Research works

Vector-valued optimal transport: from dynamic to static formulations

Abstract Motivated by applications in classification of vector valued measures and multispecies PDE, we develop a theory that unifies existing notions of vector valued optimal transport, from dynamic formulations (à la Benamou-Brenier) to static formulations (à la Kantorovich). I...

Between-session chasing via time of return in online eCasino gambling

Abstract Background and aims Chasing refers to continuing and/or intensifying gambling following losses (loss-chasing) and/or wins (win-chasing). It is commonly captured between sessions, i.e., returning another day/time after losses or wins in prior sessions. Between-session cha...

A Hyperbolic Model for Two-Layer Thin Film Flow with a Perfectly Soluble Anti-Surfactant

Abstract. We consider the motion of a two-layer thin film that consists of two immiscible viscous fluids and is endowed with an anti-surfactant solute. The presence of such solute particles induces variations of the surface tension and interfacial stress driving a Marangoni-type...

The ladder of abstraction in statistical graphics

Graphical forms such as scatterplots, line plots, and histograms are so familiar that it can be easy to forget how abstract they are. As a result, we often produce graphs that are difficult to follow. We propose a strategy for graphical communication by climbing a ladder of abstr...

Soil health-based business models: perspectives and policy implications

Abstract. Soil health is foundational to ecological sustainability, economic productivity, and societal wellbeing. However, fragmented perspectives on what constitutes “healthy soil” hinder coherent policies and business models. This article addresses that gap by offering a value...

Antimicrobial resistance in Ecuador: A One Health situational analysis of governance, infrastructure, and equity gaps

Abstract Antimicrobial resistance (AMR) represents a growing global public health threat, undermining therapeutic efficacy and disproportionately affecting vulnerable populations. In Ecuador, the situation is exacerbated by weak surveillance systems and fragmentation among the hu...

Paying upfront: successful initial infections protect against severe future infections

Abstract Understanding the consistency with which individual hosts respond to repeated pathogen exposures is crucial for accurately modeling pathogen transmission and eco-evolutionary dynamics. When hosts face repeated pathogen exposures, immune memory is expected to reduce the p...

Bayesian inference of lineage trees by joint analysis of single-cell multimodal lineage-tracing data with BiLinT

Abstract The advent of single-cell lineage-tracing technologies has enabled simultaneous measurement of gene expression and lineage barcodes. However, integrating these modalities for high-resolution lineage reconstruction has remained challenging due to limitations of methods th...

Mendelian randomization and drug repurposing analysis identifies APOE as a potential therapeutic target for low back pain

Abstract Background: Low back pain (LBP) is a prevalent chronic pain syndrome primarily driven by spinal degeneration, causing persistent disability and reduced quality of life. Despite available interventions, identifying novel therapeutic targets remains imperative for modifyin...

What Jobs Do Workers Want? Worker Preferences in Global Value Chains

ABSTRACT What do workers in global value chains (GVCs) consider a good job? Research on work in GVCs largely studies compliance with standards set from the top‐down rather than worker preferences. Understanding worker preferences is crucial because workers are the intended benefi...

Younger Dryas Glacial Advances on the Tibetan Plateau

The Younger Dryas (YD) terminated the last glaciation and initiated the Holocene, which was accompanied by widespread glacial advances. Traditional scaling models, production rates, and outlier screening approaches for 10Be exposure dating often yield inconsistent formation ages...

Impact of a prolonged nationwide residents’ strike on acute ischemic stroke care in a metropolitan city

Abstract BackgroundAcute ischemic stroke (AIS) requires timely management in both prehospital and in-hospital phases to optimize outcomes. In 2024, South Korea experienced a prolonged nationwide residents’ strike that disrupted the healthcare system, potentially affecting AIS man...

Low-dose interval radiotherapy combined with tirelizumab and SOX chemotherapy neoadjuvant therapy for locally advanced gastric/gastroesophageal junction adenocarcinoma: study protocol of a prospective, single-center, single-arm clinical trial

Abstract Background：Gastroesophageal junction (G/GEJ) cancer is a global health burden with poor prognosis, especially for locally advanced or metastatic cases. While perioperative chemotherapy improves outcomes, survival remains limited. Immunotherapy combined with chemotherapy...

Experiences of mental health support services in a community sample of parents of children with special educational needs and disabilities

Parents of children with Special Educational Needs and Disabilities face challenges on top of everyday parenting, placing them at higher risk of mental health difficulties. However, this could be alleviated by appropriate and timely targeted mental health services. This study exa...

Primary central nervous system histiocytic sarcoma with skull base and ventricular dissemination: a case report and literature review

Abstract Purpose The primary objective of this case report is to highlight the clinical challenges and diagnostic difficulties of histiocytic sarcoma (HS) involving the central nervous system (CNS). This case emphasizes the importance of accurate diagnosis in patients presenting...

Observations of groundwater-surface water exchange effects on emerging pollutants in a subtropical catchment

The occurrence of emerging pollutants (EPs) in aquatic environments is a major threat to natural ecosystems and human health, but the connections between EPs in surface water and groundwater have been largely unexplored. Here, a total of 38 EPs, including antibiotics, per- and po...

Nomogram model based on dual-energy CT quantitative parameters and radiomics for preoperative prediction of microvascular invasion in hepatocellular carcinoma

Abstract Objective To explore the potential value of a nomogram model based on dual-energy CT (DECT) quantitative parameters and radiomics for preoperative prediction of microvascular invasion (MVI) in hepatocellular carcinoma. Methods A retrospective analysis was conducted on 14...

Urolithin A mitigates behavioural and synaptic deficits associated with epilepsy

Abstract The persistence of drug-resistant epilepsy highlights the need for new therapeutic interventions that target novel mechanisms with homeostatic regulations while minimizing side effects. Slow-acting drugs, particularly small molecules of natural origin with anti-epileptog...

VIProDesign: viral protein panel design for highly variable viruses to evaluate immune responses and identify broadly neutralizing antibodies

Motivation: Highly mutable viruses continuously evolve, with some posing major pandemic risks. However, standardized neutralization assays and up-to-date viral panels are often lacking, limiting evaluation of immunogens and identification of broadly neutralizing antibodies. Closi...

Freshness flavour perception via quantum-inspired and quantum ligand-based virtual screening

Abstract Flavour perception is a complex and critical biological process in the food industry in general and in beer production in particular. Taste is influenced by the simultaneous interaction of a large number of molecules present in food and beverages with specific receptors...