Research works

MICROSPHERE-BASED DRUG DELIVERY SYSTEMS: A COMPREHENSIVE REVIEW

The targeted drug delivery is designed for endeavoring to concentrate the drug in the tissues of curiosity while reducing relative concentration of medication in the remaining tissues. There for drug is localized on the targeted site. Hence, surrounding tissues are not affected b...

CUSHING'S DISEASE IN A YOUNG ADULT WITH ADRENAL INCIDENTALOMA: A DIAGNOSTIC ODYSSEY THROUGH BIOCHEMICAL AND RADIOLOGICAL WORKUP

Cushing’s disease, resulting from ACTH-dependent hypercortisolism driven by a pituitary corticotroph adenoma, represents a diagnostically challenging endocrine disorder. We report the case of a 29-year-old male who presented with dyspnea and was found to have features of cortisol...

VITILIGO IN FOCUS: A COMPREHENSIVE REVIEW OF ETIOLOGY, DIAGNOSIS AND MANAGEMENT

In world about 0.5% -2% populations got affected by Vitiligo depigmenting cutaneous disorder. Vitiligo is characterized by loss of melanocytes like chalky white patches, non scaly macules. There are following main causes of Vitiligo first is reduced reaction to touch allergen sec...

DEVELOPMENT AND EVALUATION OF ENTERIC-COATED PANTOPRAZOLE TABLETS FOR ENHANCED GASTRIC PROTECTION

Pantoprazole is a proton pump inhibitor widely used in the management of acid-related gastrointestinal disorders, including gastroesophageal reflux disease, peptic ulcer disease, and Zollinger–Ellison syndrome. Because Pantoprazole is highly unstable in acidic conditions, an ente...

A RANDOMIZED OPEN LABELLED CONTROL CLINICAL STUDY TO EVALUATE THE EFFICACY OF MADHUKADI TAIL KARNAPOORNA AND APAMARGKSHAR TAIL KARNAPOORNA ALONG WITH GOGHRITA ORALLY IN THE MANAGEMENT OF KARNANADA (TINNITUS)

Micronutrient deficiency remains a major global health challenge, with a significant proportion of the population lacking essential nutrients such as iron, zinc, vitamin D, and vitamin B12, despite widespread use of fortified foods and synthetic supplements. Organically derived n...

ASSESSMENT OF VISUAL IMPAIRMENT IN PRIMARY SCHOOL CHILDREN AND EFFECTIVENESS OF SCHOOL VISION SCREENING PROGRAMS IN KARBALA, IRAQ

Introduction: Visual impairment in children is a significant public health challenge, particularly in low- and middle-income countries where early detection programs are often underdeveloped. Method: This study aimed to assess the prevalence and causes of visual impairment among...

ANALYTICAL METHOD DEVELOPMENT AND VALIDATION OF RP-HPLC METHOD FOR ESTIMATION OF IMEGLIMIN IN BULK AND PHARMACEUTICAL DOSAGE FORM

Imeglimin Hydrochloride is a novel anti-diabetic drug used in the management of Type 2 Diabetes Mellitus. The present study focuses on the development and validation of a simple, precise, accurate, and economical Reverse Phase High-Performance Liquid Chromatography (RP-HPLC) meth...

CLINICAL EVALUATION OF VIRECHAN KARMA, RAKTAMOKSHANA (JALAUKAVCHARANA) AND SHAMAN CHIKITSA IN SHWITRA W.S.R.VITILIGO: A CASE REPORT

Background: Vitiligo is an acquired, chronic depigmentary disorder of the skin characterized by the destruction or dysfunction of melanocytes, leading to milky-white macules and patches. In Ayurveda, it is classified as Shwitra, grouped under the broad category of Kushtha Roga. C...

A REVIEW ON ANALYTICAL METHOD DEVELOPMENT FOR DAPAGLIFLOZIN PROPANEDIOL MONOHYDRATE AND BISOPROLOL FUMARATE IN COMBINED PHARMACEUTICAL FORMULATIONS

This review analyse the analytical method associated with the co-administration of Dapagliflozin (an SGLT2 inhibitor) and Bisoprolol (a selective β1-blocker) in managing the heart failure and related metabolic comorbidities. By treating with Bisoprolol counteracts sympathetic ove...

ROLE OF NANOMATERIALS IN HEALTHCARE

Nanotechnology is revolutionising medicine by enabling highly precise diagnostics, targeted therapies, and personalised healthcare solutions. This review explores the multifaceted applications of nanotechnology across medical fields such as oncology and infectious disease control...

