Zhengzhou University

StructuralDiversity and Multicenter Bonding in Beryllium–OsmiumIntermetallic Compounds

Abstract Beryllium intermetallic compounds (beryllides) have attracted considerable interest for applications relevant to nuclear systems, refractory materials, and aerospace systems due to their exceptional physical properties. In this work, crystal structures of osmium beryllid...

Stress-State-Dependent Reinforcement of Cement-Stabilized Soil Using Waste Brick Powder and Glass Fiber

Cement-stabilized soil is widely used for ground improvement but suffers from brittleness and low tensile strength. This study investigates combined modification of cement-stabilized soil with waste brick powder (WBP, 5%) and glass fiber (GF, 0–2.0%) to enhance mechanical perform...

Solid‐Phase Engineered Metal‐Free Carbonized Polymer Dots With Auto‐Generated Rigid Amorphous Network Enabled High‐Temperature Liquid‐Phase Phosphorescence

While organic phosphorescent materials hold immense promise, their application is severely hampered by limited emission tunability, short lifetimes, and environmental instability. Herein, we report a facile solid-phase engineering strategy to achieve the large-scale synthesis of...

Analysing Lost Highway as a Non-deterministic Narrative Structure: Initiating Déjà Vu-like Recognition to Establish Non-causal Linkage

This article examines how repetition produces déjà vu-like recognition in non-deterministic narrative cinema. Focusing on David Lynch’s Lost Highway (1997), it argues that the film’s repetitions do not lead to conventional repetition–resolution, but instead organise an entangled...

Osimertinib With or Without Chemotherapy in Advanced Non–Small Cell Lung Cancer With EGFR and Concurrent TP53 Mutations

Importance: Combination therapy has emerged as a promising therapeutic approach for patients with epidermal growth factor receptor (EGFR)-mutated non-small cell lung cancer (NSCLC). However, its clinical benefit-risk profile remains a focus of ongoing debate. Identifying patients...

Influence of Composite Mineral Admixtures and Expansive Agent on the Mechanical Properties, Durability and Microstructure of Cementitious Materials

To improve volume stability and durability of cementitious materials, a composite mineral admixture including ground granulated blast furnace slag, fly ash and silica fume was incorporated at a fixed 12% replacement ratio together with varying dosages of an expansive agent (EA)....

Leakage Identification in Water Distribution Networks Based on Physics-Based Joint Inversion and ExtraTrees Candidate Re-Ranking

Leakage identification in water distribution networks must estimate leak locations and magnitudes under demand fluctuations, similar adjacent-node responses, and superimposed multiple-leak signals. This study combines physics-based joint inversion with ExtraTrees candidate re-ran...

Treatment of Acute Ischemic Stroke with Intravenous Urokinase (TASK-UK): Protocol for a Multicenter, Prospective, Real-World Study

Intravenous thrombolysis with recombinant tissue plasminogen activator (rt-PA) and urokinase (UK) are both recommended for acute ischemic stroke (AIS) in China. Compared with rt-PA, UK is less expensive and more widely available in clinical practice. The Treatment of Acute Ischem...

Charge-Transfer Engineering in 0D/3D Rare-Earth Halide Heterostructures Enables Tunable and Efficient White Light-Emitting Diodes

Abstract Lead-free rare-earth metal halides hold great promise for solid-state white-light LEDs, yet efficient and spectrally tunable white emission remains challenging. Herein, we adopt an in situ alloying strategy with Ag+ ions to design and synthesize a 0D/3D (Cs3LuCl6/Cs2AgLu...

Biobased Fibrous Films Enabling Synergistic Thermal Conduction and Radiative Cooling for Personal Thermal Management

Abstract Personal thermal management materials are increasingly in demand under intensifying outdoor heat exposure and global warming. However, simultaneously achieving efficient radiative cooling, rapid thermal conduction, mechanical flexibility, and sustainability within a simp...

