Research works

A novel optimization of API release using hybrid models

Abstract Polysaccharide-based drug delivery systems have to be closely watched in terms of drug release in the body over time if they want to be able to achieve maximum therapeutic effectiveness and maintain controlled bioavailability. The work presents a data-driven framework th...

Pathological fracture of the right femur secondary to high-flow intraosseous arteriovenous malformation complicated by traumatic pseudoaneurysm: staged endovascular embolization and conservative orthopedic management—a case report

Abstract Background Primary intraosseous arteriovenous malformations (AVMs) are exceedingly rare vascular anomalies that can weaken bone architecture and predispose to pathological fracture. Their imaging appearance frequently mimics malignant bone tumors, creating significant di...

Ears for examinations: a multicentre quasi-experimental evaluation of AI-generated revision podcasts on learning outcomes and retention among medical students

Abstract Background Medical curricula overload necessitates efficient, self-directed learning strategies that can utilize ‘dead time’ for study. AI-generated audio offers a scalable resource for this purpose, yet evidence regarding its efficacy in low-resource settings is limited...

From intravascular imaging to adaptive vascular care: intelligent photonics and digital twins in panvascular disease

Panvascular diseases (PVDs) stand as the leading cause of global mortality, necessitating a paradigm shift from local anatomical repair to the systemic restoration of vascular homeostasis. While intravascular optical imaging has revolutionized diagnosis, it remains a passive obse...

Landauer-Compensated Information Erasure in Cyclic Cosmology

A thermodynamically consistent mechanism for cross-cycle information transfer is proposed, combining holographic boundary encoding, de Sitter horizon thermodynamics, and a Cyclic Cascading Dark Energy (CCDE) model in which the Hubble parameter $H(t)$ tends asymptotically to zero,...

Investigating dynamic premium in Indian green stocks amid evolving Fama and French factors in tandem with dynamic liquidity considerations

Abstract Purpose This study attempts to determine whether Indian green stocks offer superior returns relative to the market expectations and to examine variations in Fama–French factors, liquidity factors, Jensen’s alpha, and the Sharpe ratio of green stocks. It also assesses the...

Priorities for breast cancer risk assessment in UK women under age 50: a survey and discrete choice experiment

BACKGROUND: National guidelines recommend English women between 30 and 49 years with moderate/high risk of breast cancer (BC) be offered screening and prevention interventions. Identification largely relies on family history-based criteria amongst women self-presenting in primary...

A numerical study comparing hydrodynamic performance of circular and square cross-sectional wetted venturi scrubbers

Abstract The contaminants are cleared from the gas before they are released into the environment by venturi scrubbers that are easy to use and effective gas cleaning equipment. Venturi scrubbers use liquids to remove contaminants from the gaseous medium. In the present study, sin...

Fake It If You Can’t Make It: Nella Larsen and the Ideal of Autonomy

Abstract This article argues for Nella Larsen’s theory of art by reading her two major novels, Quicksand (1928) and Passing (1929), in the light cast back by her last publication, the plagiarized story “Sanctuary” (1930). In this reading, “Sanctuary” is a perverse tribute to the...

Depressive symptoms in amyotrophic lateral sclerosis: associations with quality of life, disease progression and perceived social support—a German multicenter study

BACKGROUND: Amyotrophic Lateral Sclerosis (ALS) is a rapidly progressive, fatal neurodegenerative disease. Patients with ALS are at increased risk of developing depressive symptoms. A clearer understanding of the associations between depressive symptoms, disease progression, heal...

Differential Accuracy and Concordance of ChatGPT and DeepSeek for Image-Based Questions in Undergraduate Medical Education

Abstract Large language models (LLMs) such as ChatGPT (GPT) and DeepSeek (DS) are increasingly explored in medical education and practice. This study compared the accuracy and concordance of GPT and DS in answering multiple-choice Progress Test questions (2013–2024) across three...

The Universe as a Projection: Additional Consequences in Light of the Grand Unified Theory (GUT)

In previous works, the author proposed a holographic projection model, a Generalized Holographic Principle, a Grand Unified Theory (GUT), and a "Seven Forms of Matter" (7FM) model. This article demonstrates that the integration of these approaches creates a closed ontological sys...

Secure and reliable SWIPT in active RIS-aided downlink NOMA with hardware impairments

Abstract Due to growing system complexity and the vulnerability of wireless transmissions to information leakage, maintaining secure and private communication in sixth-generation (6G) networks continues to be a significant problem. By enabling wireless power transfer to distant I...

At dawn we did not sleep. Contribution to the dawn of functional group translocation: ortho → para 1,3-acyl migration of 2-fluoroacetophenone

Abstract Functional Group Translocation (FGT) was defined ( Chem. Soc. Rev. 2026) as a transformation in which the molecular formula, the identity of the functional group, and the carbon framework remain unchanged, while only the bonding position of the functional group is altere...

Sublattice engineering and crystal system design: microscopic pathways to enhanced performance in halide solid-state electrolytes

Abstract Halide solid-state electrolytes (HSSEs) hold great promise for all-solid-state batteries, but their ionic conductivity and electrochemical stability still remain key challenges in practical applications. This review systematically links the evolutionary trajectory of HSS...

Whole genome comparative analysis shows limited Escherichia coli co-occurrence within co-habiting humans and dogs

Abstract Background Dogs are one of the most popular companion animals in the UK, with an estimated 13.5 million within UK households. Within these households, human-animal physical interactions may lead to inter-species bacterial sharing, including Escherichia coli . E. coli is...

Defect-mediated generation–recombination dynamics governing conductance response in floating-body transistors

As CMOS technologies evolve toward ultra-thin floating-body architectures, defect-mediated carrier dynamics increasingly dominate device behavior, challenging conventional linear interpretations of electrical response in nanoscale transistors. In this work, we demonstrate that th...

Pulsed Field Versus Cryoballoon Ablation for Atrial Fibrillation: A Systematic Review and Meta-Analysis

In the treatment of atrial fibrillation (AF), cryoballoon ablation (CBA) is associated with a high incidence of pulmonary vein reconnection, potentially limiting long-term efficacy. Pulsed field ablation (PFA) has emerged as a promising alternative with the potential for improved...

Childhood obesity governance in Qatar: a policy and legal benchmarking analysis against international child rights and WHO frameworks

Abstract Background Childhood obesity prevention requires coherent national policy packages that address children’s food, physical activity, school, health service, and governance environments. Yet country-level policy claims are often made without auditable verification against...

A non-invasive simplified scoring system to predict airway mucus plugs in asthma

Abstract Background Airway mucus plugs are a core pathological feature of severe asthma and are closely associated with airflow limitation and poor prognosis. However, rapid and efficient clinical screening tools for identifying airway mucus plugs in asthma are currently lacking....