Research works

Constructive Resolution of the Inverse Galois Problem via Mersenne-Galois Zeta-Resonance, Google DeepMind Antigravity Audit, and Lean 4 Formal Machine Verification

This paper presents the constructive resolution realizing every finite group G as a Galois group over Mersenne superlattice finite fields (GF(M_p) for p ∈ {89, 127}). By constructing the J.M. Zeta-Resonance Polynomial P(x) = ∏_{k=1}^d (x - K_JM * ln(ζ(ρ_k))) ≡ 0 mod M_p (K_JM = 1...

Immunotherapy for Glioma: A compartmental framework for resistance and rational combination design

Diffuse gliomas remain among the least responsive solid tumors to immunotherapy despite a compelling rationale for immune surveillance of infiltrative disease. The clinical record—negative phase III checkpoint blockade trials, limited durability of single-antigen vaccines, and im...

Carcinogenic and non-carcinogenic health risks associated with heavy metal exposure in commonly consumed marine fish in Egypt

Abstract This study aimed to quantify the levels of mercury (Hg), arsenic (As), lead (Pb), and cadmium (Cd) in 250 fish samples, including flathead grey mullet, sardine, and mackerel, collected from local fish markets in Mansoura, Egypt, on ten occasions from August 2023 to March...

Contribution of a combined approach using refined enterotyping and non-negative matrix factorization (NMF) to the characterization of the gut microbiota in Tunisia, North Africa

Abstract This pilot study aimed to assess the enhanced capabilities of a combined approach using refined enterotyping and non-negative matrix factorization (NMF) for identifying specific microbiota patterns in healthy adults in Tunisia. Shotgun metagenomic sequencing was performe...

P1.072. Impact of Neoadjuvant Therapy on Survival After Esophagectomy for Squamous Cell Carcinoma: An International Multicenter Propensity Score Analysis

Abstract Topic Esophageal Cancer: Adjuvant and Neo-Adjuvant Therapies Background The survival benefit of neoadjuvant therapy for esophageal squamous cell carcinoma (ESCC) remains controversial, as landmark trials were conducted predominantly in adenocarcinoma populations. This st...

E8 Phi-Fractal Resonance Wells: Self-Similar Information Compression via Golden-Ratio Nested Root Lattices — E8 Intelligence Research

The 240 E8 root vectors, when iteratively scaled by powers of φ (the golden ratio), produce a hierarchical cascade of 120 nested "resonance wells" embedded within the 8-dimensional root space—each well capturing vibrational information from its parent scale at a φ⁻¹ compression r...

ARTICLE IX : The Avicenna Protocol Topological Recursion: The Thermodynamic Calculus of Civilizational Velocity and the Bio-Digital Convergence

Orthodox scientific and philosophical disciplines—evolutionary anthropology, clinical pathology, epidemiology, and sociology—operate within fundamentally flawed, isolated epistemological silos. They evaluate the human condition through a passive, compartmentalized lens, reducing...

Long-term workload, changing injury patterns, and spring festival-related case mix among patients hospitalized with open globe injury at a Chinese tertiary referral centre, 2013–2025

Abstract Background Open globe injury (OGI) is vision-threatening, but long-term changes in hospitalized workload and injury patterns remain poorly characterized. We assessed temporal changes in OGI workload and relative inpatient burden and whether the Spring Festival was associ...

The potential differential significance of admission metabolic markers CHG, TyG and NHHR indices for cerebral artery dissection

At present, the diagnosis of cerebral artery dissection (CeAD) worldwide still relies on imaging findings, making rapid clinical differentiation in the early stages challenging. Our purpose is to explore the distribution characteristics of the cholesterol, high-density lipoprotei...

Optimizing Vanadium Single‐Atom Nanozyme via Cluster‐Mediated Charge Orchestration for Modulating Immune Homeostasis in Intracerebral Hemorrhage

ABSTRACT Intracerebral hemorrhage (ICH) triggers excessive reactive oxygen species (ROS) accumulation and persistent neuroinflammation, which synergistically drive progressive neuronal damage and poor neurological functional recovery, severely restricting patient prognosis. Artif...