IMPORTANCE OF GHRITA (CLARIFIED BUTTER) IN PANDU ROGA (ANEMIA): AN AYURVEDIC AND CONTEMPORARY REVIEW

Background & Objectives: Pandu Roga is a well-described systemic disorder in Ayurvedic classics, characterized by Panduta (pallor), Daurbalya (weakness), Bhrama (giddiness), Hridspandana (palpitations), Aruchi (anorexia), and Shrama (fatigue). Its clinical presentation closely re...

REVIEW ON KAUMARABHRITYA CONCEPTS IN BHRIHATTRAYI

Kaumarbhritya is a branch of Ayurveda that deals with the care of infants and children, as well as their ailments and management. Charaka Samhita, Sushruta samhita, and Astanga Hridaya are the three bruhat trayi. The three major components of ancient Indian medicine i.e Ayurveda....

FORMULATION AND EVALUATION OF A POLYHERBAL ANTI-AGING PEEL - OFF FACE MASK

Skin aging is influenced by intrinsic and extrinsic factors, with oxidative stress playing a major role in accelerating the aging process. This study aimed to formulate and evaluate a polyherbal anti-aging peel-off face mask containing extracts of butterfly pea flower, red rice b...

A REVIEW ON ANALYTICAL METHOD DEVELOPMENT FOR DAPAGLIFLOZIN PROPANEDIOL MONOHYDRATE AND BISOPROLOL FUMARATE IN COMBINED PHARMACEUTICAL FORMULATIONS

This review analyse the analytical method associated with the co-administration of Dapagliflozin (an SGLT2 inhibitor) and Bisoprolol (a selective β1-blocker) in managing the heart failure and related metabolic comorbidities. By treating with Bisoprolol counteracts sympathetic ove...

MANAGEMENT OF OVERT HYPOTHYROIDISM WITH A SINGLE DOSE OF HOMOEOPATHIC MEDICINE PHOSPHORUS – AN EVIDENCE BASED CASE REPORT

INTRODUCTION: Hypothyroidism is a hypo-metabolic state resulting from inadequate secretion of thyroid hormones. It is the second most common endocrine disorder among women and leading cause of menstrual abnormalities in all age group. Levothyroxine is the standard lifelong mode o...

ASSESSMENT OF DIETARY PRACTICES AMONG SEVERELY BURNED PATIENTS ADMITTED TO THE INTENSIVE CARE UNIT OF THE ABIDJAN BURN CENTRE (CÔTE D'IVOIRE)

Severe burn injuries represent a major public health concern because of their high morbidity and the profound metabolic disturbances they induce. Nutritional management plays a critical role in the prognosis of severely burned patients. This study aimed to assess the dietary prac...

PREDICTIVE VALUE OF THE SYSTEMIC IMMUNE-INFLAMMATION INDEX AND RESIDUAL SYNTAX SCORE FOR MAJOR ADVERSE CARDIOVASCULAR EVENTS FOLLOWING PERCUTANEOUS CORONARY INTERVENTION AT AL-KINDY TEACHING HOSPITAL, BAGHDAD

Background: Major adverse cardiovascular events (MACE) remain an important cause of morbidity and mortality following percutaneous coronary intervention (PCI). The Systemic Immune-Inflammation Index (SII) and Residual SYNTAX Score (rSS) have emerged as promising prognostic marker...

A REVIEW FORMULATION AND EVALUATION OF CALCIUM CHANNEL BLOCKER DRUGS

Calcium channel blockers (CCBs) are among the most widely prescribed cardiovascular drugs for the management of hypertension, angina pectoris, cardiac arrhythmias, and other related disorders. Their therapeutic action is based on the inhibition of L-type calcium channels, which r...

THERAPEUTIC ASSESSMENT OF PANCHAVALKAL KWATHA ADMINISTERED VIA AVAGAHA SWEDANA IN PARIKARTIKA (FISSURE-IN-ANO): A PROSPECTIVE OPEN-LABEL TRIAL

Background and Rationale: Among anorectal ailments presenting to surgical units, fissure-in-ano occupies a clinically demanding position, constituting roughly one-tenth to one-sixth of all such referrals.[1] The condition is defined by a longitudinal mucosal breach in the distal...

ALOE VERA MUCILAGE-BASED MUCOADHESIVE BUCCAL FILMS OF TRIAMCINOLONE ACETONIDE FOR THE LOCALIZED MANAGEMENT OF RECURRENT APHTHOUS STOMATITIS: CURRENT EVIDENCE, FORMULATION STRATEGIES, AND FUTURE PERSPECTIVES

One of the most common ulcerative conditions of the oral cavity is recurrent aphthous stomatitis (RAS), which is characterized by painful, recurrent lesions that greatly impair patients' quality of life. Even though topical corticosteroids, antiseptics, and analgesics are readily...