Research works

AYURVEDIC PERSPECTIVE ON INSULIN RESISTANCE IN POLYCYSTIC OVARY SYNDROME

Background: Polycystic ovary syndrome (PCOS) is a common endocrine and metabolic disorder in women of reproductive age. Insulin resistance (IR) and compensatory hyperinsulinemia are key factors in its development, affecting 50–80% of those with the condition. These metabolic issu...

REGULAR LABORATORY MONITORING OF RENAL FUNCTION IN PATIENTS WITH CHRONIC DISEASES MAY DELAY PROGRESSION TO DIALYSIS IN JORDANIAN PATIENTS

Introduction: Regular laboratory assessment of kidney function in patients with chronic diseases plays a crucial role in the early detection of renal impairment and may help delay progression to dialysis. Methods: This multi-centre study aimed to analyse routine laboratory data o...

LARVAL EATING CAPACITY OF INDIGENOUS LARVIVOROUS FISHES AGAINST LARVAE OF CULEX QUINQUEFASCIATUS SAY IN FIELD OPERATIONAL CONDITIONS IN MONO DEPARTMENT IN SOUTH-WESTERN REPUBLIC OF BENIN, WEST AFRICA

Because of problems with insecticide resistance, alternative vector control methods are necessary. These methods include the use of biological control agents, such as larvivorous fishes. This study aimed to study larval eating capacity of indigenous larvivorous fishes against lar...

CONCEPTUAL STUDY ON EFFECTS OF AMRITA GHRITA IN GARAVISHA

In contemporary society, the consumption of Viruddhaahara (incompatible diet), fast food, food additives, and soft drinks has significantly risen. According to Ayurvedic Samhitas, these dietary habits manifest as Garavisha (artificial/concocted poison) and Viruddhaaharjanya Vyadh...

PALLIATIVE CARE AS वतरगचकतस - A DETAIL REVIEW

Dementia is a progressive neuro-degenerative disorder that significantly affects cognitive, behavioural and functional abilities in elderly individuals. In Ayurveda, no single disease entity exactly corresponds to dementia; however, the condition can be understood through the con...

LAGHUPANCHAMULA: A COMPREHENSIVE REVIEW OF ITS PHARMACOLOGICAL AND THERAPEUTIC SIGNIFICANCE

Laghupanchamula is a well-known formulation in Ayurvedic medicine, consisting of five key medicinal plants: Brihati (Solanum indicum), Kantakari (Solanum xanthocarpum), Shaliparni (Desmodium gangeticum), Prishnaparni (Uraria picta), and Gokshura (Tribulus terrestris). These herbs...

THE POSSIBLE AMELIORATIVE EFFECT OF SOME DRUGS AGAINST PARACETAMOL INDUCED ACUTE LIVER INJURY

Acetaminophen (APAP) overdose is the leading cause of drug-induced liver injury and acute liver failure all over the world. Although N-acetylcysteine is approved as the standard antidote, its therapeutic benefit is limited to early administration and moderate cases. This emphasiz...

MANAGEMENT OF REFRACTORY SACROCOCCYGEAL PILONIDAL SINUS (SHALYAJA NADI VRANA) VIA MINIMALLY INVASIVE PARA-SURGICAL ABLATION USING SNUHI-APAMARGA KSHARSUTRA: A CARE-COMPLIANT CLINICAL CASE REPORT

Background: Sacrococcygeal pilonidal sinus disease (PNS) is a chronic inflammatory disorder predominantly affecting the young adult male population. Characterized by hair penetration into the subcutaneous tissues of the natal cleft, it yields blind epithelized tracts presenting w...

INTER-RELATIONSHIPS WITH MODERN SCIENCE AND CLINICAL RELEVANCE OF SAPTA DHATU

Ayurveda, one of the oldest systems of medicine, originated in India over 5,000 years ago. It is a comprehensive system of healthcare that focuses on achieving optimal health and well-being through a holistic approach, encompassing the physical, mental, and spiritual aspects of a...

AN APPLIED STUDY OF NINE-CENTER MEDITATION FOR REDUCING MOBILE PHONE ADDICTION IN SCHOOL STUDENTS

This randomized experimental investigation examined the effects of a structured Nine-Center Meditation programme on mobile phone addiction among school students. The investigators hypothesized that consistent participation in Nine-Center Meditation would result in significant red...

