Research works

Beyond the locus coeruleus: pupil dynamics as a systems-level marker of neuromodulatory influences on hippocampal memory

Dopamine and norepinephrine regulate hippocampal plasticity through molecular, cellular and circuit mechanisms that shape which experiences are encoded and later remembered. Translating these mechanisms into human memory research remains challenging because direct measures of end...

Young adults’ experiences of using FREED-Mobile, a smartphone friendly intervention designed to facilitate help-seeking for eating disorders

Abstract Background Early intervention increases the likelihood of eating disorder recovery, yet many young people delay seeking professional support for eating difficulties. We developed a smartphone-friendly, online intervention - FREED-Mobile [FREED-M] to encourage early help-...

The energetics of high temperature oxidation and formation mechanisms in binary lanthanide nitrides (LnN)

Abstract Nitride-based materials present exceptional thermal and structural properties for advanced material applications, however accurate determination of their thermodynamic properties is critical to their deployment. Herein, the standard enthalpies of formation, Δ H f ° , for...

One foot after the other – embodied information on the West Highland Way

Purpose Embodied information is posited to be a rich and novel concept with which to explore information behaviour in serious leisure pursuits (Cox et al., 2017). This research uncovers how embodied information is experienced on the West Highland Way (WHW), a long-distance hiking...

A multiomic atlas reveals distinct immune landscapes in preterm and term chronic placental inflammation

Chronic placental inflammation (CPI), an umbrella term encompassing chronic chorioamnionitis, chronic villitis, and chronic deciduitis, is associated with preterm birth (PTB), yet its cellular and molecular determinants across gestation remain poorly defined. Here, we constructed...

Engineered 3D Fibronectin‐Based Environments Modulate the Pathogenic Profile of Arthritic Synovial Fibroblasts

Inflammation is essential for fighting infections and initiating tissue repair, but chronic unresolved inflammation underlies many conditions, like cancer and autoimmune disorders. While dysregulated immune responses drive chronic inflammation, non‐immune stromal cells such as fi...

The Impact of Heterogeneity in Individual Characteristics and Motivation to Quit Heroin Use on Contingency Management and Opioid Agonist Treatment Response: A Latent Class Analysis

ABSTRACT Introduction Contingency Management (CM) involves the systematic application of positive reinforcement (financial incentives) to promote behaviour change, to improve treatment outcomes for individuals with opioid use disorder (OUD). To better understand patient heterogen...

Rod photoreceptors have a dual dependency on both aerobic glycolysis and OXPHOS and diverge metabolically from other retinal neurons

The retina metabolizes glucose into lactate, a hallmark of aerobic glycolysis known as the Warburg effect. Although evidence points to rod photoreceptors as the primary source of aerobic glycolysis, a comparison of the energy metabolism in different retinal neurons has yet to be...

Epistemic violence and academic repression: Anti-Palestinian racism and the politics of knowledge production in the context of the Gaza genocide

This paper critically interrogates the institutionalized repression of pro-Palestinian scholarship in academia, particularly within psychology and allied social sciences, framing it within broader neoliberal and settler-colonial structures. Drawing on postcolonial and decolonial...

NoiBic: a noise-tolerant biclustering algorithm for high-throughput gene expression data analysis

Abstract Motivation High-throughput transcriptomic technologies generate large-scale gene expression datasets for functional module discovery. However, technical and biological noise can obscure coherent expression patterns and compromise module detection. Noise-tolerant methods...

AVERAGE TREATMENT EFFECT LOCALIZATION: PROJECTION METHODS IN SYNTHETIC CONTROL

Many real-world policies and business interventions require assessing short-term effects to inform timely decisions, even though most causal inference methods focus on long-term average treatment effects. In this article, we introduce average treatment effect localization (ATEL),...

Interface-controlled phase stability in polymorphic HfO2 revealed by machine-learning atomistic simulations

HfO 2 exhibits rich polymorphism, and competition among different phases underpins many of its functional properties. Yet bulk free-energy relations alone cannot explain phase selection at mixed-phase boundaries, where interface orientation and structural continuity constrain col...

Dynamics of human cardiogenesis and its disruption in trisomy 21

Abstract Developmental dynamics involve the specification of diverse cell types and their spatial organization into multicellular niches 1 . Here we combine single-cell and spatial multiomics to define 21 distinct tissue niches in the developing heart, which we use to develop a c...

HelexKids 2.0: A linguistically annotated lexical database building on HelexKids

Abstract HelexKids 2.0 represents an annotated expansion of the original HelexKids, a word frequency database compiled from Greek and Cypriot elementary school textbooks. This article presents the extended annotation methodology employed to enrich the database with part-of-speech...

Third place visiting among mid-to-older adults: a cross-classified multilevel analysis

Background Visiting ‘third places’ outside of the home or workplace is associated with better health. For mid-to-older adults, visiting third places provides opportunities for social connectedness and physical activity that can support healthy ageing. We aimed to identify factors...

ARNAI: Artifact Removal Network Based on Autoencoding and Inpainting for Robust Spinal Image Segmentation and Measurement

Purpose To develop an artificial intelligence framework, robust to spinal implants, for automated measurement of spinopelvic parameters on postoperative radiographs. Materials and Methods Lateral lumbar spine radiographs from two institutions (internal dataset [ n = 2486]: Januar...

Assessing the impact of layer selection on CAM-based explainability for YOLOv8: a study on hand-sketched digital logic circuits

Abstract Class activation mapping (CAM) techniques improve the interpretability of deep neural networks by highlighting image regions that contribute to model predictions. However, the quality of CAM explanations can vary considerably according to the selected target layer. This...

Traffic congestion control for ARZ model with an arbitrarily large input delay

This paper addresses the stabilisation problem for Aw-Rascle-Zhang (ARZ) traffic model in the presence of an arbitrarily large input delay. The linearised ARZ model is a 2×2 hyperbolic partial differential equation (PDE) system with proximal reflection, which introduces significa...

Linear morphometrics fail to support strong sexual dimorphism in Uintatherium anceps

Uintatheres, mammals belonging to the extinct order Dinocerata, are among the most recognizable of all Paleogene (~66–23 Ma) organisms. Unmistakable for their bizarre skulls with multiple pairs of horns and saber-like upper canines, uintatheres have captivated paleontologists sin...

A ribosomal pseudouridine drives an oncogenic translation program

Dynamic ribosome heterogeneity has emerged as a potential layer of translational regulation, but whether variation in ribosomal RNA (rRNA) modification stoichiometry can selectively control the translation of mRNAs with shared encoded features remains unclear. Here we show that S...