Research works

A Dragonfly Wing-InspiredMXene-Reinforced Soy ProteinAdhesive with Balanced Strength, Toughness, and Multifunctionality

Abstract Replacing petroleum-derived wood adhesives with soy protein isolate (SPI) offers a sustainable alternative, yet the practical application of SPI is severely hindered by its intrinsic poor water resistance and mechanical fragility. To overcome these drawbacks, we develope...

Aggregation-Induced Emission: Illuminating the Path from Photothermal Ablation to Systemic Immunity

Abstract Cancer photothermal immunotherapy has attracted great attention in cancer treatment for its ability to trigger systemic antitumor immune responses and reverse tumor immune tolerance, offering prospects for clinical application. However, conventional photothermal agents s...

Oral nonpeptide GLP-1 receptor agonist VCT220 for obesity treatment: a randomized, double-blind, phase II trial

VCT220 is a novel nonpeptide, orally available glucagon-like peptide-1 receptor agonist (GLP-1RA) designed to reduce the complex administration of injectable GLP-1RAs and the limited bioavailability of on-marketing oral agents for obesity care. We conducted a multicenter, randomi...

Navigating innovation and risk: evaluating European consumer perceptions of gene editing and pesticide use in watermelon production

Abstract Background Perceived risks associated with food production are a major concern among European consumers and strongly influence debates on sustainable agricultural practices. In particular, the adoption of precision-bred (gene-edited) crops and the use of alternative pest...

Your Insured's AI Agent Caused the Loss: Was It Authorized to Act?

This paper examines a developing insurance problem created by autonomous and semi-autonomous AI agents: when an insured deploys an AI agent that causes a financial, operational, contractual, cyber, or physical loss, who bears responsibility and how should insurers evaluate the re...

Otolith-based growth reconstruction and comparative evaluation of back-calculation methods in Reba carp, Cirrhinus reba (Hamilton, 1822)

Context Understanding growth patterns is essential for effective fisheries management and conservation of freshwater fishes, for economically important species with limited otolith-based growth studies. Cirrhinus reba, a valuable minor carp in the Ganga River, lacks comprehensive...

Precision monitoring of leaf area index and chlorophyll content of major field crops in Northern Europe using UAV remote sensing and radiative transfer modeling

Abstract Purpose Long-term monitoring of crop biophysical and biochemical traits remains challenging in high-latitude regions due to short growing seasons, frequent cloud cover, and highly variable weather. In this context, unmanned aerial vehicles (UAVs) offer flexible, high-res...

An Icosahedral Six-Well Construction for the Max-Mid Strain Constraint: A Candidate Counterexample via Convex Integration

Miller and Sawyer introduced the max-mid class of square-integrable trace-free symmetric matrix fields and conjectured that its intersection with the strain constraint space L^2_st is trivial. This preprint considers six trace-free symmetric matrices associated with the six unori...

TGS THEORY: A CANDIDATE UNIFIED FRAMEWORK FOR GODEL INCOMPLETENESS, TURING UNDECIDABILITY, AND SHANNON INFORMATION

This work proposes a candidate unification of three fundamental limitation principles:G¨odel incompleteness, Turing undecidability, and Shannon information constraints. The centralobject of the theory is the resolutive deficit, defined textually as the difference between the info...

CACA guidelines for the management of adult cancer pain

Abstract Cancer pain, one of the most prevalent and distressing symptoms in cancer patients, is closely associated with cancer diagnosis, therapeutic interventions, quality of life, and survival outcomes. Effective cancer pain management requires multidisciplinary collaborative a...

A portable nanobiosensor with machine learning: enabling multi-cytokines point-of-care testing and early identification of sepsis immunoparalysis

Abstract Sepsis immunoparalysis (SIs) is a major factor contributing to organ dysfunction. However, emergency departments (EDs) and intensive care units (ICUs) currently lack a rapid workflow for early identification of SIs. Herein, an innovative strategy for early SIs identifica...

On the pathway of changing emotions—a qualitative study of emotional changes in breast cancer patients from the first detection of the tumor to breast surgery

Abstract Background The trajectory of breast cancer is a dynamic experience, both physically and emotionally, and despite the same diagnosis, the emotional reactions to events during the healing process are quite individual. Therefore, to support the coping processes with the dis...

Automated OCEL transformation for real-time conformance in complex manufacturing

Abstract Object-Centric Process Mining (OCPM) provides a sophisticated framework for analyzing multi-object interactions in complex manufacturing; however, its practical adoption is limited by the labor-intensive transformation of heterogeneous data into Object-Centric Event Logs...

E=mc²=Work: A Classical-Mechanics-Based Ontological Reinterpretation of Mass-Energy Equivalence

This paper demonstrates that the mass-energy equivalence equation E=mc² is not an exclusive discovery of relativity theory, but rather a necessary consequence of the classical mechanics definition of work (W = F × d) under the boundary conditions of light. Using only F=ma and W=F...

Effects of direct cannabinoid receptor modulation on alcohol craving and withdrawal: a systematic review

Abstract Background Alcohol use disorder (AUD) is a prevalent condition associated with significant morbidity and mortality rates. Existing pharmacological and psychosocial treatments offer limited long-term effectiveness. At present, there is a critical need for novel AUD treatm...

Observation of lunge-feeding by pygmy blue whales (Balaenoptera musculus brevicauda) in the Wetar Strait of Timor-Leste

An aerial observation of of pygmy blue whales (Balaenoptera musculus brevicauda) sub-surface feeding in the Wetar Straight of Timor-Leste. Based on current understanding of their foraging ecology, these whales were probably feeding opportunistically on krill-like zooplankton.

Investigating Knowledge of Applied Behavior Analysis Strategies Among Teachers and Teacher Assistants of Students With Autism Spectrum Disorder in Private Special Education Schools in Kuwait

Applied behavior analysis (ABA) is a critical evidence-based framework for developing effective interventions for students with autism spectrum disorder (ASD). In Kuwait, where the majority of students with ASD are enrolled in private special education schools, the ABA competency...

Spectral Properties and Localization Barriers of Co-occurrence Gram Matrices in Set Families

In this paper, we establish the spectral framework governing $G = V^T V$ for arbitrary $0\text{-}1$ matrices. Combining Rayleigh-Ritz variational bounds with Gershgorin disk localization, we prove a general spectral inequality relating element frequencies to local average set siz...

Fibrinogen as aMolecular Bridge Linking SARS-CoV-2Immune Evasion and Endothelial Access?

Abstract SARS-CoV-2 exploits multiple cellular entry routes. Beyond ACE2-mediated entry, we propose that the spike protein binds fibrinogen not only to facilitate immune evasion but also to position the receptor-binding domain for integrin-mediated uptake. This molecular bridge m...

Assessment of combustion behavior and catalytic converter deposits in a CI engine operated with MWCNT-enriched pongamia biodiesel: experimental study

Abstract Although biodiesel seems to be a promising alternative fuel for compression ignition (CI) engines, its use can cause deposit formation on the catalytic converter and impact engine durability. The effects of 30 ppm multi-walled carbon nanotube (MWCNT) dispersed Pongamia b...