Research works
The research papers we track — the newest first. Works with a plain-language summary link to it.
32986 work(s)
- AI & ComputingOpen access
MACHINE LEARNING IN PHARMACEUTICAL FORMULATION DEVELOPMENT
The use of ML algorithms in pharmaceutical research has enabled remarkable progress, especially by circumventing the problems inherent in the trial and error method of drug development. This review is intended to highlight the growing use of machine learning algorithms such as ar...
- Health & MedicineOpen access
DEVELOPMENT OF HPMC-BASED MATRIX TABLETS FOR THE SUSTAINED RELEASE OF METFORMIN HYDROCHLORIDE
537 million individuals globally are affected by type 2 diabetes mellitus (T2DM) India has the highest number of cancer cases worldwide. Metformin Hydrochloride is classified as a biguanide of BCS Class III. It is the first oral agent used to treat diabetes. Side-effects of this...
- Health & MedicineOpen access
A REVIEW ON FORMULATION AND EVALUATION OF TOPICAL GEL OF CLINDAMYCIN FOR ACNE VULGARIS
Acne vulgaris is one of the most common chronic inflammatory skin disorders affecting adolescents and adults worldwide. It develops due to excessive sebum production, follicular hyper keratinizati on, bacterial colonization by Cutibacterium acnes, and inflammation. Topical drug d...
- Health & MedicineOpen access
INTRODUCTION: Hypothyroidism is a hypo-metabolic state resulting from inadequate secretion of thyroid hormones. It is the second most common endocrine disorder among women and leading cause of menstrual abnormalities in all age group. Levothyroxine is the standard lifelong mode o...
- Health & MedicineOpen access
The domestication and cultivation of plants have been integral to human civilization since ancient times. In Ayurveda, Vrikshayurveda represents the traditional science of plant health and sustainable cultivation. Among its classical texts, Sharangadhara Paddhati (13th century CE...
- Health & MedicineOpen access
IBUPROFEN-LOADED CORE-SHELL NANOPARTICLES FOR OSTEOARTHRITIS: A REVIEW
Core-shell nanoparticles present a revolutionary approach in local nanomedicine, featuring highly adjustable physicochemical structures. The advanced bimodal nanoparticles contain a specifically designed hydrophobic core for the encapsulation and molecular stabilization of the th...
- Health & MedicineOpen access
Background: Aceclofenac is a non-steroidal anti-inflammatory drug (NSAID) widely used for the treatment of rheumatoid arthritis, osteoarthritis, and other inflammatory conditions. However, its oral administration is associated with gastrointestinal irritation, first-pass metaboli...
- Health & MedicineOpen access
FORMULATION AND EVALUATION OF IMMEDIATE-RELEASE OFLOXACIN TABLETS PREPARED BY WET GRANULATION METHOD
The present study was undertaken to formulate and evaluate immediate-release (IR) tablets of Ofloxacin using the wet granulation method. Six formulations (F1–F6) were prepared with different concentrations of pharmaceutical excipients to obtain tablets with satisfactory physicoch...
- Health & MedicineOpen access
Type 2 diabetes mellitus is the 7th leading cause of death in United States of America. One way by which this disease can be managed is through the use of hypoglycemic drugs. This study aims to investigate the effects of some hypoglycemic drugs such as Biguanide (metforming), sul...
- Health & MedicineOpen access
The present study was carried out to evaluate the antihelmintic activity of aqueous leaf extracts of Carica papaya and Tinospora cordifolia individually and in combination using Pheretimaposthuma as an experimental model. The extracts were prepared using the aqueous maceration me...
- Health & MedicineOpen access
FORMULATION AND EVALUATION OF COLLAGEN-BASED QUERCETIN CREAM
Background: Inflammation is a fundamental pathophysiological feature in numerous chronic diseases including arthritis, dermatitis, and wound-related conditions. Synthetic anti-inflammatory agents, though effective, are associated with significant adverse effects such as gastroint...
- Health & MedicineOpen access
Background: Pediatric hepatic hydatid disease is a major health problem in various regions. The concurrent pulmonary involvement in children is considered common and increase the postoperative risk. In our study assessed if pulmonary co-involvement independently predicts surgical...
- Health & MedicineOpen access
Oral diseases, including dental caries, plaque, gingivitis, and halitosis, are among the most prevalent health problems worldwide. Although conventional toothpastes effectively maintain oral hygiene, prolonged use of products containing synthetic chemicals may be associated with...
- BiologyOpen access
TRIVIDHA CHIKITSA: FROM SACRED PETALS TO PRACTICE IN STREE ROGA AND PRASUTI TANTRA
Introduction: Flowers possess unique therapeutic qualities that make them highly suitable for women’s healthcare. Their natural origin, gentle action, and compatibility with the female body enable their safe use across different stages of life, including adolescence, reproductive...
- Health & MedicineOpen access
INTRANASAL GEL TO TREAT PARKINSON DISEASE
Parkinson disease the second most common neurodegenerative disease caused due to the degeneration of dopaminergic neuron in substantial nigra results in the depletion of striatum dopamine.[1] The symptoms of this disease are classified into motor and non-motor symptoms. The motor...
- Health & MedicineOpen access
EFFICACY OF AYURVEDIC TREATMENTS IN STRESS MANAGEMENT
The significance of stress in the development of various diseases is acknowledged in both Ayurvedic knowledge and contemporary medicine. In Ayurveda, stress is known as sahasa. Due to sahasa leading to ojahksaya, or decreased immunity, the body is rendered more susceptible to var...
- Health & MedicineOpen access
IBUPROFEN-LOADED CORE-SHELL NANOPARTICLES FOR OSTEOARTHRITIS: A REVIEW
Core-shell nanoparticles present a revolutionary approach in local nanomedicine, featuring highly adjustable physicochemical structures. The advanced bimodal nanoparticles contain a specifically designed hydrophobic core for the encapsulation and molecular stabilization of the th...
- Health & MedicineOpen access
Acne vulgaris (BasooreLabniya) is a chronic inflammatory disorder of the pilosebaceous unit, commonly affecting adolescents and young adults. In the Unani system of medicine, it is associated with imbalance in temperament (Mizaj) and accumulation of morbid matter (Madda-e-Sadeedi...
- Health & MedicineOpen access
Background: Gridhrasi is a major musculoskeletal disorder categorized under the eighty Nanatmaja Vatavyadhis in Ayurveda. It closely resembles the modern clinical entity of Sciatica, typically caused by lumbar intervertebral disc herniation, canal stenosis, or nerve root compress...
- Health & MedicineOpen access
THERAPEUTIC AND TOXICOLOGICAL EFFECT OF BHALLATKA (SEMECARPUS ANACARDIUM LINN.) – A REVIEW
Bhallataka (Semicarpus Anacardum) is known vegetable irritant poison and is mentioned in Upavisha Varga in Ayurveda texts like Rasatarangini and Dhanwantari Nighantu. Semicarpus Anacardum is a member of Anacardiaceae plant family. I juice of Bhallataka (even in traces) comes in c...