pain and Affective Symptoms

This study examined associations among pain intensity, psychological distress, neurophysiological perception, and avoidance behaviors in women with FMS. Participants included 120 women with FMS and 110 age-matched healthy controls who completed the Visual Analog Scale (VAS), Depr...

E8 Phi‑Resonant Number‑Theory Waveguide — E8 Intelligence Research

The 240 root vectors of E8 spontaneously form phi‑coupled triadic clusters that lock into a coherent 132 Hz oscillation, creating a self‑sustaining lattice waveguide. By imprinting algebraic ideals onto the phase offsets of these triads, the waveguide supports resonant modes whos...

Hemispheric Asymmetry of Neuroimaging Biomarkers in Early Onset Alzheimer's Disease: Clinical and Cognitive Outcomes

Objective Individuals diagnosed with Alzheimer's disease (AD) often exhibit amyloid, tau, and atrophy predominantly in the left or right hemisphere, but group‐level analyses typically ignore inter‐individual variability and changing asymmetry patterns when averaging data across p...

Quantum Resonance Unified Model (QRUM): Foundational Hypothesis, Scientific Research Programme, Authorship and Priority Documentation

This document provides a consolidated statement of the foundational hypothesis, authorship, scientific provenance, and research development of the Quantum Resonance Unified Model (QRUM), also referred to as the Einstein–Quantum Resonance Spacetime Extension (EQRSE). It identifies...

Homework Responsibility and Parent–Adolescent Communication: Maternal and Paternal Associations with Academic and Psychological Adjustment Among Chinese Adolescents

Responsibility for homework and parent–adolescent communication may have different associations with adolescent adjustment. Using two waves of the China Education Panel Survey (2013–2015), we examined these parent-specific behaviors in outcome-specific analytic samples ranging fr...

Pathways Linking Perceived Environmental Attributes of Community Public Spaces and Older Adults’ Mental Well-Being: A Parallel Mediation Analysis of Physical Activity and Social Participation

Against the backdrop of population aging, community public spaces are important neighborhood settings for older adults’ daily activities, social ties, and mental well-being. However, few studies have integrated multidimensional perceived environmental attributes, parallel physica...

Patient-Reported Changes in Alcohol Use Following Glucagon-Like Peptide-1 Receptor Agonist Initiation

This survey study with a nationally representative sample evaluates whether individuals who initiate glucagon-like peptide-1 receptor agonists (GLP-1 RAs) report reducing alcohol consumption after starting the drug.

Preclinical and first-in-human evaluation of VG-3927/SAR448851, an oral small-molecule TREM2 agonist for Alzheimer’s disease

Microglial dysfunction is increasingly implicated in Alzheimer’s disease (AD) pathogenesis, with loss-of-function variants in the microglial receptor TREM2 as major risk factors for late-onset AD. We report VG-3927, an oral, CNS-penetrant small-molecule TREM2 agonist that engages...

Subnational variation in sustainable nitrogen management across Indian croplands and its linkage with state-level governance

Abstract Sustainable food production requires the reconciliation of agricultural productivity with environmental protection, a challenge especially acute in rapidly intensifying systems. India exemplifies this tension through heavy reliance on synthetic fertilizers and strong reg...

Design, Synthesis and Biological Evaluation of Thiazole Derivatives: An Integrated Molecular Docking and Density Functional Theory Investigation

A series of nine thiazole-hydrazone hybrids (D1-D9) was prepared in two steps: 5-chloro-1,3-dimethyl-1H-pyrazole-4-carbaldehyde was condensed with thiosemicarbazide, and the resulting thiosemicarbazone was cyclized with substituted phenacyl bromides. The products were characteriz...

Feasibility of a school-based cardiopulmonary resuscitation educational programme incorporating microlearning and gamification in primary school children: a prospective observational study

Abstract Cardiorespiratory arrest (CRA) is a priority public health problem whose survival depends largely on the early action of the community as the first link in the life-saving systems (chain of survival). In this context, international organisations such as the European Resu...

Reassessment of the morphological evidence for hominin hybrids in the Levant

The Levantine hominin fossil and archaeological records have played a central role in long‐standing palaeoanthropological debates over origin models and possible interbreeding between Neanderthals ( Homo neanderthalensis ) and Homo sapiens . Recent research has provided a strong...

Is liposomal iron superior in treating anemic children with congenital acyanotic heart diseases? A randomized controlled clinical trial

Abstract Background Children with congenital heart disease (CHD) often suffer from Iron deficiency anemia (IDA), which is linked to poorer clinical outcomes. Liposomal iron has been proposed as a promising advancement in iron supplementation across diverse populations. This study...

AI-Driven Human Task Substitution: Evidence from Google Translate and ChatGPT

We examine how different generations of artificial intelligence (AI) substitute for human knowledge worker tasks, leveraging two sequential natural experiments in the translation industry. We study the introduction of Google Neural Machine Translation (GNMT), a predictive, task-s...

Magnetic signatures in merger products

All template inlist files used to create the stellar models used in the 'Magnetic signatures in merger products' paper, as well as our additions to the 'run_star_extras.f90' file used to enable a nu_max-based stopping criterion. The single-star models were calculated based on the...