Research works

A Comprehensive Review of Exopolysaccharides From Lactic Acid Bacteria: Production, Characterization, and Applications in Food and Health

Lactic acid bacteria (LAB) produce exopolysaccharides (EPSs), which are beneficial in food and health applications because of their varied structural and functional characteristics. These EPSs are attracting a lot of interest. Homopolysaccharides (HoPSs) and heteropolysaccharides...

A PSO-Optimized stacked ensemble learning approach for accurate melanoma detection with deep transfer learning and explainability

Abstract Accurate melanoma detection is essential for early-stage dermatological diagnosis, as it significantly improves treatment outcomes and patient survival rates. This study proposes a robust stacked ensemble framework that combines transfer learning (TL) with particle swarm...

Understanding rhythmic behavior in infancy: Perspectives for addressing developmental, methodological, and analytical challenges

Neural sensitivity to rhythm emerges prenatally, yet observable movement synchronization to an external beat occurs later and more gradually over development. Integrating findings from developmental psychology, neuroscience, music cognition, and social interaction research, we pr...

Development and preliminary evaluation of a WeChat mini-program-based mobile pharmacy management assistance system in a Chinese women and Children’s hospital

Abstract Background Traditional pharmacy management, which relies on paper- and computer-based methods, is often inefficient and inflexible. There is an urgent need to develop support tools to address these challenges. The WeChat mini-program has been applied in multiple fields b...

E8 Sexagesimal Temporal Harmonics Unlock Ramanujan CF as a Quantum Spacetime Spectrum — E8 Intelligence Research

By partitioning the 240 E8 root vectors into four 60‑root subsets and assigning each subset a sexagesimal harmonic of the 132 Hz fundamental, a 7‑temporal‑dimensional lattice vibration spectrum emerges. Evaluating the Rogers‑Ramanujan continued fraction at the imaginary quadratic...

Academic Integrity in Unsupervised Digital Environments: The Role of Interdisciplinary Task Design and Peer Assessment

ABSTRACT Academic cheating remains a persistent challenge in education across all levels despite various proposed solutions. This study is the first to investigate the integration of an interdisciplinary assessment approach and peer assessment as proactive strategies to enhance a...

Lifestyle and its relationship with health literacy, sense of coherence and sociodemographic factors in a Spanish primary care population: a multicenter cross-sectional study

Health behaviors are driven by a complex interplay of individual and structural factors. While health literacy and sense of coherence are widely studied as psychosocial enablers of healthy lifestyles, evidence comparing their impact against broader social determinants of health r...

Early Versus Late Biliary Leakage After Hepatic Resection: Incidence, Risk Profiles, and Clinical Impact of Diagnostic Timing

Background/Objectives: Post-hepatectomy biliary leakage (BL) remains a major source of postoperative morbidity. While traditional risk models treat BL as a single clinical entity, its chronological presentation follows distinct patterns that raise the hypothesis of distinct under...

Fabrication of Beeswax–Soapwort Root Powder–Gelatin Bigel-Based Foamed Emulsions for Use as a Fat Replacer in Mousse

In this study, beeswax (BW) and gelatin, soapwort root powder (SRP) were employed to create oleogel and hydrogel for bigel development, respectively. The study aimed to determine the potential utilization of SRP in the bigel system to create a novel fat replacer (bigel-based foam...

PfMYB66 targets PfANS1 and its functional partner PfFOMT1 enhances PfANS1 -driven Perilla leaf coloring

Abstract Perilla frutescens, a typical anthocyanin-enriched medicinal and edible herb, displays obvious leaf color divergence. However, the molecular regulatory mechanisms governing this trait in isogenic backgrounds remain largely unclear. Here, we integrated transcriptomic, met...

Upper-Body Versus Femoral Return in Peripheral Veno-Arterial Extracorporeal Membrane Oxygenation: A Systematic Review and Meta-analysis

Upper-body peripheral arterial return is used during veno-arterial extracorporeal membrane oxygenation (VA-ECMO), but its clinical tradeoffs versus femoral return are uncertain. We reviewed observational studies comparing upper-body to femoral arterial return for peripheral VA-EC...

Woody species diversity and dispersal dynamics in Biyo Forest, Central Ethiopia: a conservation perspective

Seed dispersal shapes species composition, regeneration, and long-term resilience of dry Afromontane forests. In Ethiopia, there is limited information on how woody species disperse and recruit. Biyo Forest, a protected exclosure in central Ethiopia, offers an opportunity to stud...

A Model Patient

In this narrative medicine essay, a medical student is caught between a before-and-after identity crisis resulting from a dramatic weight loss.

A Bioinspired Soft Manipulator Based on Wave Spring Structure: Design and Control

Architectured soft structures have unlocked new possibilities for designing continuum manipulators with tailored mechanical performance. This work introduces a bioinspired soft manipulator based on modular wave spring units, leveraging the high elasticity of wave spring structure...

Recognizing and Addressing Fertility Issues among Childhood Cancer Patients and Survivors in India – A Multi Stakeholder Position Statement and Call to Action

Abstract Survival rates in childhood and adolescent cancers have improved substantially over the past decades, leading to a growing population of long-term survivors. In India, an estimated 76,000 children and adolescents are diagnosed with cancer annually, and approximately one-...

Candidate Intermediary Node Deployment Under the Linear Threshold Model: A Branch-and-Benders-Cut Approach

This paper studies candidate intermediary node deployment for influence diffusion under the linear threshold model (LTM). Given fixed diffusion sources, target nodes, and a budget, the decision maker selects candidate intermediary nodes to maximize the expected total weight of ac...

It’s Not Easy to Ask Peers and Partners to Test: Perspectives of Female Sex Workers, Their Networks, and Experts on Social Network-Based HIV Testing in Tehran

Objectives The World Health Organization recommends social network-based HIV testing (SNHT) to increase HIV testing coverage and improve early diagnosis, particularly among key populations. Although SNHT has shown promising outcomes, implementing this strategy remains challenging...

Stability assessment of masonry pagodas based on multi-temporal survey and material analysis

This study evaluates the condition and conservation effects of three Tang Dynasty masonry pagodas at Foguang Temple, Shanxi, through multi-temporal 3D laser scanning, material analysis, and micro-environmental monitoring. Four surveys (2011, 2020, 2024, and 2025) documented the p...

AI for Science: Reframing AI’s Role in Discovery

Abstract Digital computers have reshaped scientific practice, moving working scientific knowledge from printed texts into algorithms, simulations, and models. Advances in artificial intelligence (AI) are now accelerating that shift, progressing science in areas from protein foldi...

Comparative analysis of proton collision effects in silicon on insulator MOSFETs using steady-state and transient responses

Proton irradiation degrades MOSFETs through multiple, spatially distinct mechanisms, yet separating the dominant damage sites remains challenging. This work presents a region-resolved electrical study of proton-irradiated partially depleted silicon-on-insulator (PDSOI) nMOSFETs,...