Research works

Non-invasive sampling reveals distinct HPV and immune signatures associated with abnormal cytology in people living with HIV

Abstract Persistent high-risk HPV infections drive most anal cancers, disproportionately affecting people with HIV (PLH), for whom cytology-based screening remains essential. However, the biological context of abnormal anal cytology, particular regarding local immune cells, is in...

Climate change reshapes the potential transmission risk of human alveolar and cystic echinococcosis in western China: a projection based on MaxEnt models

BACKGROUND: Echinococcosis, a severe zoonotic parasitic disease, imposes a significant health burden in western China, primarily as alveolar (AE) and cystic (CE) forms caused by Echinococcus multilocularis (Em) and E. granulosus sensu lato (Egsl), respectively. Its transmission,...

The Oceanic Signature in Diamond: From Hydrothermal Alteration to Defect Architecture

Diamonds provide exceptionally durable records of geological processes occurring within Earth’s mantle, preserving information through mineral and fluid inclusions, isotopic compositions, growth structures, impurities, and lattice defects. Increasing evidence demonstrates that al...

cTIRF: TIRF-Like Computational Optical Sectioning for Widefield Fluorescence Microscopy

Abstract The resolving ability of widefield fluorescence microscopy is fundamentally limited by out-of-focus background owing to its low axial resolution, particularly for densely labeled biological samples. Although total internal reflection fluorescence (TIRF) microscopy provid...

Thick and Thin Globality: A Categorical Interpretation via Dictionary Sheaves and Sparse Selection

This paper contrasts thick globality from colimit gluing with thin globality from sparse selection in dictionary sheaves. We formalize selection as a right adjoint and show L1 regularization realizes this structure.

The Significant Push and Pull Factors Responsible for Migration of Africans (JAPA) Syndrome: The Comparative Analyses

This study investigates the endogamous and exogamous variables that represent African migration and the contemporary Nigerian Japa Syndrome. It contends that, beyond the unfavourable economic climate and the lingering security issues, among other internal vices in Africa, especia...

Passivation-Dependent Device-Level Thermal Robustness of Indium Gallium Oxide Thin-Film Transistors under Dynamic Random-Access Memory Relevant 600 °C Nitrogen Annealing

As conventional silicon-based dynamic random-access memory (DRAM) approaches its physical and electrical scaling limits, oxide semiconductors have emerged as promising channel materials for next-generation memory devices because of their low off-state current and process compatib...

(Short Paper16) Super-Intercellular Synchronization and High Light Adaptation in 4-Cell Green Alga Tetrabaena: A Spatially Extended Quantum Computing Model via a 4-QPU Array

Tetrabaena socialis, a four-celled colonial green alga arranged in a planar square, exhibits hydrodynamically synchronized swimming despite each cell possessing autonomous flagella. Furthermore, unlike related species that execute phototactic avoidance migrations under intense li...

Scale-Dependent Disformal Dark Matter: Resolving Cosmic Tensions with S-Matrix Positivity and Gravitational Wave Invariance

We present a fully covariant, scale-dependent disformal coupling within the dark sector (SD-DDM) designed to simultaneously resolve the Hubble (H0) and clustering (S8) tensions. By strictly confining the Bekenstein disformal transformation to Cold Dark Matter (CDM) and preserving...

hPSC-derived cardiac cell- and their combination-therapy for infarcted NHP hearts

RNA sequencing (RNA-seq) was performed on border zones collected in control, hCVPC, hCM, and Mix groups at 90 days post-MI .

Regulating Hard Segment Aggregation in Polyurethane Elastomers via Multiple Hydrogen Bonding Motifs for Enhanced Mechanical Properties

Abstract Controlling aggregation of soft and hard segments is a prevalent strategy to improve the mechanical performance of polyurethane elastomers, yet the regulatory actions of hydrogen bonding motifs governing the size and spatial distribution of hard and soft segments remain...

Tuning the Anticancer Activity of Gold(I) Complexes via Redox-Active Ar-Bian Ligands: Experimental and Theoretical Insights

Abstract A series of cationic gold(I) complexes of the type [Au(PPh3)(Ar-Bian)](CF3SO3) based on 1,2-bis[(2,4,6-trimethylphenyl)imino]acenaphthene (tmp-Bian), 1,2-bis[(4-chlorophenyl)imino]acenaphthene (4–Cl-C6H4–Bian), 1,2-bis[(4-bromophenyl)imino]acenaphthene (4–Br-C6H4–Bian),...

Winter activity and virus infection of Culicoides biting midges (Diptera: Ceratopogonidae) in German livestock housing before and during the 2024 BTV-3 outbreak

BACKGROUND: Despite its importance for Culicoides-borne disease risk assessment, the winter activity of species of this biting midge genus remains poorly characterized. Moreover, information on virus circulation in winter-active Culicoides vectors, both under endemic conditions a...

Guard cell Signal Transduction Mechanisms Controlling Stomatal Movements by Light, Abscisic Acid, CO2, VPD and Heat

Guard cell pairs form dynamic stomatal gas exchange pores in aerial tissues of plants. Guard cells regulate CO2 influx and water loss through stomata by integrating multiple environmental and internal signals. Guard cells serve as highly specialized sensory and signal processing...

High-fidelity update method for multi-temporal point cloud models with semantic-geometric collaborative constraints

Abstract Local incremental updating of point cloud models remains a core challenge in urban digital governance, limited by two well-documented bottlenecks: inaccurate semantic boundary localization and pronounced seam artifacts in texture stitching across fused regions. To addres...

Integrating Machine Learning Approaches and Topological Indices for Prediction of Electronic Properties in Anticancer Drugs

Abstract In this study, machine learning was used to predict electronic properties of anticancer drugs using molecular descriptors. Four machine learning models were employed to understand and predict the relationship between molecular structure and properties of the molecules. T...

Clinical outcomes before and after the introduction of clazosentan in aneurysmal subarachnoid hemorrhage: a multicenter retrospective study of clipping and endovascular treatment

OBJECTIVE: Definitive treatment for aneurysmal subarachnoid hemorrhage (aSAH) includes microsurgical clipping and endovascular treatment (EVT). In randomized trials such as ISAT and BRAT, EVT showed superiority in short-term outcomes and comparable or favorable long-term results....

How Later SEC Comparatives Leak Into Historical Backtests: A CoreWeave Case Study

This reproducible case study examines how later SEC comparative values can leak into an earlier historical backtest when a financial-data warehouse destructively retains only the latest value for each issuer, taxonomy concept, unit and fiscal period. The study matches 14 CoreWeav...

Real Pantheon+(N=1,701) Observational Test of Cosmological Special and General Relativity(CSTR/CGR):Full-Covariance MCMC, z-cut Bulk Flow Verification, and Statistical Model Selection as a Consistency Test

We present a rigorous real-data test of Cosmological Special Relativity(CSTR) and Cosmological General Relativity(CGR) versus Lambda CDM using Pantheon+SH0ES N=1,701 SNe Ia.

Time-of-Use Pricing Enhances Vehicle-to-Grid Benefits for Power Systems and Vehicle Owners but May Undermine Decarbonization

Abstract Vehicle-to-grid (V2G) is an important flexibility management technology for lower-carbon transport and the electricity grid. However, its effectiveness relies on the temporal alignment between the price incentives and grid dynamics. To overcome the challenge of coordinat...