Research works

Importance of very low proteinuria levels in immunoglobulin A nephropathy: evidence of a non-linear association with long-term kidney survival

Abstract Background Proteinuria is a major predictor of disease progression in immunoglobulin A nephropathy (IgAN), and lower levels are associated with more favorable kidney outcomes. Prior studies have largely evaluated proteinuria using predefined categories (e.g., < 0.5 g/d;...

The SR Ultiverse Charter: Unified Architecture of Substrate, Meaning, Agency, Experience, and Value

The SR Ultiverse is the completed top-level architecture of SignalRupture. It connects three master fields without reducing one to another. Infrastructure Science studies the substrates that make functions possible and govern drift, collapse pressure, propagation, debt, human loa...

Static and dynamic biomechanical responses of the lumbar spine under different loads: A finite element study

Lumbar spinal loads differ across various scenarios, including lumbar extension in the lateral recumbent position, seated/standing trunk extension, upright sitting or standing, muscular tension, muscular relaxation, and whole-body vibration. Nevertheless, systematic comparative s...

A Novel Neurodynamics-Based Approach to Fatigue-Aware Motion Planning in Human–Robot Collaborative Assembly

This paper proposes a neurodynamics-based motion planning framework for fatigue-aware human–robot collaborative assembly (HRCA). The proposed framework integrates human fatigue information into robot motion planning to generate fatigue-dependent trajectories with adaptive clearan...

An online learning resource in support of the recruitment of people living with dementia and their carers to research

Although the number of people diagnosed with dementia is increasing globally, it is estimated that only 2% are engaged in dementia research in the UK. In part, this may be due to a lack of confidence on the part of health and social care professionals to discuss research opportun...

Replication package for "AI, Structural Power and Governance Fragmentation: A Systematic Review and the Geopolitical AI Power Framework"

Replication package for a PRISMA 2020 systematic review on artificial intelligence and structural power in the global political economy. It contains the exact Scopus and Web of Science queries (5 October 2026) and record counts per stage; the screening decisions for 1,199 dedupli...

THE SANNER MODEL – Towards an Evolution Equation for the Aether Field

The Sanner Model (TSM) postulates a rigid, three-dimensional space filled with a massless, frictionless, density-free aether that accelerates radially inward toward mass centers. The foundation document presented the field equation as a static constraint: it determines the aether...

Immune Biomarkers of Islet Transplant Rejection Revealed by Synthetic Immunological Niche

ABSTRACT Islet transplantation can restore glycemic control in type 1 diabetes, yet heterogeneity of immune responses and transplant outcomes necessitates improved graft monitoring. Since transplanted islets are diffusely engrafted within the liver and inaccessible to biopsy, cli...

Screening and identification of significant media components using Plackett–Burman design for enhanced extracellular protease production by Bacillus sp. MTCC 511 under mutagenic stress conditions

Abstract Background Statistical screening of media components is essential for identifying the key variables that govern protease yield from Bacillus species. We used a 12-run Plackett–Burman Design (PBD) to screen ten independent variables—dipotassium phosphate, monopotassium ph...

Switchable Electroosmotic Delivery via Capillary Shrunken Reduced Graphene Oxide Membrane

Abstract A capillary-force-assisted reduced graphene oxide (rGO) membrane is developed for electrically controlled electroosmotic flow (EOF). By combining capillary drying with subsequent freeze-drying, structural shrinkage is used to continuously control the pore size and channe...

From Space Renewal to Relationship Renewal: Facilitation of Co-Design

As community renewal increasingly emphasizes the roles of various participants in decision-making and operations, relationship renewal is gaining greater attention as an outcome of community renewal. Achieving relationship renewal requires consideration of long-term processes and...

Effects of Different Nitrogen Application Rates on Growth, Photosynthetic Characteristics, Yield, and Nitrogen Use Efficiency of Zizania latifolia

To promote the growth, photosynthetic capacity, yield and nitrogen use efficiency (NUE) of Zizania latifolia, optimizing the amount of nitrogen (N) fertilization applied is critical. We investigated the effects of different nitrogen application rates on the growth, development, p...

Harnessing Indigenous Knowledge for Climate-Smart Agri-Food Systems: A Review of Adaptation Strategies, Food Security, Ecosystem Services, Governance, and Digital Innovation in Sub-Saharan Africa

Sub-Saharan Africa (SSA) faces escalating climate challenges that threaten agricultural productivity, food security, ecosystem sustainability, and rural livelihoods. Indigenous knowledge (IK), developed through generations of interaction with local environments, offers context-sp...

Does the Pilot Long-Term Care Insurance Work as Expected in China? Examining its Impact on Hospital Utilizations, Medical Expenses, and Health

This study investigates the impact of long-term care insurance (LTCI) on older adults’ hospital service utilization, medical expenses, and health. Using national representative data from four waves of CHARLS (2011, 2013, 2015, 2018), we find that LTCI decreases older adults’ mont...

Performance of Large Language Models in Answering Juvenile Systemic Lupus Erythematosus Questions: A Blinded Expert-based Comparative Study

Background: Large language models are increasingly used to obtain medical information, but their performance in juvenile systemic lupus erythematosus remains insufficiently characterized. Objective: To compare expert-rated response quality and clinical relevance across 4 artifici...

Coal-Body Structural Evolution, Multiscale Pore-System Reorganization, and Methane Storage-Transport Characteristics Across a Tectonic Deformation Gradient

Tectonic deformation can reorganize adsorption-related pores, matrix pore space, and pore-throat-fracture networks, but how these functional domains jointly govern fluid mobility and permeability stability under stress remains unclear where deformation intensity and coal rank cov...

Understanding Goal Selection Through Human Limitations

Abstract From climbing mountains to playing video games, people have a striking ability to make a goal out of just about anything. However, people do not choose their goals haphazardly. Instead, they often rely on previously chosen goals to inform the ones they choose in the futu...

Topological Self-Locking of Hyperbranched Poly(ionic liquid)s for Impact-Stiffening Ionic Skins

Abstract Impact-stiffening ionic skins are highly promising for bioelectronics due to their unique ability to maintain ambient softness and ionic conductivity while instantly hardening upon impact. However, the intrinsically low entropy penalty of ionic bonds typically restricts...

MR Neurography of Fine-Caliber Nerves: Technical Considerations and Practical Applications

With the advent of high-resolution imaging techniques, advanced fat and vascular suppression methods, and three-dimensional isotropic acquisitions, MR neurography of fine-caliber nerves has become an indispensable tool in assessment of peripheral neuropathies, but successful imag...

The contribution of Caribbean medical schools to the U.S. physician workforce

Abstract Purpose The physician shortfall in the U.S. has given rise to increasing reliance on international medical school graduates (IMGs), including those graduating from what are referred to as off-shore Caribbean medical schools. These schools, which offer instruction in Engl...