Research works

Use of Digital Assistants as Assistive Technology for Students With Extensive Support Needs or Intellectual Disabilities

Sophia is a high school student with an intellectual disability and moderate expressive language delays. She uses a picture schedule, a single switch yes/no device, and a tablet (Apple iPad) with an augmentative and alternative communication (AAC) app as her primary AAC system. R...

Digital twin for city traffic emissions using deep vision and real time monitoring

Urban on-road air pollution remains a pervasive threat to public health, yet its management is fundamentally constrained by a lack of spatiotemporal precision in emission inventories. Conventional inventories rely on static, registration-based proxies that fail to capture the hig...

Clinical and genetic risk factors for anthracycline‑induced cardiotoxicity in Chinese early‑stage breast cancer patients: a candidate gene study

PURPOSE: This study aimed to clarify the incidence of anthracycline-induced cardiotoxicity (ACT) and identify its clinical and candidate genetic risk factors in Chinese early-stage breast cancer patients, so as to provide evidence for clinical risk assessment and individualized c...

Infrared spectroscopy of H3+ and Hn+ ions in helium nanodroplets

This work reports the infrared laser spectroscopic study of the H3+ and Hn+ (n = 5, 6, 7, 9) ions in helium droplets. The ions were produced upon electron impact ionization of helium droplets and charge transfer to small hydrogen clusters formed within the He droplets. The spectr...

EU excess capacity management through member states-driven patient mobility: economic and legal aspects

Capacity management plays an increasingly important role in healthcare delivery, both at national and supranational level, in increasing value for money. In this paper, we propose using cross-border patient mobility across European Union (EU) countries to pool demand and reduce e...

Integrated assessment of microplastic contamination in bank sediments of urban Rivers in Khulna, Bangladesh

Microplastic pollution has emerged as a growing environmental concern in freshwater ecosystems, particularly in rapidly urbanizing regions of developing countries. This study provides the first integrated assessment of microplastic contamination in the bank sediments of the Bhair...

Materials and Music: Selective Imperfection as a Generative Framework for Analysis, Creativity and Discovery

ABSTRACT We introduce materiomusic as a generative framework linking the hierarchical structures of matter with the compositional logic of music. Across proteins, spider webs, and fluid or flame dynamics, vibrational and architectural principles recur as tonal hierarchies, harmon...

Public perception of urban agricultural heritage systems: based on VR eye-tracking

Urbanization severely threatens the dynamic conservation of Agricultural Heritage Systems (AHS). Focusing on the Haizhu High Bed-Low Ditch Agroecosystem (HHBLDA) in Guangzhou, China—a rare urban AHS facing rapid encroachment—this study integrates the Semantic Differential (SD) me...

A large-scale in silico chimera-based strategy for engineering low-immunogenic L-asparaginase from Penicillium cerradense

L-asparaginase (L-ASNase) is an amidohydrolase with high therapeutic value for the treatment of acute lymphoblastic leukemia (ALL). However, its clinical application is limited by immunogenicity, allergenicity, and adverse effects from glutaminase activity. In this study, we engi...

Imperfect detection and sampling effort shape ground beetle (Carabidae) diversity indicators in large-scale monitoring

Soil biodiversity indicators are increasingly used to inform environmental assessment and policy, yet their robustness is often constrained by heterogeneous sampling designs and imperfect species detection. Surface-active arthropods, such as ground beetles (Carabidae), are widely...

Microbial self-healing of cracks in 3D-printed cementitious materials: Use of recycled sand and bentonite as bio-carriers

A bacterial self-healing system for 3D printing of mortars to mitigate shrinkage cracking and improve the durability of printed elements is presented. In this study, the impacts of incorporating Bacillus subtilis (BS) cultures and calcium lactate (CL), optimizing their concentrat...

Multi-scale experimental and numerical analysis of thermal conductivity improvements in metal hydride composite systems

The inherently low thermal conductivity of metal hydrides significantly hinders heat transfer and, consequently, the kinetics of hydrogen absorption and desorption processes. To address this limitation, strategies such as adding high-thermal-conductivity materials have been explo...

Evaluating the influence of particle swarm optimization parameters on hybrid convolutional neural network–multilayer perceptron models for short-term load forecasting

Accurate short-term load forecasting (STLF) is crucial for reliable and efficient power system operation. This study investigates how Particle Swarm Optimization (PSO) parameter configurations affect the optimization behavior and forecasting accuracy of a hybrid Convolutional Neu...

Transcranial alternating current stimulation as treatment for delirium: A multicenter randomized double-blind sham-controlled pilot study on safety and feasibility

Delirium is an acute neuropsychiatric syndrome with currently no effective treatment. The acute encephalopathy underlying delirium is characterized by diffuse oscillatory slowing on electroencephalography (EEG). Based on its capacity to modulate oscillatory activity, 10 Hz transc...

A multimedia encryption scheme based on a lightweight predator-prey simulation and chaotic dynamics

Current encryption systems face increasing challenges from ever more sophisticated attacks, motivating the exploration of alternative schemes that offer stronger security and higher performance. In this work, we propose a dynamic multimedia encryption system based on a lightweigh...

Association of out of pocket healthcare expenditure with household consumption among marginal people and women entrepreneurs in Bangladesh during the COVID 19 pandemic

The crowding-out effect of Out-of-Pocket (OOP) healthcare expenditure is crucial in microcredit recipient households as it diverts essential funds for critical expenditures such as food, education, clothing and footwear, and transportation. Eventually, it hampers the intended imp...

Effects of vineyard inter-row grass cover treatment on microbial diversity and metabolite profiles during Cabernet Sauvignon fermentation

Inter-row grass cover is an ecological management strategy that profoundly affects vineyard microecology, yet its effects on fermentation-associated microbial diversity and wine metabolites remain incompletely elucidated. This study compared the effects of inter-row clean tillage...

Benzothiazole derivatives target oligoadenylate synthetase and enhance RSV vaccine efficacy as adjuvants

2′,5’ oligoadenylate (2-5A) activates RNase L to degrade intracellular RNA and inhibit viral proliferation. The resulting nucleotide fragments bind RIG-I-like receptors to initiate type I interferon (IFN-I) signaling, enhancing maturation of antigen processing cells to trigger ad...

Temporal associations between severe infection and long-term risk of incident arrhythmias: a population-based cohort study

The long-term impact of severe infection on arrhythmia risk across the cardiac rhythm spectrum remains incompletely characterized. We investigated the association between hospital-treated infection and incident arrhythmias, examining temporal patterns, pathogen and site specifici...

Synthesis and computational evaluation of novel indazole-based benzamide derivatives as anti-tubercular agents via DFT, molecular docking studies

A series of indazole-based benzamide derivatives (6a–6p) were synthesized via amide cross-coupling reactions and characterized using FTIR, NMR, and HRMS techniques. Density functional theory (DFT) and time-dependent DFT (TD-DFT) studies were performed to investigate the electroni...