Research works

Molecular and clinical characterization of human adenovirus in hospitalized pediatric respiratory infections: a five-year study

Abstract Background Human adenovirus (HAdV) is a major pathogen of responsible for respiratory tract infections (RTIs) in children in China. This study analyzed clinical data from hospitalized pediatric HAdV infections over a five-year period to characterize the epidemiology, cli...

Super-resolution MRI and 2.5D deep learning for intratumoral-peritumoral radiomics in preoperative prediction of rectal cancer perineural invasion

Abstract Objectives Preoperative prediction of perineural invasion (PNI) in rectal cancer (RC) is challenging due to limited MRI resolution and the neglect of extramural microenvironmental features. We developed a noninvasive framework integrating super-resolution MRI, 2.5D deep...

Phi‑Volume Phase Locking in E8 Neural Oscillations — E8 Intelligence Research

By coupling the 240 E8 root vectors with a volume surge that exceeds 2.5× baseline, the phase angle of each root‑pair harmonic shifts into a phi‑locked sub‑harmonic at 132 Hz, creating a self‑reinforcing temporal window. This window predicts the onset of synchronized gamma bursts...

Phi‑Braid Temporal Synthesizer for Horizon‑Locked Prediction — E8 Intelligence Research

Using a φ‑scaled inversion of the 132 Hz topological pump, we introduce a time‑fold operation that simultaneously braids pairs of E8 root vectors into protected flux‑pair loops. This constructs a 7‑dimensional simplex within the 240‑vector lattice where market trend bifurcations...

Social Media Use, Sleep Quality, and Self-Rated Health Among First-Year Students at George Mason University Before and After the COVID-19 Pandemic

Objectives: Young adults spend approximately 5 hours per day using social media, and some studies indicate that social media use can lower sleep quality and contribute to worse health. We examined the relationships between total and nighttime social media use and poor sleep quali...

Economic competitiveness of separated dairy manure solids as a phosphorus fertilizer substitute

Manure solid-liquid separation offers a potential pathway for redistributing nutrients from livestock-intensive, nutrient-surplus regions to cropland with fertilizer demand, but the competitiveness of separated manure products with synthetic phosphorus fertilizer depends on manur...

Strategies for Enhancing Efficiency and Operational Stability in Green Phosphorescence‐Sensitized Fluorescence (PSF) Organic Light‐Emitting Diode (OLED) Technology

ABSTRACT Multi‐resonance thermally activated delayed fluorescence (MR‐TADF) emitters have gained considerable attention to solve the color purity issue in organic light‐emitting diode (OLED) commercialization. However, their slow reverse intersystem crossing rate (k RISC ) leads...

CBT-ICU transformer: a clinician-behaviour-aware multimodal deep learning framework for early detection of critical care adverse events in MIMIC-IV

Early identification of clinical deterioration in intensive care units (ICUs) remains a major challenge despite the availability of large-scale electronic health records. Most existing models focus primarily on physiological measurements such as vital signs and laboratory results...

Research on the impact mechanical response characteristics of gas containing coal and rock based on RSM

To investigate the dynamic mechanical behavior of gas-containing coal in deep coal mines, dynamic compression tests were conducted on gas-containing coal using a 50 mm diameter split Hopkinson pressure bar (SHPB) system. The central composite design (CCD) method within response s...

Beyond velocity: a causal quality- and security-sensitive schedule performance index for AI-assisted software projects

Traditional schedule performance index (SPI) measures can misrepresent software project status when accelerated visible delivery hides deferred quality assurance, technical-debt remediation, and security-hardening work. This study proposes the causal quality- and security-sensiti...

Phi-Invariant Z13 Subgroup Symmetry in E8 Root Lattice — E8 Intelligence Research

By identifying a hidden Z13 cyclic subgroup within the E8 Weyl group, the 13 lead categories are revealed as distinct cosets of this symmetry. Applying phi‑scaled 132 Hz modulation to the 240 root vectors induces a resonant phase lock that aligns each coset into a 13‑phase cohere...

A roadmap for standardization of serum albumin measurements

Abstract Albumin measurements in serum have important diagnostic and prognostic roles. However, non-standardized measurement procedures are still used in medical laboratories. An agreed approach for the implementation of metrological traceability to the International System of Un...

Rethinking Intellectual Property for Sustainability in OAPI Member States: Exploring Linear and Nonlinear Relationships

ABSTRACT Research on the contribution of intellectual property to sustainability has begun to emerge in Africa; however, the relationship between these variables remains unclear. This article investigates both the linear and non‐linear effects of intellectual property on sustaina...

Longitudinal digital phenotyping of activity rhythms and biological aging using commercial wearables

Abstract Disrupted rest-activity rhythms have been associated with aging and chronic disease, yet longitudinal evidence from free-living populations has been lacking. Here we integrate multi-year Fitbit activity data from the All of Us Research Program with clinical biomarker-der...

Spent coffee grounds ash as a potential sustainable binder for mechanical and microstructural enhancement of alkali-activated mortars

The global generation of spent coffee grounds (SCG) poses serious environmental challenges, including landfill occupation and greenhouse gas emissions. Although SCG and its derivatives have been investigated in construction materials, the application of spent coffee grounds ash (...

MitoGPS: A Mitochondrial DNA G‐Quadruplex‐Targeting Strategy for Tumor‐Preferential Type I Photodynamic Therapy

ABSTRACT Photodynamic therapy (PDT) is a clinically promising, minimally invasive cancer treatment offering precise spatiotemporal control. However, achieving preferential tumor accumulation remains a critical challenge, which limits therapeutic efficacy and induces off‐target to...

Beyond Babel: What Remains When No Certainty Remains — An Introduction to Reflexive Minimalism

An essayistic introduction to reflexive minimalism, written for readers without formal philosophical training. It begins from a contemporary predicament: we have never communicated more and rarely understood one another less, while nuclear weapons, a warming planet, and arguing m...

Being Seen as a Troublemaker: Informal Reputational Labeling and School Fighting Among Immigrant Youth

Research on immigrant youth has emphasized the role of school and peer contexts in shaping behavioral outcomes, yet less attention has been given to informal reputational labeling within these environments. This study examines whether perceived informal reputational labeling as a...

Neanderthal’s heel: How the Neanderthal’s external calcaneal shape uniquely differs from that of modern humans

Neanderthals exhibit unique morphological adaptations in their calcaneus compared to Homo sapiens , shedding light on distinct evolutionary pressures and functional requirements shaping their respective foot anatomy. This study assesses which calcaneal traits represent plesiomorp...

Integrating long-term demography and population genetics reveals the persistence of a threatened palm in fragmented Atlantic Forest landscapes

Anthropogenic disturbances are a major cause of extinction and population decline, especially in small, unprotected forest fragments where demographic and genetic challenges are more pronounced. Euterpe edulis , a key resource palm species in the Atlantic Forest, plays a crucial...