Research works
The research papers we track — the newest first. Works with a plain-language summary link to it.
81853 work(s)
- BiologyOpen access
Cancer treatment faces severe challenges such as drug resistance, side effects, and high costs. The “repurposing old drugs” strategy, which involves repositioning approved drugs for non-oncology indications for cancer treatment, has opened up new avenues for developing efficient,...
- Society & EconomicsOpen access
Most organisations add a large language model to a product by sending each request to a model hosted by a third party. For a product that processes personal data, confidential records, or that falls within the high-risk category of the EU AI Act, that convenience carries three co...
- Society & EconomicsOpen access
Nail biting (onychophagia) is a common maladaptive oral habit among primary school pupils that, if left unaddressed, may result in dental complications, nail bed injury, social embarrassment, and reduced self-esteem. Despite its prevalence, primary schools in Awka Education Zone...
- Health & MedicineOpen access
Abstract Although some symptoms of Parkinson’s disease can be pharmacologically alleviated, stopping disease progression is not currently possible. Motor impairment in Parkinson’s disease is associated with accumulation of aggregates of the protein α-synuclein (α-syn) in dopamine...
- BiologyOpen access
Shockwave‐Induced Myoblast Exosome‐Like Vesicles: Emerging Drivers of Muscle Regeneration
ABSTRACT Exosomes, a subset of nanosized extracellular vesicles, are key mediators of intracellular communication that show growing therapeutic potential in skeletal muscle regeneration. By shuttling bioactive cargoes between cells, they modulate recipient cell behavior, influenc...
- Society & EconomicsOpen access
The company secretary occupies a constitutively important position within South Africa's corporate governance architecture. Yet both of the country's two principal governance instruments, the Companies Act 71 of 2008 (as amended) and the King V Code on Corporate Governance for So...
- BiologyOpen access
ABSTRACT The impact of immune checkpoint inhibitors combined with neoadjuvant chemotherapy (NAC) on surgical outcomes and immune remodeling remains underexplored. To investigate the efficacy and tumor immune microenvironment (TIME) changes of camrelizumab plus NAC for triple‐nega...
- Health & MedicineOpen access
AIMS: To determine the prevalence and characteristics of urinary catheter blockage in older patients using objective indicators and to characterize obstructive materials and microbiota. DESIGN: A cross-sectional study. METHODS: Patients aged ≥ 65 years with an indwelling catheter...
- BiologyOpen access
Abstract Background In view of new evidence revealing a mechanical and nociceptive role of the thoracolumbar fascia (TLF), it has been suggested to be involved in low back pain. Objective To compare characteristics of the TLF in low back pain (LBP) patients and asymptomatic contr...
- AI & Computing
Default vertical dashboard orientations in virtual reality (VR) lack systematic ergonomic validation across mainstream gestural interaction paradigms. This study compares four dashboard orientations (horizontal, 60° inclined upward, vertical, 60° inclined downward) under direct h...
- Health & MedicineOpen access
Intraluminal unicystic ameloblastoma is characterized by tumor proliferation confined to the cystic lumen, without invasion of the supporting connective tissue, a feature that has led some authors to regard it as particularly suited to conservative surgical treatment. Objective:...
- Engineering & TechnologyOpen access
Connected vehicles and vehicle-to-everything (V2X) communication create new opportunities for estimating urban origin–destination (OD) demand from continuously collected mobility data. However, in realistic deployment conditions, only a fraction of vehicles may be connected, maki...
- Engineering & TechnologyOpen access
Lignin pyrolysis is a sustainable pathway for synthesizing high-value alkylphenol chemicals and fuels. In this study, the co-pyrolysis process of lignin and spent bleaching clay was investigated for producing alkylphenols. The effects of different metal-loaded biochars, pyrolysis...
- Climate & EnvironmentOpen access
The aim of this study is to determine the age and depositional environment of the Harami Formation through an integrated interpretation of XRF, ICP-MS, SEM-EDS, stable isotope, and radioactive isotope analysis results and findings of larger benthic foraminifera. Findings from the...
- Health & MedicineOpen access
Abstract Cardiovascular disease (CVD) is a leading cause of morbidity and mortality among cancer survivors, driven by the cancer itself, its treatments, and shared risk factors. Despite numerous systematic reviews and meta-analyses, the evidence remains fragmented and inconsisten...
- AI & ComputingOpen access
Topology is one of the most important factors influencing the performance of software-defined wireless sensor networks (SDWSN) in the Internet of Things (IoT). This paper presents a novel topology control algorithm using federated reinforcement learning, proposed for SDWSN in the...
- BiologyOpen access
Background/Objectives: Multidrug-resistant (MDR) Pseudomonas aeruginosa pneumonia and bloodstream infections (BSI) remain challenging because of their severity, limited therapeutic options, and high mortality, despite the availability of novel β-lactam-based agents. We aimed to d...
- Society & EconomicsOpen access
Background/Objectives: Eating disorders (EDs) have historically been associated with young women, and their presence in older adults remains poorly recognized despite evidence that they can persist, recur, or emerge in later life. Primary care nurses are strategically positioned...
- AI & ComputingOpen access
When the 132 Hz base frequency of the E8 lattice is modulated by golden‑ratio phase shifts, the 240 root vectors undergo a non‑linear torsion that generates a 4D geometric spiral in information density. This phi‑coupled torsion stabilizes asymmetric Posner molecule (Ca₉(PO₄)₆) en...
- BiologyOpen access
Bis(2-ethylhexyl) phthalate (DEHP), a widely used plasticizer, is known to disrupt immune homeostasis through various mechanisms. This study investigated the protective potential of coenzyme Q10 (Q10) against DEHP-induced immunotoxicity in juvenile male Sprague-Dawley rats. A tot...