Joint effects and mediating mechanisms of body roundness index and biological aging on the risk of incident cardiovascular disease: a nationally representative prospective cohort study

Body roundness index (BRI) and biological aging are critical drivers of cardiovascular disease (CVD). However, their joint pathogenic effects and underlying mechanisms in the development of CVD remain elusive. This study aims to investigate the independent and joint effects of BR...

Interaction ofFood-Derived Bitter Peptides with hTAS2R4:Recognition and Activation Mechanisms Revealed by Docking and Mutagenesis

Abstract Bitter peptides (BPs) have a wide range of applications in the food and pharmaceutical industries. This study identified four food-derived BPs (TPLVDR, VLY, LEEL, and FYL) as novel agonists of the human bitter taste receptor hTAS2R4, using a rapid cell-based screening ap...

Understanding Transversely Polarized Quarks Inside Longitudinally Polarized Nucleons

We review the current understanding of transversely polarized quarks inside longitudinally polarized nucleons from the perspective of the longi-transversity distribution function and transverse-momentum-dependent (TMD) factorization. Employing the recently developed TMD evolution...

Antioxidant nanozymes for regenerative medicine: mechanisms, design, and applications in tissue repair

Natural antioxidant enzymes play a central role in regulating oxidative stress within living organisms. During tissue repair following injury, these enzymes act synergistically to scavenge excess reactive oxygen species and maintain cellular redox homeostasis, thereby supporting...

The crystal structure of 10 H -phenothiazine-10-carbonyl chloride C 13 H 8 NOSCl

Abstract C 13 H 8 NOSCl, monoclinic, I 2/ a (no. 15), a = 12.7689(2) Å, b = 8.9005(1) Å, c = 20.9192(3) Å, β = 103.333(2)° V = 2313.35(6) Å 3 , Z = 8, R gt ( F ) = 0.0376, w R ref ( F 2 ) = 0.1040, T = 294.9(3) K.

Spatiotemporal-switchable 2D NIR-II single-atom nanozyme for single-cell–level surgical navigation and glioblastoma phototherapy

Single-cell–level resolution tumor therapy represents an advanced strategy against glioblastoma but lacks suitable theranostic agents. Here, we developed a spatiotemporal-switchable, two-dimensional (2D), bismuthene-based second near-infrared window (NIR-II) nanozyme. In this pla...

Deformation behavior of plastic-metal hybrid components for optical image stabilization: from injection molding to thermal processing

Abstract Micro-structured plastic-metal hybrid (MPMH) components fabricated by insert injection molding are widely used in miniaturized optical modules because of their structural integration and multifunctional performance. However, the multi-stage processes from injection moldi...

p38β-mediated BiP phosphorylation drives stemness and chemoresistance by suppressing UPR activation in hepatocellular carcinoma

Abstract Tumor-initiating cells (TICs) promote tumor initiation and therapy resistance, yet the kinase regulators that sustain TICs remain incompletely defined. Here, we identify the stress kinase p38β (MAPK11) supports TIC maintenance and drug resistance in hepatocellular carcin...

Au Single‐Atom Interlayer Bridge Promotes Cross‐Layer Charge Transport and Intrinsic Catalytic Dual‐Sites Activation for Efficient CO 2 Photoreduction

ABSTRACT Layered photocatalysts are attractive for artificial photosynthesis, but their performance is often limited by inefficient charge transport across interlayer gaps and sluggish surface reaction kinetics. Herein, we propose a single‐atom interlayer bridge strategy by intro...

Combined administration of fructooligosaccharides and Clostridium butyricum attenuates bowel cleansing-induced dysbiosis and safeguards mucosal defense in a murine model

Bowel preparation with polyethylene glycol electrolyte solution (PEG-ELS) is indispensable for gastrointestinal endoscopy and related procedures. However, it disrupts gut microbial homeostasis and increases host vulnerability to ensuing infection. In a murine model, we optimized...