Research works
The research papers we track — the newest first. Works with a plain-language summary link to it.
85923 work(s)
- Health & Medicine
Summary The heterogeneity of multiple myeloma (MM) significantly impacts treatment outcomes. Myeloma risk profile (MRP), introduced by the UK Myeloma Research Alliance, is a novel prognostic model for patients with transplant‐ineligible newly diagnosed MM (TIE‐NDMM) utilizing eas...
- Materials & Energy
Room-Temperature C–C Bond Cleavage and Ring Expansion of Benzene by a Copper(I)-Substituted Silylene
Abstract The cleavage and functionalization of benzene C–C bonds under mild conditions is of fundamental interest yet remains challenging. Herein, we report that an in situ generated copper(I)-substituted silylene undergoes reversible insertion into benzene at room temperature, a...
- Engineering & TechnologyOpen access
Solar thermal energy storage systems play a vital role in bridging the gap between intermittent solar availability and continuous energy demand; however, their efficiency is severely constrained by the inherently low thermal conductivity of phase change materials. Integrating phy...
- Health & Medicine
Microscopic Dynamic Mechanisms of Surfactant-Induced Skin Irritation
Abstract Surfactants are essential components of detergents and personal care products due to their unique amphiphilic structure. However, the mechanism underlying surfactant-induced skin irritation remains unclear. This study systematically combined experiments with molecular dy...
- Materials & Energy
Abstract The modulation of ferromagnetic order in 2D carbon materials has attracted increasing attention for the development of next-generation spintronic devices and multifunctional information storage technologies. In particular, the graphdiyne (GDY) family has been regarded as...
- Climate & EnvironmentOpen access
The Potential Inhibitory Effect of Copper and Nickel on Gaseous Soil N Emissions
Nickel (Ni) and copper (Cu) are essential soil micronutrients that are beneficial for plant growth and development when applied at the right levels to deficient soils. However, they can also be of concern if excessive application leads to accumulation in soil, causing soil fertil...
- Biology
Cell-to-Cell Signaling Networks at the Blood-Brain Barrier in Health and Disease
The blood-brain barrier (BBB) is a highly specialized interface between the central nervous system and the peripheral circulation, crucial for maintaining neuronal homeostasis and protecting the brain parenchyma from potentially harmful blood-borne substances. This review examine...
- Climate & EnvironmentOpen access
Abstract Poyang Lake, China's largest floodplain lake, plays a crucial role in regional hydrology by seasonally regulating water to mitigate floods and sustain extensive wetland ecosystems. However, complex hydrodynamics and significant spatial hydraulic gradients often invalidat...
- Society & EconomicsOpen access
ZUNGUNG-P: An Open Narrative Engine Exploring the Possibilities of Genre Flexibility and Hard Worldbuilding. Zungung-P is a worldbuilding project set within the fantasy and low-fantasy genre, aimed at exploring the capabilities of hard worldbuilding, meant to showcase a propriate...
- Health & MedicineOpen access
Abstract Introduction Deprescribing is the planned withdrawal or dose reduction of medicines when harms outweigh benefits or when they are no longer required. Following publication of the Clinical Practice Guideline for Deprescribing in Older People in September 2025, supporting...
- BiologyOpen access
This paper develops a transformation framework connecting structural and spectral-temporal representations of governance within a generative-relational approach. Building on two previously distinguished representational coordinates, Type-I governance describes intervention throug...
- Biology
Acupuncture Improves Poststroke Cognitive Impairment by Regulating the miR-18a-5p
Background Poststroke cognitive impairment (PSCI) severely impacts patients’ lives. Acupuncture shows potential in improving PSCI, yet the molecular mechanism remains unclear. Aims This study aimed to investigate the potential efficacy of acupuncture in alleviating PSCI symptoms...
- Health & MedicineOpen access
Cardiovascular-kidney-metabolic (CKM) syndrome and cardiometabolic multimorbidity (CMM) carry substantial mortality, yet whether a composite index integrating insulin resistance and frailty shows stronger associations with advanced CKM syndrome, CMM, and mortality than convention...
- Climate & Environment
Abstract This paper proposes a substantial refinement of the regional stratigraphic scheme of Upper Neopleistocene loess deposits in the central East European Plain. The Aleksandrov quarry is considered as the main stratotype section of the late Neopleistocene. A variety of moder...
- Climate & EnvironmentOpen access
Abstract In 2022, a lidar survey of the Three Rivers Region, conducted by the Belize Estates Archaeology Survey Team, identified multiple previously unrecorded sites, including Tiho’witz, located between and atop five hills ranging in height from 7 m to 18 m. Our 2023 ground trut...
- BiologyOpen access
The urinary pathobiont Actinobaculum massiliense can generate androgens via the dirAB pathway
While overlooked during the Human Microbiome Project, characterizing the urinary microbiota in health and disease is a new frontier in microbiome science. Recent studies have associated differential abundance of bacterial taxa including Propionimicrobium lymphophilum and Actinoba...
- Engineering & TechnologyOpen access
This study demonstrates binder‐free laser powder bed fusion (PBF‐LB) of 8 mol% yttria‐stabilized zirconia (8YSZ) using a femtosecond laser and a triangular scan strategy that controls heat accumulation by varying scan‐vector length. Laser power (31–52 W), scan speed (100–500 mm s...
- Health & MedicineOpen access
Background: Glioblastoma (GBM) remains the most aggressive primary brain tumour with a dismal prognosis despite multimodal therapy. The optimal duration of adjuvant temozolomide (TMZ) remains debated. Methods: A retrospective analysis was conducted on 110 histologically confirmed...
- Health & Medicine
Background: Extended post antibiotics do not reduce infectious complications after traumatic facial injuries or elective clean-contaminated head and neck operation. However, the optimal duration of antibiotic prophylaxis following operative repair of traumatic neck aerodigestive...
- Health & MedicineOpen access
Abstract The salivary glands of hematophagous arthropods possess a remarkable molecular diversity, reflecting evolutionary adaptations to blood feeding lifestyle and vector-host interactions. In this study, we characterized the salivary-gland transcriptome of adult female Simuliu...