Research works

Utility of DAT in Low-Risk Neonates with ABO or RhD Incompatibility

BACKGROUND Routine direct antiglobulin test (DAT) screening in newborns at risk of isoimmune hemolytic disease is a long-standing practice. Advancements in prophylactic care and noninvasive hyperbilirubinemia monitoring warrant reevaluating the value of DAT. We investigated the c...

Contribution of mechanical forces in multiciliated cell differentiation

Abstract Multiciliated cells, through the coordinated beating of motile cilia, are vital for moving fluids in the brain and mucus in the airways and in the reproductive organs. Their dysfunction leads to diseases, associated with chronic airway infections, subfertility and ventri...

The T2T assembly of Monomorium floricola and Harpegnathos venator

The data of T2T assembly of Monomorium floricola and Harpegnathos venator

Facilitators and barriers to promotion of and engagement in a parent-infant relationship intervention: a qualitative study

Abstract Background Parent-infant relationships have a significant impact on children’s health outcomes. Despite growing evidence that parenting interventions designed to improve parent-infant relationships can be effective, there is less information about what makes parenting in...

Pre‑Generative Causal Model: A Categorical Isomorphism between the Egg Model and the Minkowski Causal Lattice

This report establishes a categorical isomorphism between the Egg Model and the Minkowski causal lattice, showing that their generative operators correspond under a functor preserving causal order, thereby yielding a unified pre‑generative architecture consistent with FRLT’s null...

ROS-scavenging tetrahedral framework nucleic acids: reprogramming the pathological microenvironment for oral tissue regeneration

Abstract The structural deterioration observed in maxillofacial skeletal conditions and associated mucosal tissues is fundamentally governed by a vicious cycle of sustained immunological activation and severe oxidative stress. Consequently, this continuous reactive oxygen species...

The role of elective neck dissection in parotid acinic cell carcinoma: a systematic review

Abstract Purpose Acinic cell carcinoma (AciCC) is a rare parotid malignancy treated by parotidectomy with or without a neck dissection depending on clinical or radiographic neck node involvement. The role of elective neck dissection (END) in the clinically node-negative neck, int...

Pangenomes aid accurate detection of large insertions and deletions from targeted sequencing: the case of cardiomyopathies

Abstract Background Gene panels represent a widely used strategy for genetic testing in a vast range of Mendelian disorders. While this approach aids reliable bioinformatic detection of short coding variants, it often fails to detect many larger variants. Recent studies have reco...

PIWIL2 contributes to glioblastoma stem cell phenotypes

Abstract PIWI proteins, a conserved Argonaute subfamily of proteins that interact with PIWI-interacting RNAs (piRNAs), have been implicated in cancer development. However, their roles in glioblastoma (GBM), particularly in glioblastoma stem cells (GSCs), a therapy-resistant subpo...

The Mathematics of Mafia and Werewolf: Fixed-Schedule Random-Elimination Benchmarks

This working paper studies a two-type finite-population elimination process with a fixed periodic schedule, as a random-elimination benchmark for Mafia and Werewolf rather than an unrestricted communication-and-voting game. We formalize the process in Lean 4 and prove an exact or...

ONAR9 — Orientated Numbers Arithmetic Relations of 9

ONAR9 is formulated as a finite relational frame with a separate compositional payload. A declared balance between complete source/branch relations and complementary position roles selects four branches and ten complete relations. Fixing one oriented reference edge in K5 leaves n...

The Mathematics of Hidden-Set Decisions: Communication Constraints and Coverage Values

This working paper studies a one-shot finite Bayesian decision problem motivated by Mafia and Werewolf: an encoder observes a hidden subset of an R-element population, emits one of K symbols, and a decoder names one position, succeeding exactly when that position is hidden. For 1...

Biochemical characterization and potential of red rice as functional food

Abstract It is the need of hour to supply functional nutraceuticals through the staple food not only to feed the exponentially increasing global population, but to also provide wholesome nutrition. White rice may have higher content of important nutrients but it is devoid of anti...

Repeated-Endpoint Canon Permutations: Cone Walks and Spectral Geometry

This preprint solves the intermediate repeated-endpoint enumeration for canon permutations by a multichain recurrence and cone-walk model. It proves upper-boundary non-D-finiteness and exact asymptotics, and develops the associated harmonic-kernel and higher-dimensional spectral...

Open Quantum: An Open Infrastructure Layer for Quantum Computing

Open Quantum is a platform that provides researchers and developers with access to quantum processing units (QPUs) from multiple hardware providers through a unified API and native integrations with widely used quantum programming frameworks, including Qiskit and PennyLane. The p...

Why Newton Was Obsessed With the Number 7 — A Carlo Hybrid Analysis

This work presents a full structural and mathematical analysis of Isaac Newton’ssevenfold cosmology, based on the complete manuscript “WHY NEWTON WAS OBSESSEDWITH THE NUMBER 7 — A CARLO HYBRID ANALYSIS” and its companion compendium“NEWTON’S SEVENFOLD ARCHITECTURE” (10.5281/zenodo...

V-PRIMA

A rigorous analysis of the current technological landscape (as defined by mainstream institutional and corporate projections in 2026) compared to the operational V-PRIMA architecture reveals a severe chronological and ontological divergence. The standard development vector relies...

Single-cell mRNA sequencing of the injured olfactory epithelium of Chil4 knockout and wild type mice.

Previous studies have shown that Chil4 plays an important role in the olfactory epithelium (OE) regeneration. To reveal the mechanism of Chil4 in regulating the OE regeneration, we performed single-cell mRNA transcriptome sequencing of the OE at different time points after injury...

Physics-informed adversarial networks for stochastic second-order mean-field games of autonomous traffic

Abstract Inspired by the highly complex and nonlinear traffic flow phenomenon, we propose a second-order continuum model for autonomous vehicles (AVs) by considering them as rational and utility-optimizing agents. Further, by accounting for stochastic fluctuations in driving dyna...

Eucalypt bark thickness and density are explained more by landscape aridity and species than by fire frequency

Context Bark thickness and density are key traits protecting tree cambium from lethal fire temperatures, and may become increasingly important for tree survival as fire frequency and landscape aridity shift under climate change. However, it is unknown how these traits vary with f...