Research works
The research papers we track — the newest first. Works with a plain-language summary link to it.
76240 work(s)
- Biology
ABSTRACT The present study aimed to evaluate the effects of dimethylcurcumin (DMC) on copper sulfate (CuSO 4 )‐induced inflammatory toxicity in zebrafish, and preliminarily explore its potential molecular mechanism. Zebrafish larvae at 3 days post‐fertilization (3 dpf) were pretr...
- Society & Economics
This article introduces the concept of a "strategic industry organization" (SIO) for entities operating under state development programs with mandatory target indicators. It examines the specifics of change management during the digital transformation of SIOs during the transitio...
- Health & Medicine
c ‐Met/DDR1 Dual‐Target Tyrosine Kinase Inhibitor Featuring an Imidazo[1,2‐A]pyridine Core
In this contribution, we report the design, synthesis, and bioactivity evaluation of a novel class of dual‐target tyrosine kinases inhibitors (TKIs). By linking imidazo[1,2‐a]pyridines with a commonly used cyclopropanecarboxylic acid pharmacophore fragment, a number of novel pote...
- Physics & SpaceOpen access
Structural Origin of Cosmological Density Ratios: $\Omega_m^2 = 3\Omega_\Lambda \Omega_b$
This work investigates a simple algebraic relation among cosmological density parameters $$\Omega_m^2 \approx 3\,\Omega_\Lambda\,\Omega_b$$ suggested by representative late-time cosmological parameter estimates reported by Planck and DESI analyses. The framework uses the fixed st...
- Health & Medicine
Pyrimidine has become an important scaffold for designing anticancer drugs because of its planar aromatic structure, synthetic versatility, and ability to establish key interactions with its target. This heterocyclic scaffold is an essential component of nucleic acids and many bi...
- Physics & SpaceOpen access
Topological Quantum Gates with 5-Fold Symmetry from Non-Abelian Anyons — E8 Intelligence Research
FINDING: Non-Abelian anyon braid group representations generate unitary gates whose eigenvalues can include roots of unity tied to 72° rotations (5-fold symmetry), linking topological quantum computation to pentagonal/icosahedral structures. | MATH: Braid group \(B_n\) acts on fu...
- Health & Medicine
ABSTRACT Background and Aim Minocycline‐containing bismuth quadruple therapy may provide a practical option for Helicobacter pylori ( H. pylori ) rescue treatment when tetracycline is unavailable, yet the optimal dosing remains unclear. We aimed to compare the efficacy and safety...
- BiologyOpen access
Müoopia esinemissagedus: kas meil on põhjust muretsemiseks?
Müoopia ehk lühinägevus on kogu maailmas sageli esinev refraktsioonihäire. Globaalselt on müoopia esinemissagedus viimastel aastakümnetel märkimisväärselt suurenenud, ulatudes epideemilisele tasemele Ida- ja Kagu-Aasias. Maailma Terviseorganisatsiooni (WHO) ja Brien Holden Vision...
- AI & ComputingOpen access
FINDING: Chern-Simons theory links knot invariants to topological strings via mirror symmetry and derived categories of coherent sheaves on Calabi-Yau threefolds. MATH: - Chern-Simons action: \( S_{CS} = \frac{k}{4\pi} \int_M \text{Tr}(A \wedge dA + \frac{2}{3} A \wedge A \wedge...
- Health & MedicineOpen access
The American Board of Internal Medicine Research Pathway (ABIM RP) is designed to train physician-scientists by shortening postgraduate clinical training and increasing research time. We surveyed ABIM RP graduates to understand career trajectories, research engagement, and barrie...
- AI & ComputingOpen access
Provenance, Authenticity, and Copyright Enforcement in the Age of Synthetic Media
Synthetic media is no longer a theoretical concern. We are living through a quiet but seismic shift in how creative work is made, and the law is struggling to keep pace. Deepfakes, AI-generated images, fabricated audio, algorithmically written text. It is everywhere, and the inte...
- AI & ComputingOpen access
The Topological and Categorical Stack of Functor Reasoning Models
This note organizes the current mathematical architecture of Functor Reasoning Models (FRMs). The construction begins with a metric topology on tokens, passes through finite-dimensional local representations whose linear maps compose by matrix multiplication, and places an intrin...
- Society & EconomicsOpen access
This document is the definitive macro‑structural analysis of the United Kingdom’s long‑term decline, anchored to the behaviour of its most sensitive economic constant: the Freddo Price Index (FPI). Through formal modelling, cross‑domain mapping, and scalar‑field interpretation, t...
- AI & ComputingOpen access
This technical note examines version 1 of Guth, Wang and Zahl, A streamlined proof of the Kakeya set conjecture in R^3 (arXiv:2601.14411v1). It records parameter and bookkeeping defects in Theorem 7.3(B), supplies a self-contained proof of the omitted shaded slab estimate in Lemm...
- Health & Medicine
Penile metastasis from rectal cancer: a case report
Penile metastasis is extremely rare despite the rich vascularization of the organ. The majority of metastatic lesions originate from adjacent genitourinary and pelvic organs, particularly the bladder, prostate, and rectosigmoid colon (28.6%, 27.9%, and 12.2%, respectively). In ad...
- Health & MedicineOpen access
Background: Oral potentially malignant disorders (OPMDs), particularly oral leukoplakia and oral submucous fibrosis (OSMF), are associated with an increased risk of malignant transformation. Lactate dehydrogenase (LDH), an intracellular glycolytic enzyme released during cellular...
- Materials & EnergyOpen access
ABSTRACT Electrocatalytic N─N oxidative coupling (OC) offers an eco‐friendly approach to produce value‐added azo materials, but suffers from sluggish kinetics and limited Faradaic efficiency (FE). The key fundamental issue is unfavorable competitive adsorption of hydroxyl groups...
- Society & Economics
Dağıtım ve risk yönetimi; tedarik zinciri yönetiminin etkinliği açısından iki önemli kavramdır. Tedarik zinciri yönetimi bağlamında dağıtım süreçleri; taşıma, depolama, envanter yönetimi, siparişin gerçekleştirilmesi, dağıtım ağı tasarımı gibi temel unsurlardan oluşmaktadır. Dağı...
- Biology
Aminosulfine‐Based Donor Platform for Controlled Release of Sulfenic Acid (HSOH)
ABSTRACT Reactive sulfur species derived from hydrogen sulfide are central regulators of redox signaling; however, sulfenic acid (HSOH) has remained largely inaccessible owing to the absence of chemically defined donor systems. Here we report a mechanistically delineated strategy...
- AI & ComputingOpen access
AI Model Sharing Economy: Designing Royalty Structures for Distributed Model Usage
Research article: AI Model Sharing Economy: Designing Royalty Structures for Distributed Model Usage