Research works

Euclidean Condensate Theory (ECT): Emergence of Spacetime, Quantum Mechanics, and Gravity from Spontaneous O(4) Symmetry Breaking

Euclidean Condensate Theory (ECT) is a research programme asking whether physical time, Lorentzian propagation, quantum structure, and gravitational response can arise as effective sectors of a medium defined initially on a four-dimensional Euclidean carrier. Its minimal concrete...

Cold snare polypectomy versus conventional endoscopic mucosal resection for colorectal polyps 15 mm or smaller: delayed bleeding and resection outcomes in a retrospective cohort

Guidelines recommend cold snare polypectomy (CSP) for colorectal polyps 10 mm or smaller, but data for larger polyps are limited. We compared delayed post-polypectomy bleeding (DPPB) and resection outcomes after CSP versus conventional endoscopic mucosal resection (EMR) for polyp...

EuroMillions Breakthrough Mining — 1338 Sources, 8890 Leads Extracted — E8 Intelligence Research

Mined 1338 lottery+quantum breakthroughs. Extracted 8890 leads across 13 categories. 7000 high-value leads found. Categories: {"CORRIDOR": 718, "FORMULA": 573, "GEOMETRIC": 672, "FORWARD_ATTEMPT": 748, "QUANTUM": 961, "TIMING": 174, "CELESTIAL": 659, "GEMATRIA": 705, "CONSTANT":...

Navigating the Neurological Fog: A Framework for Understanding and Managing Clinical Uncertainty in Adult Medical Education

ABSTRACT Clinical reasoning uncertainty is an inescapable reality in medicine, and its impact is uniquely amplified in neurology. This article proposes a framework for integrating clinical reasoning and uncertainty into adult medical education, using neurology as a model for tran...

Identification and characterization of PldB domain-containing esterase from a freshwater pond metagenome

Esterases, a class of α/β-hydrolases, are crucial enzymes used for the biotransformation of industrially important biomolecules. Exploring the pond metagenome, a lipolytic clone. (PLR5) was identified that exhibited activity against tributyrin. This clone encodes a unique putativ...

HIF1A-dependent induction of alveolar miR-147b dampens SARS-CoV-2-associated ARDS via direct targeting of viral RNA

BACKGROUND: Acute respiratory distress syndrome (ARDS) causes significant morbidity and mortality during viral pneumonia, including SARS-CoV-2 infections. Nevertheless, most patients with SARS-CoV-2 infections recover seamlessly without developing ARDS, suggesting the existence o...

Unconditional Global Stability of Solutions to High-Dimensional Parabolic-Elliptic Coupled System: Initial-Boundary Value Problem

Abstract. This paper demonstrates the unconditional global stability of solutions to the initial-boundary value problem for a parabolic-elliptic coupled system in the two-dimensional or three-dimensional half-space. It is shown that as time approaches infinity, the solution conve...

Direct atomistic simulation of dislocation climb in fcc Ni

Dislocation climb is one of the key processes controlling the mechanical response and microstructure evolution of materials at high temperatures. The mechanisms of this phenomenon are still unclear due to its complex nature, which involves interactions between point defects and d...

Mathematical Foundations of the Dipole-Wave Ontology: Reduction to the Schrödinger Equation and Bohmian Guidance

Abstract: A previous paper by Arneberg [1] proposed a local, deterministic ontology in which all fundamental particles are point-like entities possessing an intrinsic oscillating dipole moment that radiates a real guiding wave. That paper presented the conceptual framework and a...

Directional Discriminant Packets and Bounded Scalar-Profile Loci for Primitive Binary Quadratic Germs

Let $q=a u^2+2buv+c v^2\in k[[x,y]]\otimes\Sym^2(V^*)$ be a primitive binary quadratic germ over an algebraically closed field of characteristic zero, and let $D=\Disc(q)=b^2-ac$. Along a chosen path of point blowups, the lowest $\Sym^2(V^*)$-valued coefficient packets and the sc...

Externally Validated Plasma Phospholipid Panel for Pneumoconiosis Triage Across Dust-Exposed and Unexposed Worker Cohorts

Objective: To evaluate whether targeted plasma phospholipidomics identifies an externally validated blood panel for pneumoconiosis triage across dust-exposed and nonexposed worker cohorts. Methods: We quantified 53 plasma phospholipids by UPLC-MS/MS in discovery (n=392) and exter...

Genetics and the Genome: Inheritance and Variation of Information Topology (Volume II of the Axiomatization of Biology in the Global‑Realism Framework) Abstract

This second volume of the global‑realist biology program derives genetics as a lawful continuation of already closed physical, chemical, and first‑biological layers. Without introducing “gene”, “allele”, “recombination”, or “genome” as primitive terms, we construct them from sequ...

Outcome Coordination for AI Agents

Outcome Coordination for AI Agents presents an architectural model for governing AI-agent execution within individual systems while coordinating outcomes across organizational and technical trust boundaries. The paper shifts the agent-facing abstraction from low-level tool calls...

E8‑Phi Adaptive Leak Correction (ALC) for Neural Hyperdimensional Encoding — E8 Intelligence Research

The E8 lattice's 240 root vectors constitute an 8‑dimensional reference frame that, when continuously rotated by a phi‑modulated 132 Hz pulse, generates a dynamic leak‑inversion field across neuronal ensembles. This field aligns the high‑dimensional entanglement patterns of neura...

Jomon Zero-Dimensional Space

Definition 1. A zero-dimensional space is a zero point. A zero point is not the origin of a coordinate system.

Nigeria's Border Communities: Navigating Challenges and Fostering Inclusive Development

This study, "Nigeria's Border Communities: Navigating Challenges and Fostering Inclusive Development," explores the complex issues confronting border communities in Nigeria and identifies strategies for promoting inclusive development. The research highlights the unique challenge...

Emergent Cosmological Intervals from Ultralight Bose-Einstein Condensates in Modified Measure Theory

We present a rigorous mathematical synthesis of Modified Measure Theory (MMT) and the cosmology of ultralight Bose-Einstein Condensates (BEC). By identifying the phenomenological "measure field" of standard MMT as the macroscopic wavefunction of a cosmological BEC, we naturally d...

Tackling Waste of Fruits and Vegetables in Chilean Households with Tailored Informational–Enablement Interventions: A Randomized Controlled Pilot Study

Randomized Controlled Trials (RCTs) and direct measurement of waste are the gold standards for evaluating food waste interventions. This pilot RCT explored the effects of a 3-week tailored informational–enablement intervention to reduce the causes and amount of fruit and vegetabl...

Machine Learning-Guided Stress Atlases Reveal Co-Expression Rewiring and Divergent Cellular Deployment of Abiotic Stress Programs in Rice and Wheat

Abiotic stress limits cereal productivity, yet whether conserved stress-responsive genes retain similar transcriptional network organization and cellular deployment across cereal species remains unknown. Here, we developed a machine learning-guided comparative framework to integr...

Global and Transnational Governance of Out-of-home Childcare: Towards a Theorisation of Cross-border Agency in Child Institutionalisation

This article aims to contribute to framing and theorising of cross-border processes affecting residential childcare, specifically the institutionalisation of children. Existing studies of global trends around child institutionalisation tend to have two limitations. They either pa...