Research works

Loss of Osmoregulation of OmpC Porin Occurs if Escherichia coli are Deficient in cAMP Receptor Protein

In Escherichia coli, the regulator OmpR and EnvZ respond to cyclic AMP and are directly responsible for the regulation of outer membrane porin proteins OmpC and OmpF. We observe that increasing levels of OmpC expression in wildtype strains exposed to increasing osmotic pressure....

Accessing Diverse C(sp3)-Rich Cyclophane Linkers in Macrocyclic Peptides via Nickel-Mediated Deaminative Macrocyclic Arylation

Abstract Within macrocyclic peptides of both natural products and pharmaceutical targets, aryl rings play a crucial role in linker structure, and C(sp3)-rich cyclophane linkers can imbue beneficial physicochemical properties. Yet, methods to deliver C(sp3)-rich cyclophane linkers...

Emerging evidence suggests that circadian disruption and muscle wasting form a self-reinforcing loop

Circadian disruption and skeletal muscle wasting frequently co-occur in critical illness, shift work, and aging. We propose a bidirectional self-reinforcing loop in which each process amplifies the other. Environmental disruption of the skeletal muscle clock impairs protein turno...

Erçek Gölü’nün Yüzey Alanı Değişimleri ve Hidroklimatik Duyarlılığı

ÖzÇalışma, Doğu Anadolu Bölgesi’nde kapalı havza niteliği taşıyan Erçek Gölü’nün 1986–2025 dönemindeki yüzey alanı değişimlerini ortaya koymayı ve bu değişimleri iklimsel değişkenlerle ilişkilendirerek gölün hidroklimatik duyarlılığını değerlendirmeyi amaçlamaktadır. Çalışmada, y...

Correlating growth time with stoichiometry and electronic structure in WS2 nanoflakes grown by quasi-van der Waals molecular beam epitaxy on quartz

Controlling the electronic properties of two-dimensional tungsten disulfide (WS 2 ) requires precise understanding of how growth conditions govern atomic ordering and stoichiometry. However, direct correlations between growth parameters and the resulting electronic structure of W...

ZAPP: a zero-aware photovoltaic power prediction framework

Predicting photovoltaic power generator outputs is not easy, especially when the values are near zero, because even very small errors can lead to large percentage errors. We introduce a new forecasting framework, ZAPP (Zero-Aware Photovoltaic Power Predictor), that handles near-z...

Probabilistic Time-Variant Flexural Capacity Model and Flexural Bearing Fragility for Reinforced Concrete Beams under Steel Reinforcement Corrosion Induced by Concrete Carbonation

Abstract Steel reinforcement corrosion induced by concrete carbonation is the main reason for the degradation of the load-bearing capacity of reinforced concrete (RC) structures exposed to the atmospheric environment in urban areas. A probabilistic framework is proposed in this p...

Non-Euclidean Toroidal Topography in Large Language Models: Compact Riemannian Manifold Embeddings, Geodesic Attention, and 3D Photonic Co-Simulation Verification

Conventional Transformer neural networks embed token representations within flat Euclidean latent spaces RD . Despite their empirical utility, Euclidean geometries ex- hibit severe isotropic distance concentration in high dimen- sions, lack periodic boundary-free inductive bias,...

Mixed-mechanism glaucoma associated with primary iris pigment epithelium cysts: a case report

Abstract Background We present a rare case of bilateral primary iris pigment epithelium (IPE) cysts associated with mixed-mechanism glaucoma and explore the potential role of mechanically mediated pigment dispersion in its pathogenesis. Case presentation A 60-year-old male presen...

Geometry-tuned PDMS embedded FBG sensors for low- and ultra-low frequency vibration monitoring

This work reports the design and experimental characterization of two femtosecond-laser-inscribed fiber Bragg grating (FBG) vibration sensors based on direct polydimethylsiloxane (PDMS) encapsulation, for low- and ultra-low-frequency monitoring. FBG accelerometers for this regime...

Clinical and imaging characteristics of myelinated retinal nerve fibers: associations with refractive error and visual acuity

Abstract Purpose To characterize the clinical and imaging characteristics of myelinated nerve fibers (MNF) and evaluate their association with refractive error and visual acuity. Methods Retrospective observational case series of 367 eyes of 323 patients diagnosed with MNF betwee...

Association between distance from the angle recess to the tube entry site and corneal endothelial cell loss after PreserFlo MicroShunt implantation

Abstract Purpose To investigate the association between anterior segment optical coherence tomography (AS-OCT)–derived tube parameters and corneal endothelial cell density (ECD) changes after PreserFlo MicroShunt (PMS) surgery in primary open-angle glaucoma (POAG) and exfoliation...

Facial emotion recognition and disgust proneness in misophonia: findings from a clinical case-control study

INTRODUCTION: Misophonia is characterized by decreased tolerance to specific sounds, often occurring in interpersonal contexts and accompanied by intense emotional, physiological, and behavioral responses. Disgust and anger are among the most prominent emotional reactions in miso...

Where are the Missing Masses in the Missing Masses? The Sociology of a Few Cosmic Problems

Some 35 years ago, in ‘Where are the Missing Masses? The Sociology of a Few Mundane Artifacts’, Bruno Latour asked where the missing masses of sociology were. Inspired by an analogous problem in cosmological physics, he argued that sociologists should attend to nonhumans in their...

Light modulates organ-specific gibberellin–abscisic acid crosstalk during drought response in Arabidopsis thaliana

Abstract Main conclusion Continuous blue light enhances drought tolerance in Arabidopsis by modulating ABA and GA pathways, whilst controlled GA catabolism, especially via GA2ox7/8, is important for stomatal regulation and drought adaptation. Abstract In response to drought, plan...

Heptagonal Cubic Field Generates E8 Root Partition via 132Hz Spectral Cascade — E8 Intelligence Research

The cubic field generated by 2cos(2π/7) through Chebyshev T7 periodic points provides a decomposition of E8's 240 root vectors into 7 symmetry-equivalent classes of 30 roots each, with the 132Hz phason spectrum acting as a spectral marker that distinguishes each class. This parti...

Can AI Assistants Trigger Mental Illness in Users?

As conversational artificial intelligence models become ubiquitous fixtures in professional and personal workflows, the nature of human-tool interaction has the potential to gradually shift from mechanical utility to parasocial dependency. While existing literature frequently add...

Ammonia-induced corrosion of Fe- and Ni-based alloys at 400 °C-1000 °C: Degradation mechanisms and materials suitability for ammonia-handling components

Ammonia is a promising carbon-free fuel for future energy systems. However, ammonia-induced corrosion remains a critical challenge for structural alloys. This study evaluates the corrosion susceptibility and degradation mechanisms of Fe-based alloys (SUS304, SUS316, and SUS310) a...

Geometry vs Binary: Quantum Physics Puzzles — quantum geometry entanglement entropy unsolved pro — E8 Intelligence Research

## Binary Failure → Geometry Solution **Analysis of Findings:** The search results reveal a critical fault line in quantum physics: **entanglement entropy** — the measure of quantum correlations — is fundamentally a *geometric* object (area laws, holographic surfaces, tensor netw...

Theory of the TDH — Perpetually Creation and Evolution of the Universe: The Universal Hybrid Regime Framework - Volume II: Multi-Agent Populations and Assimilation Networks (Version 2.0)

Title Theory of the TDH — Perpetually Creation and Evolution of the Universe: The Universal Hybrid Regime Framework - Volume II: Multi-Agent Populations and Assimilation Networks (Version 2.0) Version 2.0 Date of Submission 2026-10-17 Authors Thai, Hau Dinh (Pen-names: TDH, or Th...