Research works

Pulsed two-photon scattering from a single atom in a waveguide with delay-modified temporal correlations

Quantum nonlinearity is an essential ingredient for many quantum technologies, but often the nonlinearity is too weak to be exploited at the few-photon level. However, few photons interacting strongly with single quantum emitters in a waveguide environment can impact a significan...

ERFMTDA: Predicting tsRNA–disease associations using an enhanced rotative factorization machine

Abstract Motivation tRNA-derived small RNAs (tsRNAs) have emerged as a novel class of regulatory molecules implicated in the pathogenesis of many human diseases, making them as promising biomarkers and therapeutic targets. However, existing computational methods for tsRNA–disease...

Identification of living (Rose Bengal)-stained benthic foraminifera using automated image recognition

Abstract. Living and fossil benthic foraminifera are widely used as bioindicators of ecosystem quality, but their analysis is time-consuming. With the help of artificial intelligence, models for the automatic identification of fossil planktonic foraminifera and, more recently, be...

Acceptability of advanced Controlled Human Infection Models: The case of a pneumococcal challenge in people living with HIV and mycobacterial challenge with Bacillus Calmette Guerin in Malawi

Abstract Background Controlled Human Infection Models (CHIM) in which volunteers are experimentally exposed to pathogens are used to study pathogenesis and down select among treatment and vaccine candidates. Scientifically, CHIM studies are best conducted among at-risk population...

Impact of the modified Frailty Index-5 on treatment selection and prognosis in octogenarians with bladder cancer eligible for radical cystectomy: a single-center, retrospective study

<title>Abstract</title> Background Developing treatment strategies for bladder cancer in octogenarians remains challenging owing to concerns regarding surgical invasiveness and the risk of undertreatment. We aimed to evaluate the effect of the modified Frailty Index-5 score on tr...

Sensory Abnormalities and Pain in the Donor Sites of Radial Forearm and Fibula Free Flaps—A Systematic Review

Background and Objectives: Free flap reconstruction is the gold standard for complex head and neck defects following oncological ablation. While surgical techniques have improved flap success rates, donor site sensory morbidity remains relatively understudied. The radial forearm...

From Taxonomy to Causality: Exploring Construction Dispute Factors Using a Gaussian KGE, CN, and DEMATEL-Based Approach

Abstract Despite advances in construction project management and technology, disputes remain a persistent challenge that significantly undermines project quality, cost, and schedule performance. A major reason is that dispute causes are often multifaceted and interdependent, yet...

Energy extraction from a rotating Buchdahl star via magnetic reconnection

Abstract In this work, we investigate the magnetic reconnection (MR) process as a mechanism for energy extraction from a rapidly rotating Buchdahl star (BS), one of the most compact horizonless objects that can, in principle, possess a spin parameter exceeding the extremal limit...

Latent gene network expression underlies partial re-evolution of a polyphenic trait in the worker caste of ants

Polyphenisms–where alternative phenotypes develop from a single genome in response to environmental cues–are not only widespread in nature, but also occur at multiple levels of biological organization, from cells to individuals to societies. Polyphenism is thought to promote phen...

Dual-Channel Energy Transfer from Ligand-Centered Singlet and Triplet States to Trivalent Lanthanide Ions

Abstract Efficient light harvesting and subsequent energy transfer (EnT) to trivalent lanthanide ions (LnIII) are critical for achieving high-performance luminescent LnIII complexes. However, because of the complexity of the underlying dynamic processes, in-depth investigations o...

Forecast of building materials and their related environmental impacts: comparing wood-based and conventional construction pathways

<title>Abstract</title> The building sector is a major contributor to global greenhouse gas emissions (GHGe), necessitating carbon mitigating strategies to reduce its environmental impact. This study investigates the environmental implications of two construction pathways in Denm...

Unveiling GmCS1 Promote Branch Development by Regulating Plant Hormones in Soybean

Soybean (Glycine max (L.) Merr.) was originally domesticated in China and is a kind of significant leguminous crop, which can fix atmospheric nitrogen to bioavailable nitrogen. Ceramides, intermediates of sphingolipids, are crucial structural components in membrane formation and...

Finite-time braiding dynamics within topological nanowire qubits

Topological quantum computing has largely evolved toward a paradigm of manipulating edge-localized Majorana within p-wave topological superconducting nanowires. To bridge the gap between physical qubit systems and quantum algorithms, we perform a dynamical analysis to extend what...

A biobank-scale method for learning modulators of gene-environment interaction underlying human complex traits from multiple environmental exposures

Abstract It is increasingly recognized that genetic effects on complex traits and diseases are shaped by environmental context. Biobanks that measure diverse environmental exposures alongside genotypes and phenotypes at scale enable systematic study of gene-environment (G×E) inte...

An angular-momentum-preserving dissipative model for the point-mass N-body problem

Abstract A simple mathematical model emulating energy dissipation due to tidal effects is proposed. In this model, forces acting between masses remove energy but preserve the total angular momentum of the system. We study the effect of such forces on the particular family of orbi...

Conceptual Shift inOur Understanding of DegenerateRadical Spin Systems: Spin-Rotation Coupling Turned on Its Head

Abstract For most chemists, Kramers’ degeneracy refers to the fact that for any radical system, every potential energy surface is at least doubly degenerate (with spin up and spin down, time-reversed solutions) for all nuclear positions X. Yet, as is well-known to the community o...

Transdisciplinarity 3.x: A White Paper on Metatheory, Reflexivity, Developmental Capacity, Adaptive Leadership, Hybrid Cognition, and Innovation in a Complexity-Saturated Age

This paper introduces Transdisciplinarity 3.x (TD 3.x) as an emerging next phase of transdisciplinary thought and practice for a complexity-saturated age. TD 3.x argues that complex problems require more than stakeholder inclusion, disciplinary boundary crossing, or procedural di...

Chronic toxicity thresholds for fish early life stages exposed to 226Ra in water

In 2021, a consensus was established to generate toxicity data for 226Ra in water with the objective to develop a Canadian water quality guideline that would effectively allow policy makers to set discharge limits for 226Ra that are protective for aquatic ecosystems. In the prese...

Predictability of exergy destruction in helically coiled tube heat exchangers: global, pitch-specific and hierarchical correlations

Purpose This study aims to quantify second-law performance in a vertically oriented helically coiled tube heat exchanger (HCTHEX) and develop predictive correlations for the dimensionless exergy-destruction fraction ϕD=E˙D/E˙in,total across operating conditions and coil pitches,...

Empowering medical educators to teach planetary health: development and outcomes of a curriculum integration training

<title>Abstract</title> <bold>Background</bold> Planetary Health (PH) content is increasingly recognized as essential for medical education. For longitudinal integration across the curriculum, medical educators can serve as change agents and multipliers. A targeted training that...