Research works

Non-blistering psoriasiform pemphigus foliaceus mimicking psoriasis: a diagnostic challenge

Abstract Purpose Pemphigus foliaceus (PF) typically presents with superficial blistering but may occasionally manifest in atypical non-blistering forms that mimic other inflammatory dermatoses. We report a diagnostically challenging case of PF presenting with widespread psoriasif...

G protein signaling capabilities at the bradykinin 2 receptor

The bradykinin 2 receptor (B2R) is one of two members of the kinin receptor family and is a G protein-coupled receptor (GPCR) that regulates important physiological processes including pain, inflammation, and cardiovascular homeostasis. Functionally, B2R is activated by the kinin...

MRI paving the way to diagnosis of acute lymphoblastic leukemia in children and adolescents – a retrospective observational study

BACKGROUND: Prompt diagnosis of childhood acute lymphoblastic leukemia (ALL) remains a clinical challenge, particularly in children presenting with normal blood counts and musculoskeletal symptoms. With the increasing use of magnetic resonance imaging (MRI) in evaluating such com...

Halophyte-derived bacterial SynComs improve soybean growth under salinity stress

Abstract Rhizosphere microbes with plant growth-promoting (PGP) traits can sustain crop productivity, yet endophyte-derived synthetic communities (SynComs) from hypersaline environments remain underexplored. We hypothesize that halophyte endophyte-derived SynComs improve stress t...

Capital market liberalization and stock price crash risk: a Shanghai-Hong Kong stock connect expansion perspective

Abstract Capital market liberalization provides foreign investors with greater access to direct investment in mainland China’s stock market. This study uses the expansion of the Shanghai–Hong Kong Stock Connect as a quasi-natural experiment. The sample consists of A-share listed...

Correlation between high-risk Human Papillomavirus (HPV) viral load and cervical lesions across different subtypes, along with the development of a clinical prediction model

Abstract Objective The study aims to investigate the correlation between the viral loads of HPV16/18 and 16 other high-risk HPV types (designated as non-16/18 group) and the severity of cervical lesions, and to develop a HSIL+ risk prediction model to furnish evidence for pragmat...

Reproducibility and validity of dietary polyphenols derived from 24-hour dietary recalls in the Anhui Lifestyle Validation Study

Abstract While 24-hour dietary recalls (24HDRs) are increasingly used to assess polyphenol-disease associations, their performance for measuring total dietary polyphenols and their subclasses remains unknown. In the Anhui Lifestyle Validation Study, 432 community-dwelling adults...

ObviousBench: The Cost of Not Making Obvious Mistakes

Language models deployed in public-facing products still make mistakes any careful person would catch instantly: miscounting the letters in a word, botching a trivial spelling transform, ignoring a plainly stated constraint. These visible failures erode user trust faster than fai...

Mamdani’s Mending Story: Rescaling Democratic Peoplehood in an Age of Interregnum

Abstract Zohran Mamdani’s mayoral win in New York City has sparked debates about the replicability of democratic socialism. This article instead compares how Mamdani’s deployment of stories of peoplehood diverges from the strategies used by ideological peers like Alexandria Ocasi...

Ultrasonography-Guided Long Peripheral Catheters: Real-World Outcomes in Hospitalized Children

OBJECTIVE: Despite being the most common vascular access devices in pediatric settings, short peripheral catheters (SPCs) frequently result in difficult insertion, limited dwell time, and multiple replacements. Ultrasonography-guided long peripheral catheters (LPCs) may improve c...

Teachers’ Factors Contribute Meaningful Variance in Association with Autistic Adolescent Sexual Behavior Beyond Parental Factors

Abstract Introduction: Although substantial progress has been made in understanding sexual communication between autistic adolescents and parents or teachers separately, relatively little research has examined these influences together across the two main developmental contexts i...

Benchmark evaluation of OpenAI-o1 vs DeepSeek-R1 for junior anesthesiologists in Chinese hospitals: hazards of fast large language models use in high-stakes specialties

Abstract Purpose Junior physicians may experience critical competency gaps during the transition to unsupervised practice, particularly in high-risk specialties such as anesthesiology, where errors can compromise patient safety. Although large language models (LLMs) are being rap...

Bacteriophage inactivation to prevent carry-over in preclinical assays with mycobacteria

Abstract Background Bacteriophage carry-over, the continued lytic activity of residual phages after experimental sampling, poses a significant challenge in bacteriophage research, potentially skewing experimental results, particularly in the context of preclinical studies where p...

Comparative study of different europium doping techniques on the structural and optical properties of ZnO nanoparticles

Abstract Zinc oxide nanoparticles (ZnO NPs) were synthesized via a co-precipitation method and doped with Eu 3+ ions using three different approaches: in-situ doping during synthesis (Eu:ZnO(P)), post-synthesis doping (Eu:ZnO(S)), and modification of commercially available ZnO (E...

In silico pipeline for 2-SCN-NQ: molecular docking, molecular dynamics and quantum chemistry against trypanosomatid trypanothione reductase

Reproducible in silico workflow (AutoDock Vina docking, OpenMM molecular dynamics in triplicate, GFN2-xTB/DFT) supporting the mechanistic study of 2-SCN-NQ against Trypanosoma cruzi and Leishmania amazonensis.

The microbiological spectrum and clinical course of adolescents and adults with peritonsillar abscesses

A peritonsillar abscess (PTA) displays a purulent infection arising from acute tonsillitis, involving a variety of aerobic and anaerobic bacteria. Fusobacterium necrophorum, a gram-negative anaerobe, is considered a significant risk factor for complications like Lemierre's syndro...

Prevalence, bacterial etiology, and risk factors of clinical and subclinical mastitis in dromedary camels (Camelus dromedarius) across pastoral and peri-urban production systems in south-central Somalia

Abstract Mastitis is a major constraint to camel milk productivity, udder health, and milk safety in pastoral and emerging peri-urban dairy systems, yet comparative epidemiological data across these systems remain scarce. This cross-sectional study investigated mastitis in lactat...

Using a digital health tool to strengthen community engagement in arboviral disease prevention: an implementation study in Colombia

Abstract Background Arboviral diseases remain major public health problems in Colombia. Mobile applications such as WhatsApp are increasingly being used to support health interventions by improving community engagement and preventive practices. Given its widespread use in Colombi...

The Geometry of the Regime Space: How the Strategic-Inattention Boundary Bifurcates at a Cusp

The many models of this programme are one payoff, and the boundary that sorts them into strategic-inattention and active regimes is not a single surface: past a cusp in the production response it bifurcates into a hysteretic band, and it is inside that band—on the productive subs...

Performance evaluation of an axial-flow gas turbine compressor using methanol droplets as the cooling medium

This study employs ANSYS CFX to analyze wet compression technology in the NASA Stage 35 axial compressor. A primary challenge of wet compression is the risk of blade erosion caused by slow-evaporating or poorly atomized droplets. To mitigate this, methanol was selected as the eva...