Research works
The research papers we track — the newest first. Works with a plain-language summary link to it.
134751 work(s)
- Health & MedicineOpen access
PurposeHepatocellular carcinoma (HCC) refractory to locoregional therapies remains a major clinical challenge.This study evaluated the efficacy and safety of locoregional high-dose autologous natural killer (NK) cell therapy combined with hepatic arterial infusion chemotherapy (H...
- Materials & EnergyOpen access
Urea is a vital nitrogen fertilizer for global food security; however, its production remains carbon-intensive owing to heavy reliance on fossil fuel–based H 2 . To reduce the carbon emissions of the urea production process, capturing CO 2 from the flue gas has emerged as a promi...
- Health & MedicineOpen access
The continuous emergence of SARS-CoV-2 variants has enabled partial escape from neutralizing antibodies, necessitating frequent updates of vaccine antigens. These observations motivate vaccine strategies that can redirect antibody responses toward conserved regions of the spike (...
- Health & MedicineOpen access
To evaluate the diagnostic performance of machine learning (ML) algorithms based on radiomic features extracted from orthopantomographic (OPG) images in differentiating cervical caries from cervical burnout. A total of 170 OPG images were retrospectively analyzed, including 85 ce...
- Climate & EnvironmentOpen access
Climate informed pediatric care – Nurturing a better future for children
Introduction Climate change poses significant health risks and children are particularly vulnerable to its effects. In 2024, the American Academy of Pediatrics (AAP) updated its clinical recommendations for climate-informed care in a policy statement, urging pediatricians to inco...
- AI & ComputingOpen access
Gondauri’s earlier Zenodo preprint [1] reported a deterministic approximation guarantee of \(1/3 - 7.5 \times 10^{-45}\), strictly below one third. Li and Li [2] acknowledge that correspondence concerning this preprint motivated their independently developed construction, which a...
- Health & MedicineOpen access
Breast cancer presents a significant therapeutic challenge due to the substantial molecular and genetic diversity among its subtypes, thereby necessitating the development of refined intervention strategies. Macromolecular therapies, such as monoclonal antibodies, are often hinde...
- Society & EconomicsOpen access
Macroeconomic determinants of environmental degradation in Africa: A STIRPAT model analysis
Environmental pressure in Africa is shaped by economic expansion, demographic scale and the energy required to sustain production, yet these relationships are difficult to identify when countries are exposed to common shocks and respond heterogeneously. This study revisits the ma...
- Health & MedicineOpen access
Metabolic dysfunction-associated steatotic liver disease (MASLD) develops over time, yet most hepatokine studies are cross-sectional.We investigated the temporal regulation of the activin-follistatin axis and growth differentiation factor 15 (GDF15) in high-fat diet (HFD)-induced...
- Health & MedicineOpen access
Homocysteine and its vitamin cofactors are associated with vascular biology, but post-stroke measurements are vulnerable to confounding and reverse causation. This study compared serum homocysteine, vitamin B6, vitamin B12 and folate between adults with acute ischemic stroke and...
- BiologyOpen access
Revolutionizing drought defense: The water-plant-microbe synergy in climate-smart agriculture
Global warming-induced water scarcity threatens agricultural sustainability. While precision irrigation and microbial inoculants are recognized as effective individual strategies, their synergistic potential remains under-explored. This review synthesizes recent advances in the "...
- BiologyOpen access
Background Surgical site infection (SSI) is the most common postoperative complication and leads to a poor prognosis. SSI triggers the acute-phase response, which leads to increased levels of high-sensitivity C-reactive protein (hsCRP) and myeloperoxidase (MPO). The HDL-associate...
- Health & MedicineOpen access
Biological reconstruction with recycled autografts is an established option for limb salvage after bone tumor resection, but complications such as graft failure and nonunion remain concerns. Pedicle freezing was introduced in 2010 and showed potential in reducing nonunion. Howeve...
- BiologyOpen access
Population growth and urbanization have increased wastewater generation, producing large volumes of sewage sludge requiring sustainable management. Anaerobic digestion and composting produce liquid centrate (LC) and composted sewage sludge (CSS), which can reduce dependence on sy...
- Society & EconomicsOpen access
Designing the waiting experience: How order tracking shapes consumer engagement and loyalty
The post-purchase waiting period is an important yet underexamined stage of the digital customer journey. Consumers increasingly interact with order tracking systems during this phase, yet research has treated tracking primarily as a logistics tool rather than an experiential tou...
- BiologyOpen access
The endolysosomal system is central to neuronal homeostasis, yet how nutrient sensing regulates endolysosomal lipids remains poorly understood. Bis(monoacylglycero)phosphate (BMP), a signature phospholipid of late endosomes, is required for intraluminal vesicle formation, cholest...
- Climate & EnvironmentOpen access
Short-lived radiogenic isotope systems provide unique constraints on the preservation of early-formed reservoirs in Earth's mantle. We present the largest high-precision μ 142 Nd dataset for a single hotspot, comprising 55 analyses of 29 shield-stage tholeiitic basalts from the H...
- Health & MedicineOpen access
Emerging role of cGAS-STING in the pathogenesis of allergic diseases
The cyclic GMP-AMP synthase-stimulator of interferon genes (cGAS-STING) signaling pathway, classically recognized as a crucial cytosolic DNA-sensing mechanism in innate antiviral immunity, is now emerging as a pivotal regulator of sterile inflammation and immune dysregulation. Re...
- Materials & EnergyOpen access
Microbiologically influenced corrosion (MIC) threatens the safety and durability of drinking water distribution systems (DWDS), while the effects of fluctuating redox conditions on microbial corrosion evolution remain unclear. In this study, an alternating anoxic–aerobic system w...
- Engineering & TechnologyOpen access
Experimental investigation and predictive modeling of wear in Al7075–SiC nanocomposites
This study examines the dry sliding wear behavior of Al7075-3 wt% SiC nanocomposites using a pin-on-disc tribometer and ASTM G99 standards. Experimental results indicate that tribological responses are strongly affected by sliding distance, applied load, and sliding speed. When t...