Research works

Assessing the interactive effects of land use and climate change on species assemblages of giant panda and its sympatric large- and medium-sized terrestrial mammals

Land use and climate change are currently two most important drivers of biodiversity loss worldwide. Although the effect of these two drivers on species assemblages has been widely assessed both in isolation and in combination, their interactive effects (i.e., additive, synergist...

All Seven Clay Millennium Problems Sealed via Universal σ-Involution

Formal computational sealing of all 7 Clay Millennium Prize problems through universal σ-involution structure. SEALED PROBLEMS:✓ Riemann Hypothesis — functional-equation involution σ(s ↔ 1−s)✓ Hodge Conjecture — Poincaré duality involution σ(H^{k,k} ↔ cycles)✓ P vs NP — search-re...

Agricultural interventions in developing-region smallholder systems: A harmonized outcome–metric meta-analysis of productivity, livelihood, and welfare outcomes

Agricultural interventions are central to smallholder productivity, livelihoods, and food-security policy in developing regions, but their evidence base is fragmented across outcomes, effect metrics, designs, and contexts. This study provides a quality-controlled, harmonized outc...

Validation of the Multidimensional Scale of Perceived Social Support (MSPSS) in Diné bizaad (Navajo): randomized comparison of a community translation versus a forward translation

The Multidimensional Scale of Perceived Social Support (MSPSS) is a 12-item psychometric instrument that assesses perceived social support (PSS) with a well-established three-factor structure: family, friends, and significant others. Having a way to measure PSS is important becau...

Influence of total occlusal convergence and auxiliary retentive features on regional marginal discrepancy in milled and 3D-printed short provisional crowns—an in-vitro study

This in-vitro study evaluated the influence of total occlusal convergence (TOC) (10°/20°) and auxiliary retentive features (ARF) (groove, proximal box) on regional marginal discrepancy in milled (CopraTemp PMMA) and 3D-printed (Asiga Dentatooth) short (3 mm) provisional crowns (P...

Integrative Genomic Analysis Reveals Molecular and Clinical Disparities between Bladder and Upper Tract Urothelial Carcinoma in K-MASTER Program

Purpose: The clinical outcome of urothelial carcinoma presents significant variability, reflecting its molecular composition, epidemiologic attributes, and primary site of origin. Despite histological similarities, upper tract urothelial carcinoma (UTUC) and bladder urothelial ca...

Targeting PRMT5 to reshape the immune microenvironment and reverse Trop2 ADC resistance in triple-negative breast cancer

Triple-negative breast cancer (TNBC) patients often develop resistance to Trop2 antibody-drug conjugate (ADC), and plasmacytoid dendritic cell (pDC) dysfunction is associated with poor prognosis in TNBC, but the underlying mechanism linking these two phenomena remains unclear. Th...

Monitoring of oxidative stress and acute phase proteins following testes exposure with ultrasound waves in cats

Ultrasonic therapy has harmfully effects on the structure and function of the testis. Various mechanisms are involved in the impact of ultrasound waves on testes tissue. This study aimed to investigate the effects of ultrasound exposure on cat`s testes by monitoring acute phase p...

The digital divide in intimate relationships: Heterogeneous effects of internet use on marital stability

The impact of Internet use on marital stability remains debated. Prevailing narratives often portray the Internet as a “marriage disruptor”, overlooking critical heterogeneity among users. This study tests whether structural resource advantages—the cognitive, institutional, and c...

Improving reanalysis hub-height wind speeds and wind shear across large spatial domains using near-surface observational networks

Data-driven approaches have emerged as a complementary strategy to physics-based models for learning unresolved processes and parameterization biases in reanalysis products. Most data-driven efforts have focused on improving reanalysis wind speeds at heights where observational d...

Recognizing the exceptional, ignoring the everyday: a qualitative study of work recognition among paramedics

The paramedic profession is undergoing a significant transformation driven by sociodemographic changes and evolving healthcare needs. As the profession shifts away from its historically transport-focused role toward more complex clinical, psychosocial and non-urgent transport, li...

Progress towards Onchocerciasis elimination in Senegal’s historical transmission zones, following sustained annual mass drug administration and multilevel surveillance

Onchocerciasis remains a major public health problem in sub-Saharan Africa, despite decades of control efforts. In Senegal, transmission was historically focal but intense along the Gambia and Falémé river basins in the southeast of the country. Building on the legacy of the Onch...

Occurrence, antimicrobial susceptibility and genetic diversity of Devriesea agamarum strains isolated from captive lizard collections

Devriesea agamarum is a recognized pathogen of some reptile species. However, our knowledge on epidemiology as well as phenotypic and genotypic properties of this microorganism is still not fully elucidated. Therefore, the aim of the present work was to assess the occurrence of D...

Unraveling the CDPK gene superfamily in Dalbergia species by comparative genomics and drought stress responsiveness

Calcium dependent protein kinases (CDPKs) are very important calcium-sensing protein kinases which decode intracellular calcium signals and transduce them into phosphorylation-mediated signaling events that allows plants to survive under environment stresses. While the function o...

Association between platelet-to-white blood cell ratio trajectories and all-cause mortality in critically ill patients with acute exacerbation of chronic obstructive pulmonary disease: a retrospective cohort study

AECOPD is a leading cause of ICU admission and death in patients with COPD, yet readily accessible biomarkers for dynamic risk stratification remain scarce. The platelet-to-white blood cell ratio (PWR) is a promising inflammatory marker reflecting inflammatory burden and regenera...

The diagnosis to surgery interval and overall survival in patients with cervical cancer

Importance Evidence regarding the association of the diagnosis to treatment interval (DTI) and survival can inform clinical care and health policy. Data in this regard are currently lacking for cervical cancer. Objective To examine the relationship between the DTI and overall sur...

Nurse leaders’ perceptions of integrating the nurse practitioner role in Finland’s wellbeing services counties: A qualitative study

Background In Finland, Nurse Practitioner (NP) role integration remains fragmented amid ongoing health and social care reform. Leadership is a key determinant of role development, yet evidence on how nurse leaders advance NP role integration remains limited. Purpose To examine nu...

Efficient removal of regorafenib from aqueous solutions using KOH-activated hazelnut husk-derived activated carbon: adsorption mechanism, kinetics, isotherms and thermodynamics

In this study, activated carbon was produced from hazelnut husks, an agricultural biomass waste, by chemical activation and thermal carbonization, and the performance of the resulting adsorbent in removing Regorafenib from aqueous solutions was investigated. The textural properti...

Preoperative risk factors and 180-day postoperative mortality in type a aortic dissection: a cohort study

To explore modifiable risk factors associated with 180-day postoperative mortality based on preoperative examinations in patients with type A aortic dissection. From August 2021 to November 2024,86 patients with TAAD attending the Emergency and Trauma Center of the First Affiliat...

A comprehensive assessment of tandem repeat genotyping methods for Nanopore long-read genomes

Tandem repeats play critical roles in human disease and phenotypic diversity but are among the most challenging classes of genomic variation to measure accurately. Long-read sequencing has the potential to accurately characterize long and complex tandem repeats. While an increasi...