Research works

16S rRNA sequencing of subgingival plaque microbiomes in RA patients by ACPA status and healthy controls

This project investigates the subgingival plaque microbiome in patients with rheumatoid arthritis (RA) and healthy controls using 16S rRNA gene amplicon sequencing of the 338F-806R region. The dataset comprises 64 subgingival plaque samples collected in China, including 28 sample...

Silent Trauma: Implications of Non-Fatal Strangulation-Acquired Brain Injury — An Integrative Review

Non-fatal strangulation (NFS) is a severe form of Intimate partner violence (IPV) that can result in acquired brain injuries (ABI), yet this link is frequently overlooked. Misdiagnosis and limited awareness contribute to long-term physical and mental health complications. Evidenc...

Fixed-cycle oral pomalidomide/lenalidomide-based therapy is associated with durable treatment-free remission in idiopathic multicentric castleman disease with TAFRO syndrome: a single-center retrospective study

Abstract Background Idiopathic multicentric Castleman disease with TAFRO syndrome (iMCD-TAFRO) is a rare and severe subtype of iMCD characterized by thrombocytopenia, anasarca, fever, reticulin fibrosis, and organomegaly. Current treatments often require prolonged or indefinite a...

Sequential patterns of challenges and socially shared regulation of learning: a comparison of pre-service and in-service teachers’ collaborative learning

Abstract Socially shared regulation of learning (SSRL) can promote high-level collaborative learning. However, the sequential interplay between sociocognitive, socioemotional and motivational group-level challenges and SSRL strategies remains unclear, particularly in comparative...

Development and validation of a self-report questionnaire to assess executive functions in healthy adults: the executive functions in healthy adults questionnaire (EFHAQ)

Abstract Aim of this research was to develop and validate a time-efficient, ecologically valid self-report questionnaire measuring executive functions in healthy adults, grounded in the unity/diversity framework of Miyake (i.e., inhibition, updating, shifting). Across a pre-study...

Perception of patients with temporomandibular disorders of the effects of botulinum toxin application: a retrospective cross-sectional observational study

OBJECTIVE: To evaluate patient-reported changes in orofacial and masticatory symptoms after BoNT-A application in individuals presenting bruxism-related complaints. MATERIALS AND METHODS: A retrospective cross-sectional observacional study was conducted with 61 adult participants...

Reluctant Revolutionaries: Andor, Fallout, and Narrating the Shifting Moral Economy of Armed Politics in the United States

Abstract This contribution to the special issue of the Forum argues that mainstream science fiction can be an important site for narrating a nascent change in the moral economy of armed politics in the United States. While firearm politics remain durably partisan, I show that a n...

Lived Experiences of Senior High School (SHS) Teachers in Producing NC II Holders

Abstract Technical-vocational education provides socially relevant pathways for skills formation, certification, and workforce participation among Senior High School learners. This phenomenological study explored the lived experiences of Senior High School teachers in producing N...

Pricing semi-cooperation in unstable linear–linear bilevel programs via strictly convex tie-breaking and stability contracts

Abstract When the follower problem in a bilevel program admits multiple optimal solutions, the leader’s outcome depends on how ties are resolved. This yields the classical optimistic/pessimistic ambiguity and makes the model unstable (ill-posed) from a predictive viewpoint. We st...

Mathematics Self-Efficacy: Its Relationship to Student Mathematics Achievement

Abstract Mathematics self-efficacy is a socially relevant educational construct because students’ beliefs about their mathematical capability can shape participation, persistence, and achievement in learning environments. This descriptive-correlational study examined mathematics...

PUH Theorem 320 (The Missing Coupling Term) — Symmetry Forces the Nearest-Neighbour Energy; the E8 Lattice Is Isotropic to SIXTH Order Because It Has No Degree-4 or Degree-6 Casimir; and Directional Lorentz Violation Falls to (a/λ)⁶

Photonic Universe Hypothesis (PUH) — Postulate and Consequences. THE GAP IS SINGULAR, NOT PLURAL. T298's audit recorded that T175's Lagrangian contains NO SPATIAL DERIVATIVES — no gradient term, no dependence on x — and is constrained optimization at a point in the 248-dimensiona...

Robust Static Candidate-Branch Obstructions and Reduced Pole-Correction Bounds in a Chiral Operator-Spectral Framework

We study a supplied chiral operator-spectral branch in which a common positive spectral scale multiplies four Hermitian family quadratic forms relative to a common family metric. Conservative mass ratios and static spectral subspaces are invariant under common positive rescaling,...

Proof-of-concept validation of p2GUS, a modular expression system for enhanced Ni-binding purification of functional recombinant proteins in Escherichia coli

Abstract Protein expression and purification remain critical steps in basic research, biotechnology, and industrial applications. Here, p2GUS, a modular Escherichia coli expression system generated through targeted modification of Precursor 1, a parental pBAD-derived vector, is d...

Macroscopic Quantum Coherence at 300 K and Many-Worlds Bifurcation in the Exciton-Polariton Soliton:from the direct soliton–Schrödinger mapping to admissible branch selection

This paper addresses a foundational question in quantum mechanics: can an effective Hilbert subspace describing a macroscopic collective degree of freedom take the place of the single photon in the double-slit experiment while retaining full mathematical consistency? The answer i...

FOCUS: a feature optimization and cascaded unified screening strategy for computer-aided pathology-based glioma molecular subtype classification

Abstract Background Accurate classification of Isocitrate Dehydrogenase (IDH) mutation status is crucial for the diagnosis and treatment of adult-type diffuse gliomas as defined by the 2021 World Health Organization (WHO) Classification. However, conventional histological and mol...

Serial dual-wavelength illumination for retinal vessel oximetry using a conventional fundus camera: a proof-of-concept study

Abstract Purpose Retinal vessel oximetry requires fundus images at two wavelengths with different hemoglobin absorption characteristics. Simultaneous acquisition using one-chip color cameras may be affected by incomplete spectral separation of detector channels, whereas multi-chi...

Equitable ARAL Program Implementation in Philippine Public Schools

Abstract The Academic Recovery and Accessible Learning (ARAL) Program is a national learning recovery initiative designed to support Philippine learners who struggle in reading, mathematics, and science. This policy-oriented synthesis examines equitable ARAL Program implementatio...

VEGFR signalling and hemoptysis: mechanisms, critical appraisal of the evidence, and the double-edged role of VEGFR-2 inhibition — a narrative review

Abstract Hemoptysis is a potentially life-threatening manifestation of pulmonary disease, including lung cancer, bronchiectasis and pulmonary tuberculosis. Critically, in approximately 90% of cases the bleeding arises from the high-pressure bronchial (systemic) arterial circulati...

Pollution assessment and source analysis of heavy metals and nutrients in sediments of Liujiaxia reservoir, upper Yellow River, China

Abstract To investigate the pollution characteristics, ecological risks, and sources of nutrients and heavy metals in the sediments of the Liujiaxia Reservoir, 21 surface sediment samples were collected in August 2025. Concentrations of total nitrogen (TN), total phosphorus (TP),...

Real-Time Fraud Detection in Mobile Payments: Behavioral Biometrics and Transaction Anomaly Fusion

Research article: Real-Time Fraud Detection in Mobile Payments: Behavioral Biometrics and Transaction Anomaly Fusion