Research works

Conservation and divergence within the Arabidopsis TPL/TPR corepressor family

Abstract The TOPLESS (TPL) and TOPLESS-RELATED (TPR1–TPR4) corepressors, collectively the Arabidopsis TPX family, are recruited by client proteins to regulate nearly every major plant regulatory program. Here, we dissect the conservation and divergence between paralogs using a co...

CLASPP: A unified model for predicting post-translational modifications

Abstract Post-Translational Modifications (PTMs) are a fundamental mechanism for regulating cellular pathways and increasing the functional diversity of the proteome. Accurately predicting the PTM types that are likely to occur at a given site in the primary sequence is a key cha...

Polymer Quantum Mechanics on Compact Configuration Spaces

“Polymer quantum mechanics” is the name given to a quantization scheme inspired by loop quantum gravity in which the configuration space of the theory is chosen to have a discrete topology. Polymer quantization yields a representation of the canonical commutation relations that i...

European Network for Optimization of Veterinary Antimicrobial Therapy (ENOVAT) guidelines for antimicrobial and non-steroidal anti-inflammatory drug use in bovine respiratory disease

<ns5:p> Background Bovine respiratory disease (BRD) is a major cause of morbidity, mortality, impaired welfare, production loss, and antimicrobial use in cattle. These European Network for Optimization of Veterinary Antimicrobial Therapy (ENOVAT) guidelines provide evidence-based...

Applying the UNECE PIERS Evaluation Methodology for the SDGs to Support the Implementation of Green PPP Projects and Infrastructure: Lessons from Slovenia

Robust evaluation methods are essential for assessing the sustainability of public–private partnerships (PPPs) and advancing the Sustainable Development Goals (SDGs). This study examines the United Nations Economic Commission for Europe (UNECE) People-first PPP and Infrastructure...

Design and fabrication of a multifunctional Zn-Fe@Ag nanocomposite for effective treatment of infections wounds

<title>Abstract</title> Infectious wounds, a common bacterial infection in clinical practice, often experience significantly delayed healing due to local bacterial colonization, macrophage polarization imbalance, and tissue regeneration inhibition, posing persistent challenges fo...

The Hidden Geometry of Transformer Weights: A Canonical Basis for Interpreting Transformer Language Models

Version 2 of the paper "The Hidden Geometry of Transformer Weights". Rotating a Transformer language model into a coordinate system alignedwith its own weight matrices — the canonical basis — reveals a hiddeninternal structure. Version 1 established the descriptive phenomena.Vers...

AI-driven Wi-Fi radar people counting for intelligent IoT and distributed sensing systems

<title>Abstract</title> Counting humans in indoor environments is a key capability for intelligent Internet of Things (IoT) systems, enabling applications such as smart home energy optimization, occupancy-aware automation, and real-time decision-making. With the proliferation of...

Analysis of Perinatal Care in Zambia in the Context of WHO Recommendations

Background/Objectives: Perinatal care is essential for the health and well-being of women and adolescent girls from conception through the first year postpartum. The World Health Organization (WHO) provides evidence-based recommendations aimed at improving the quality of antenata...

Characterization and Anti-Allergic Activity of Exopolysaccharides from a New Probiotic Lacticaseibacillus casei LZ9183

Lactic acid bacteria exopolysaccharides (LAB EPS) have garnered significant interest owing to their beneficial biological properties and safety. This study aimed to screen LAB EPS with comprehensive biological activities and anti-allergic potential from four high-yield strains, i...

Impairment of placental function and maternal-fetal immunity cross-talk by per- and polyfluoroalkyl substances during early pregnancy

Per- and polyfluoroalkyl substances (PFAS) are persistent environmental pollutants that have been associated with adverse pregnancy outcomes and immune dysfunction. However, the impact of PFAS on trophoblast-mediated immune interactions at the maternal-fetal interface remains unc...

Contagion of Affinity: Predicting CDS Spikes in Global Systemically Important Banks

This paper examines the predictive power of credit default swap (CDS) spread correlations in the context of the 2023 Credit Suisse failure. Using a two-window design, we separate a 50-week pre-crisis period from the final two-week “jump” window and evaluate whether historical mar...

Scanning X-ray microdiffraction studies of protein accumulation and tissue loss in thin sections of human brain tissue in Alzheimer’s disease

Neurodegeneration in Alzheimer's disease is characterized by accumulation of pathological protein deposits including Aβ plaques, tau tangles and diffuse neuropil threads accompanied by wide-spread tissue loss. While dense protein deposits are readily observed by conventional meth...

Sustainable Metal–Organic Framework Water Harvesters in the Artificial Intelligence Era

Abstract Metal–organic frameworks (MOFs) are promising candidates for water harvesting due to their tunable pore environments, which can be precisely engineered to capture and release water in arid conditions. Integrating artificial intelligence (AI) into MOF discovery can accele...

Photonic-crystal hydraulic manometry quantifies epithelial basal compression for rapid, label-free functional screening

Polarized epithelia integrate barrier sealing, vectorial ion-water transport, and cytoskeletal mechanics, yet scalable assays that report this coupled functional state in real time remain limited. Here, we introduce photonic-crystal hydraulic manometry (PCHM), which quantifies ou...

Electromagnetic Signatures from Primordial Black Holes in the Solar System

Primordial black holes (PBHs) in the asteroid-mass range, with typical masses 1017g≲M≲1023g, have drawn significant recent attention as viable dark matter candidates. The peak frequencies of photons emitted via Hawking radiation from asteroid-mass PBHs range from infrared to γ-ra...

GRB 260310A / SN 2026fgk: A Multi-Wavelength Study of a Nearby Underluminous Long GRB and SN with a Complex Afterglow

Abstract We present a comprehensive multi-wavelength study of GRB 260310A / SN 2026fgk, a nearby (z = 0.153), long-duration gamma-ray burst (GRB) with an exceptionally underluminous prompt γ-ray emission and a Comptonized spectrum. The burst occurred at the edge of a blue host ga...

We don't care how much you sweat: An epistemic framework for behavioral and brain science laboratory infrastructure

For decades, behavioral and brain research has advanced by isolating single variables or brain regions to study behavior and performance. However, it has become increasingly clear that reductionist methods struggle to capture the complex, dynamic, and context-dependent nature of...

Gut microbiota dysbiosis remodels the multi-tissue transcriptional landscape of the host

<title>Abstract</title> Background The gut microbiota exerts a profound influence on host physiology, but its systemic impact on gene expression across diverse tissues remains poorly characterized. Results This study investigated the transcriptional effects of gut microbiota depl...

EmotionaL and Language Recovery in Aphasia (ELLA): Codesigning and Proof-of-Concept Testing a Novel Intervention

Purpose: People with aphasia are at risk of becoming depressed, anxious, and isolated. They want therapy to focus on improving communication, confidence, and finding ways to live well; family members want to be involved in the therapy process. We aimed to codesign and test a nove...