DEVELOPMENT AND CHARACTERIZATION OF AMLODIPINE LOADED SELF-NANO EMULSIFYING DRUG DELIVERY SYSTEM NEEDS FOR EFFECTIVE HYPERTENSION TREATMENT

Through the development of Self-Nanoemulsifying Drug Delivery Systems (SNEDDS), the current project aims to improve the oral bioavailability and therapeutic efficacy of amlodipine, a weakly water soluble hypertension medication. Tween 20 was used as the surfactant and peppermint...

FORMULATION AND EVALUATION OF GLIPIZIDE MICROEMULSION

Glipizide is a second-generation sulfonylurea used in the treatment of Type 2 diabetes mellitus. Because of its poor aqueous solubility (BCS Class II), its oral bioavailability is limited by a slow dissolution rate. Microemulsion-based drug delivery systems are thermodynamically...

A REVIEW ON PHYTOPHARMACOLOGICAL SCREENING OF CASSIA FISTULA LINN. IN EXPERIMENTAL ANIMAL MODELS

Medicinal plants have been used for thousands of years as an important source of therapeutic agents for the prevention and treatment of various diseases. Even with the rapid advancement of synthetic pharmaceuticals, plant-derived medicines continue to play a significant role in m...

COMPREHENSIVE ANALYSIS OF THE ANTI-INFLAMMATORY POTENTIAL OF KSHARAGAD EXTRACTS: AN INVITRO STUDY

Inflammation is a protective response of the body against harmful stimuli such as infection, injury, toxins, and immune reactions. In Ayurveda, inflammatory conditions are broadly described under the concept of Shotha, which is caused by the imbalance of Doshas and other external...

FORMULATION AND EVALUATION OF MANTELUKAST SODIUM CHEWABLE TABLET

Montelukast sodium is a selective leukotriene receptor antagonist widely used for the prophylaxis and chronic management of asthma and allergic rhinitis. The present study aimed to formulate and evaluate Montelukast sodium tablets with improved tablet performance, rapid drug rele...

YUKTI TO NANO-PHARMACOLOGY: UNDERSTANDING ALPAMATRA MAHARTHATVAM AND THE THERAPEUTIC POTENTIAL OF RASAUSHADHIS

Background: Rasaushadhis represent a unique class of herbo-mineral formulations in Ayurveda, distinguished by three remarkable characteristics: administration in minute doses (Alpamatra), rapid therapeutic action (Kṣipramarogyadayitvat), and patient palatability (Arucheraprasanga...

NEW ONSET STATUS EPILEPTICUS AND MULTIFOCAL HAEMORRHAGE IN A YOUNG ADULT, A RARE CLINICAL PRESENTATION OF CNS VASCULITIS

Primary central nervous system vasculitis (PCNSV) is a rare inflammatory disorder affecting the blood vessels of the brain and spinal cord, without systemic involvement or underlying connective tissue disease. It usually presents with a wide range of nonspecific symptoms in the f...

MEDHYA RASAYANA WSR TO JATAMANSI FOR BUDDI, SMRITI & MEDHA

Jatamansi (Nardostachys jatamansi DC.) is a well-known Ayurvedic drug described for its Medhya (nootropic) and Manas-balancing properties. In the present era of increasing mental stress, anxiety disorders, and cognitive decline, there is a growing need to explore safe and effecti...

MANAGEMENT OF REFRACTORY SACROCOCCYGEAL PILONIDAL SINUS (SHALYAJA NADI VRANA) VIA MINIMALLY INVASIVE PARA-SURGICAL ABLATION USING SNUHI-APAMARGA KSHARSUTRA: A CARE-COMPLIANT CLINICAL CASE REPORT

Background: Sacrococcygeal pilonidal sinus disease (PNS) is a chronic inflammatory disorder predominantly affecting the young adult male population. Characterized by hair penetration into the subcutaneous tissues of the natal cleft, it yields blind epithelized tracts presenting w...

A RANDOMIZED OPEN LABELLED CONTROLLED CLINICAL STUDY TO EVALUATE THE EFFICACY OF AMLAKYADI GHRITA AND SHATAVARI GHRITA NASYA IN THE MANAGEMENT OF RAJONIVRITTIJANYA LAKSHANAS W.S.R. POST MENOPAUSAL SYNDROME

Background: Menopause is a physiological transition characterized by permanent cessation of menstruation due to ovarian follicular depletion and declining estrogen levels. The associated vasomotor, psychological, musculoskeletal, and urogenital symptoms substantially impair the q...