Research works

Multi-objective computational design optimization of a Total Disc Replacement implant

Abstract While cervical arthroplasty using Total Disc Replacement (TDR) implants is an established treatment for persistent neck and arm pain, revision rates limit it from reaching its full potential. To address the underlying complications, we developed finite element simulation...

Using the WHO Hospital Emergency Unit Assessment Tool to assess changes in Emergency Care Capacity in a United Kingdom Major Trauma Centre

Abstract Background We reviewed a Major Trauma Centre (MTC) in the UK over an Emergency Department (ED) transition using the World Health Organization (WHO) Hospital Emergency Unit Assessment Tool (HEAT). HEAT has previously been used in low- and middle-income countries. This is...

Impacts of anthropogenic aerosols on a snowfall event – a case study in the Guanzhong Basin and its surrounding areas, China

Abstract. Impacts of anthropogenic aerosols on clouds and snowfall during winter precipitation events remain highly uncertain, particularly under heavy pollution. A winter snowfall event over the Guanzhong Basin (GZB) and its surrounding regions (GZBs), China, has been simulated...

Scaling of poroelastic coarsening and elastic arrest in crosslinked gels

Recent experiments on crosslinked gels quenched from solvent-rich to solvent-poor conditions show solvent-rich domains embedded in a gel-rich matrix. These domains coarsen and then undergo kinetic arrest at micron scales for hours, before macroscopic drainage to equilibrium over...

From words to sentences: designing and evaluating a parent-facing sign language learning app

Abstract To prevent language deprivation, hearing parents of deaf and hard-of-hearing children need to learn sign language as soon as possible after their child’s hearing loss is identified. However, sign language resources for parents are limited and often lack focus on sentence...

Measurement report: Development of a portable peroxy radical measurement system and application for diagnosing local ozone formation and transport

Abstract. Atmospheric total peroxy radicals RO2* (RO2∗=HO2+∑RO2) play central roles in tropospheric chemistry, governing the formation of ozone and secondary aerosols. However, due to their extremely low concentrations and high reactivity, direct observation of RO2* remains chall...

Emergence of novel SARS-CoV-2 variants keeps slowing down

Abstract Background Although COVID-19 pandemic has no longer been classified as an international public health emergency of concern after May 2023, multiple variants with different characteristics keep emerging. Given the complex spatial-temporal characteristics of epidemics, res...

Why grounded large language models fail without domain-specialized retrieval: an experimental scientometric study in solar physics

Abstract Recent applications of large language models (LLMs) in scientometric analysis often assume that the underlying evidence space is neutral and pre-given. We challenge this assumption empirically by demonstrating that retrieval infrastructure constitutes a methodologically...

Impact of extreme rainfall on triggering conditions and susceptibility for shallow landslides: a case study in the Alpes-Maritimes region (France)

Abstract. Prediction of shallow landslides at the regional scale generally relies on statistical analyses of landslide inventories. Rainfall-duration thresholds and susceptibility maps are among the most common approaches to anticipate future landslide occurrences. However, the o...

Non-uniformly elliptic variational problems on BV

Abstract We establish $$\operatorname {W}^{1,1}$$ W 1 , 1 -regularity and higher gradient integrability for relaxed minimizers of convex integral functionals on $$\operatorname {BV}$$ BV . Unlike classical examples such as the minimal surface integrand, we only require linear gro...

Moisture-induced degradation of clay-bearing sandstone

Abstract Clay-bearing sandstones used in the construction of historic monuments, churches, and castles are highly susceptible to contour scaling, which manifests as fractures parallel to the exposed facades. Repeated wetting–drying cycles accelerate material degradation through s...

Observation of erratic non-Hermitian skin localization and transport

Abstract Localization is a pervasive phenomenon across physics, shaping transport from electrons in solids to light and sound in engineered media. In traditional settings, disorder strongly impedes transport, resulting in dynamical localization or, at best, sub-ballistic or diffu...

Microsolvation of Protonated Glycine: Infrared Spectra from Data-Driven Quantum Many-Body Simulations

Abstract Understanding how hydration reshapes the structure and conformational flexibility of biomolecular ions is essential for connecting gas-phase spectroscopy to behavior in aqueous environments. Glycine, the simplest amino acid, exhibits rich microsolvation behavior, with co...

Optimizing passive strategies for eco-residential energy efficiency in China's hot summer/cold winter zone: A Yancheng case study

This research evaluated the energy efficiency of an advanced eco-residential design in Yancheng, China, utilizing dynamic simulations with EnergyPlus and OpenStudio. The study focused on transitional climates marked by hot summers and cold winters, comparing three residential mod...

Dosimetry and immunohistochemistry study to establish radiolabelled prostate-specific membrane antigen (PSMA) as a potential theranostic target in high-grade glioma treatment

Abstract Prostate-specific membrane antigen (PSMA) is upregulated in high-grade glioma (HGG). This study aimed, firstly, to establish dosimetry for the radionuclide [68Ga]-PSMA-11 in HGG patients; secondly, to determine theoretical tumour doses for [177Lu]-PSMA, a potential thera...

Spatial heterogeneity in post-fire permafrost evolution as revealed by satellite radar observations

Abstract. Wildfires, which have profound impacts on permafrost environments, are expected to increase in frequency and intensity as a result of climate change. This study aims to enhance our understanding of how wildfires affect permafrost by investigating multiple Arctic tundra...

A cross‑sectional survey and content analysis of local youth vaping prevention initiatives

Abstract Background Youth vaping is an increasing public health concern in the UK. While national strategies address regulation, little is known about local authority-led vaping prevention initiatives. This study synthesised information on existing local approaches to identify th...

Evaluating cellular communication sensing for lapse risk prediction during early recovery from alcohol use disorder: A longitudinal observational study

Alcohol Use Disorder (AUD) is a chronic, relapsing condition, and identifying periods of elevated lapse risk remains a major challenge in supporting recovery. An automated recovery monitoring and support system using personal sensing and machine learning may help detect when indi...

Walk Based Laplacians for Modeling Diffusion on Complex Networks

Abstract We develop a novel framework for modeling diffusion on complex networks by constructing Laplacian-like operators based on walks around a graph. Our approach introduces a parametric family of walk-based Laplacians that naturally incorporate memory effects by excluding or...

On The Geometry of Time in Rational Agency

Standard economic theory treats time as an exogenous, linear parameter that indexes choice and coordination. This paper argues that such treatment obscures a constitutive feature of rational agency. We develop a coherence-based framework in which the temporal structure relevant t...