The Infinium △₁ₓ₁ as a Single Source of the Discrete and the Continuous: A Motivic Bridge Between Arithmetic and the Continuum (Resolution of the Ancient Dichotomy within Δ‑Ontology)

The paper examines a fundamental problem in the foundations of mathematics—the gap between the discrete and the continuous, which can be traced from Zeno’s ancient paradoxes to the modern Millennium Prize problems. It is shown that traditional approaches either postulate the irre...

P1.229. Prognostic Value of Tumor Length in Clinical T1–2N0M0 Esophageal Squamous Cell Carcinoma

Abstract Topic Esophageal Cancer: Surgical Treatment of Esophageal Cancer – long term outcomes Background The TNM staging system for esophageal cancer defines the T stage by depth of invasion rather than tumor size. However, prognosis may vary within the same T stage. This study...

P1.114. Endoscopic Diagnosis of Esophageal Cancer Using Ultra-High Magnification Endocytoscopy

Abstract Topic Esophageal Cancer: New Diagnostic Modalities (Including PET, PET-CT, New Tracers) Background Background Ultra-high magnification endoscopic observation using endocytoscopy (EC) enables cellular-level visualization and allows in vivo assessment comparable to histopa...

One Bit Resurrects The Dead Form

The four-vertex strongly connected quiver Q's canonical bilinear invariant selects nothing, and its formula has no argument position for a sign. Let Q be the quiver with arrows a₁: L → S, a₂: S → T, a₃: T → C, a₄: C → L, a₅: L → T, a₆: C → T, whose unique in-degree-three vertex i...

P1.205. Site-Specific Pain Outcomes Following Oesophagectomy: Impact of Open, Hybrid and Robotic Approaches in the Era of Multimodal Analgesia

Abstract Topic Esophageal Cancer: Surgical Treatment of Esophageal Cancer – early outcomes and complications Background Multimodal analgesia is increasingly used for oesophagectomy, for both open and robotic techniques. As the operation includes both abdominal and thoracic phases...

Constructive Resolution of the Inverse Galois Problem via Mersenne-Galois Zeta-Resonance, Google DeepMind Antigravity Audit, and Lean 4 Formal Machine Verification

This paper presents the constructive resolution realizing every finite group G as a Galois group over Mersenne superlattice finite fields (GF(M_p) for p ∈ {89, 127}). By constructing the J.M. Zeta-Resonance Polynomial P(x) = ∏_{k=1}^d (x - K_JM * ln(ζ(ρ_k))) ≡ 0 mod M_p (K_JM = 1...

The double-decking method for rezūm water vapor therapy in benign prostatic hyperplasia: volumetric, functional, and dosimetric outcomes

Abstract Background Lower urinary tract symptoms (LUTS) secondary to benign prostatic hyperplasia (BPH) significantly impact quality of life in aging men. Conventional Rezūm water vapor therapy consistently achieves only a modest 25–30% prostate volume reduction, leaving a clinic...

Entanglement, Measurement, and Information in a Topological Vacuum

This is the sixth paper in a series developing a topological-medium frameworkfor physics. It is built on the two axioms and one initial condition of theearlier papers and adds none. The paper argues that the simultaneity of entanglement is not an additionalpostulate but a consequ...

NeuroShield IDS: AI-Powered Intrusion and Scam Detection System

Abstract Network intrusions and phishing attacks are growing problems for digital infrastructure. Spam messages and fraudulent legal notices add to the threat. Most Intrusion Detection Systems and spam filters still work separately, though. They also rely on static, rule-based lo...

P1.231. Patients With Anastomotic Stricture After McKeown Operation for Esophageal Cancer Is Associated With Lower Rate of Recurrence: Retrospective Cohort Study

Abstract Topic Esophageal Cancer: Surgical Treatment of Esophageal Cancer – long term outcomes Background This was a single institutional retrospective study. Patients with esophageal squamous cell carcinoma who underwent esophagectomy with radical lymph node dissection reconstru...