Research works

Advances in Aerobic Exercise for Pulmonary Arterial Hypertension: Mechanisms of Action and Clinical Insights

Pulmonary arterial hypertension (PAH) is a progressive disease characterized by elevated pulmonary artery pressure and pulmonary vascular resistance, leading to right heart failure and death in severe cases. PAH is classified as Group 1 pulmonary hypertension (PH). Although Group...

The mediating role of social determinants of health in the association between adverse childhood experiences and later-life cardiovascular disease

To investigate the longitudinal association between adverse childhood experiences (ACEs) and incident cardiovascular disease (CVD) in later life, and to examine whether the integrated construct of adult social determinants of health (SDH) mediates this association among middle-ag...

From Limb Salvage to Prosthetic Rehabilitation After Severe Traumatic Hand Injury Complicated by Complex Regional Pain Syndrome: A Case Report

Background/Objectives: Severe traumatic injuries of the upper extremity present a major therapeutic challenge because of extensive tissue damage, severe pain, loss of function, and substantial psychosocial consequences. Continuous multidisciplinary rehabilitation that adapts to t...

Adaptive Civic Infrastructure in Refugee-Led Organizations: A Theoretical Framework for Youth Participation

Abstract This article advances a theoretical reconceptualization of youth councils by introducing the concept of adaptive civic infrastructure to explain how youth participation unfolds within community-based organizational contexts, specifically Refugee-Led Organizations. Existi...

AYURVEDIC APPROACH IN THE MANAGEMENT OF DIABETIC NEUROPATHY- A REVIEW

Background: Diabetes mellitus is a multifactorial disorder of metabolism which affects approximately 246 million people all over the world. According to WHO, India has been projected as the country with the fastest growing population of diabetic patients. Diabetic neuropathy is o...

Expression Analysis of microRNAs in Peripheral Blood Mononuclear Cells in Type 2 Diabetes

MicroRNAs (miRNAs) are involved in the regulation of glucose metabolism and inflammatory processes associated with type 2 diabetes (T2D) and have potential as biomarkers and therapeutic targets. We analysed the expression of miR-155-5p, miR-141-3p, miR-15b-5p, miR-18a-5p, and miR...

CFD–DEM Analysis and Field Evaluation of a Dual-Roller Fresh-Safflower Filament Harvester with Pneumatic-Assisted Separation

To achieve the efficient mechanized harvesting of fresh safflower filaments, this paper proposes a harvesting device using dual-roller gripping and pneumatic-assisted separation. According to the mechanical properties of fresh filaments, the meta-particle method is employed to co...

Local-to-rack-scale temperature responses of sodium heat pipes inserted into industrial graphitization-furnace insulation

Post-shutdown cooling of industrial graphitization furnaces is constrained by the large thermal inventory and low conductivity of packed petroleum-coke/graphite insulation. This study examines the local-to-rack-scale thermal response produced when sodium high-temperature heat pip...

A qualitative case study of school counselors-in-training omitting a suicide assessment

Using a qualitative case study, researchers explored the responses of three school counselors-in-training who did not conduct a suicide assessment within an experiential andragogical intervention of a first session with a recently transferred simulated student presenting in distr...

Put-Call Oranı ve Koşullu Getiri Tahmini: BIST30 Endeks Opsiyon Piyasasında Volatiliteye Bağlı Öngörü Gücü

Çalışma 2024/07 – 2025/07 dönemlerinde BİST Vadeli İşlemler ve Opsiyon Piyasası’nda işlem gören BİST30 endeksine dayalı opsiyon kontratlarında gerçekleşen işlemlerin BİST30 getiri endeksinin kısa vadeli getirilerini tahmin etme yeteneğini ölçmeyi amaçlamaktadır. Çalışmanın odağın...

Immobilized Neuroglobin Scavenges Carbon Monoxide From Circulating Carboxyhemoglobin

Carbon monoxide (CO) poisoning is responsible for around 50,000 emergency department visits per year in the United States alone. Currently, there is no available antidote for CO poisoning. We have previously developed an antidotal therapy based on an engineered hemeprotein, human...

Patient-Reported Tolerability, Treatment Initiation, and Discontinuation of Postoperative Progestin Therapy After Cesarean Scar Repair in Women Planning Pregnancy

Background and Objectives: Cesarean scar disorder (CSDi) may require surgical repair in women with a large niche and thin residual myometrium. At our center, temporary postoperative progestin therapy is recommended to suppress cyclic endometrial proliferation and menstrual activi...

Optimization of FFF parameters for enhanced tensile and shear strength of PLA + parts and mechanical performance of porous scaffolds

Fused filament fabrication (FFF) is widely used to produce polymer-based parts, particularly bioscaffolds, though mechanical performance depends heavily on process parameters. In the present study, a Taguchi L9 orthogonal design is used to examine the influence of printing angle,...

Topological Confinement and Energetic–Configurational Compensation at Nanoporous Silica Interfaces

Abstract Conventional descriptions of adsorption stability emphasize direct adsorbate–surface interactions, leaving the configurational consequences of three-dimensional nanoconfinement insufficiently resolved. Here, simulations reveal how nanoporous topology reorganizes energeti...

When passion breeds silence: How coworkers’ work passion elicits envy and employee silence in hospitality workplaces

While work passion is well-studied as an intrapersonal motivational construct, its interpersonal consequences for coworkers remain underexplored. Drawing primarily on the Social Functional Theory of Emotions, we examine how employees' observed work passion functions as a social s...

Machine Learning Approach for Cardiovascular Disease Risk Stratification Using Ensemble Classifiers and Dimensionality Reduction

Cardiovascular disease (CVD) remains a leading cause of morbidity and mortality worldwide, motivating data-driven tools that complement established clinical risk criteria. We present a two-pathway machine learning framework for CVD risk assessment. Pathway I is a brief rule-learn...

Synergizing physical and cognitive training toward active aging with mixed reality

The aging of the global population poses a growing challenge to healthcare systems, as increased longevity is often accompanied by progressive physical and cognitive decline. In the absence of disease-modifying treatments, Active Aging (AA) is promoted as a strategy to preserve a...

Novel 3D volumetric and gallium casting assessment of anterior clinoidectomy for microsurgical clipping of posterior communicating artery aneurysms: an anatomical laboratory study

Abstract Background Microsurgical treatment of dysmorphic, wide-neck posterior communicating artery aneurysms may require anterior clinoidectomy to improve exposure, proximal control, and clip maneuverability. Although many posterior communicating artery aneurysms are increasingl...

Earth-Abundant Manganese Catalysts for Dehydrogenative Coupling of Alcohols and Silanols with Hydrosilanes

Abstract The development of catalysts and/or simple systems based on earth-abundant metals that enable the selective synthesis of siloxanes and alkoxysilanes while generating valuable hydrogen as the sole byproduct remains a major challenge in catalysis. Herein, we report a mild,...

Estimating the threat of AI-agent responding across online survey platforms

Recent research and advances in LLMs have led to widespread concern that AI agents could pose as human online survey-takers. However, it remains unclear how prevalent AI agents are on survey research platforms and how to effectively detect AI agents. We validated a series of AI d...