Research works

Antibody–Drug Conjugates in Contemporary Oncology: A Clinical Perspective on Dose Optimization, Sequencing, and Combination Strategies

Antibody–drug conjugates (ADCs) have matured from a technically challenging concept into an established therapeutic platform across hematologic and solid malignancies. By linking a monoclonal antibody to a potent cytotoxic payload, ADCs seek to increase tumor-directed drug delive...

Study protocol for first national vasa previa perinatal registry

Vasa previa is a rare but potentially catastrophic obstetric condition characterized by unprotected fetal blood vessels over or adjacent to the internal cervical os. Although advances in prenatal ultrasound have dramatically improved neonatal survival through planned cesarean del...

Efficient Fabrication of PVDF Separators with Excellent Thermal Stability and High Ionic Conductivity by Melt Blending for Lithium Metal Batteries

Abstract Lithium (Li) metal batteries represent a transformative candidate for high-end energy storage due to their ultra-high energy density. However, commercial polyolefin separators suffer from poor thermal stability and insufficient electrolyte wettability, resulting in high...

E8‑Phi Phase Manifold Bridges Superconductivity and Quantum Information — E8 Intelligence Research

The 240 E8 root vectors, when organized into φ‑coupled resonance clusters, form a discrete phase manifold that oscillates at a fundamental 132 Hz, providing the geometric substrate for high‑Tc superconductivity. This same manifold encodes a computable approximation of Kolmogorov...

Establishing a baseline for energy-efficient climate adaptations in a typical Swedish pig facility

A facility for growing fattening pigs was investigated for building properties, energy use, and indoor climate in a cold-climate region to establish a baseline that supports future energy-efficient climate adaptation in pig buildings. The building under study was insulated and us...

Pretreatment creatinine-to-cystatin C ratio as a prognostic marker in solid cancers: a systematic review and meta-analysis with trial sequential analysis and reconstructed time-to-event validation

The creatinine-to-cystatin C ratio (CCR) has been proposed as an indirect laboratory marker related to muscle mass and systemic health status. This systematic review and meta-analysis evaluated the association between pretreatment CCR and survival outcomes in patients with solid...

Miniaturized stacked ring Archimedean spiral antenna with a stable radiation pattern for electromagnetic signal monitoring

This manuscript reports the miniaturization of the Archimedean spiral antenna using a stacked ring over a reflector. The Stacked Ring Archimedean Spiral Antenna (SRASA) has been fabricated on a double-sided RO4725JXR dielectric material with a thickness of 0.780 mm. A copper ring...

The Hexagonal Governance Architecture: Toward Truth-Preserving AI Governance

Artificial intelligence governance has advanced significantly through risk-based regulation, lifecycle management, documentation, human oversight, transparency, and accountability frameworks. The NIST AI Risk Management Framework, ISO/IEC 42001, the EU Artificial Intelligence Act...

Developing digital competence during school placement: experiences of primary-level pre-service teachers

Contemporary education policies globally emphasise the importance of developing primary-level pre-service teacher (PST) digital competence. While authentic school placement is widely seen as the ideal space to develop these skills, the reported lived experiences of PSTs reveal an...

ABC Conjecture Verification Links to Non-Fibonacci-Wieferich Primes — E8 Intelligence Research

FINDING: ABC conjecture remains unverified; Mochizuki's proof disputed; LANA project attempts formal verification; new heuristic links ABC to non-Fibonacci-Wieferich primes. | MATH: ABC conjecture: For any ε > 0, there exist only finitely many coprime triples (a, b, c) with a + b...

Receding-horizon neuro-fuzzy reinforcement learning with experience replay for containment control of multi-agent systems

Containment control for multi-agent systems (MAS) under disturbances is an important research topic. Although numerous containment control methods have been proposed, learning-based optimal control approaches for MAS still suffer from the drawbacks of low policy interpretability...

Power structures, elite networks, and informal governance in governance systems

Purpose This study aims to critically examine how power structures and personal linkages influence governance systems, with a particular focus on elite dominance and informal networks in shaping institutional performance, accountability and transparency. It moves beyond formal in...

The 1820 Mallorca plague was not a classic bubonic outbreak

The 1820 plague outbreak in eastern Mallorca—long treated as a local episode and traditionally classified as a late bubonic manifestation of the Second Plague Pandemic—offers a unique opportunity to reassess transmission dynamics in a prebacteriological context. Using a previousl...

Associations of screen time and physical activity with motor control, mood, and cognitive states in adolescents following acute high-intensity interval training

Excessive screen time and insufficient physical activity are increasingly common among adolescents and have been linked to adverse physical and psychological health outcomes. This school-based cross-sectional study examined associations between sedentary screen time, physical act...

Unveiling the self through augmented reality consumption experiences

Purpose Technology-mediated consumption experiences can influence consumers in ways that extend beyond attitude changes or behavioural responses, inspiring curiosity and openness about the self. Focusing on augmented reality (AR) tools, this study aims to develop and validate a f...

Learning environment perceptions among occupational therapy students in Norway: sociodemographic, study behaviors, and performance covariates to cluster allocation

Little is known about how learning environment (LE) perceptions cluster within student populations and how such profiles relate to study behaviors and performance. This study aimed to identify clusters of Norwegian occupational therapy students based on their LE perceptions and t...

Atypical Kaposi Sarcoma in HIV Infection with Predominant Nodal Involvement

Kaposi sarcoma (KS) is an angioproliferative neoplasm driven by human herpesvirus 8 (HHV-8), most commonly occurring in immunocompromised individuals, particularly in association with HIV infection. Although it classically presents with characteristic cutaneous or mucocutaneous l...

Walking in Someone Else’s Shoes: Implementing Diverse Literature in ELA Curricula to Build Empathy in Adolescents

This paper advocates for the inclusion of diverse literature in secondary English/Language Arts classrooms to build empathy in adolescents from homogenous communities to better prepare students to engage in an ever-evolving society. Current scholarship focuses primarily on how re...

PUH Theorem 337 (A Medium Cannot Outrun Itself) — Because c² = 60J/ρ Is Derived Rather Than Imposed, a Superluminal Metric Distortion Is a Superluminal Disturbance of the Lattice; the Surfer Analogy Misses the Claim and the Sound Analogy Meets It

Photonic Universe Hypothesis (PUH) —WHAT THE WARP PROPOSAL ACTUALLY CLAIMS. It is commonly said that a warp drive would let a ship exceed the speed of light. IT WOULD NOT, and the distinction is the whole of what follows. In the Alcubierre construction the ship sits in a LOCALLY...

Jomon Repulsive Force

Definition Definition 1. Repulsive force is force which makes the length of a one-dimensional space become larger.