Zhejiang University

Effect of transcutaneous auricular vagus nerve stimulation on postoperative gastrointestinal dysfunction in patients with gynecological abdominal or pelvic tumors: a study protocol for a prospective, single-center, randomized, controlled clinical trial

BACKGROUND: Postoperative gastrointestinal dysfunction (POGD) commonly presents with nausea, vomiting, abdominal distension, delayed flatus or stool, and prolonged intolerance to oral intake. It can cause postoperative pain, delayed gastrointestinal motility, or intestinal obstru...

Riding the catch-up cycle: how market maturity shapes local provision of ICT contracting in China

Although governments frequently employ public procurement to advance local economic development, buy-local objectives may conflict with the competition principle that underlies modern procurement systems. This tension may vary with market maturity, which shapes both supplier capa...

Breaking Barriers Toward Practicality: Critical Materials and Strategies for High‐Energy‐Density Aqueous Zinc‐Ion Batteries

ABSTRACT Driven by the demands of grid‐scale energy storage and the electrification of transport, achieving superior energy density is pivotal to establishing a more sustainable and economically resilient battery ecosystem. However, aqueous zinc‐ion batteries (ZIBs), despite thei...

User experiences and community responses to generative artificial intelligence health advice on reddit: topic modeling and content analysis study

Generative artificial intelligence (AI) chatbots are increasingly used for everyday health information seeking, yet little is known about how users interpret AI-generated health advice outside clinical encounters or how online communities respond when that advice is shared. This...

An expert-level generalist AI for abdominal CT diagnosis

Artificial intelligence (AI) in radiology aspires to deliver expert-level diagnosis across diverse clinical tasks, yet existing supervised strategies remain limited in scope. We developed RADAR, a generalist vision-language model trained on more than 400,000 contrast-enhanced abd...

Mechanical Behavior and Stability Analysis of Underground Excavation Construction: Case Study of Large-Span and Variable Cross-Section Subway Crossover Tunnel

This paper presents a case study on the deformation characteristics and stress evolution of a large-span variable cross-section crossover tunnel excavated by the mining method. Three construction alternatives are compared: Scheme 1 adopts staggered excavation of twin tunnels with...

Skeletal Distortion Manipulation in 2D–3D-Fused Boron Clusters Enables Solid-State Luminescence and Photothermal Conversion

Abstract Luminescent π-conjugated materials are central to modern optoelectronics, yet they are typically constructed from planar, rigid molecular frameworks. Herein, we introduce a conceptually distinct luminescent molecular platform based on three-dimensional (3D) boron cluster...

Large language models for literature screening in conceptually complex and interdisciplinary reviews

Purpose This study examines the capabilities and limitations of large language models (LLMs) for literature screening in systematic reviews involving conceptually diffuse and interdisciplinary topics. Design/methodology/approach Two screening datasets were constructed. Four LLMs,...

Structural Control of Phthalate Toxicity in Agricultural Soil Biofilms: Aliphatic-Chain-Length-Driven Hazards Revealed by Field Evidence, Multiomics, and Quantum Chemical Analysis

Abstract Phthalates (PAEs) pose significant ecological risks in greenhouse soils because of their hydrophobicity and persistence. This study combined field survey, microcosm experiments, multiomics analysis profiling, and quantum chemical calculations to investigate how the aliph...

What Contributes to Self‐Efficacy in Speaking Chinese as a Foreign Language: A Social Cognitive Perspective

ABSTRACT Grounded in social cognitive theory, this study investigated how high‐evidence factors jointly contribute to Chinese‐as‐a‐foreign‐language (CFL) speaking self‐efficacy. Data from 236 CFL learners in Beijing revealed a multifaceted pattern of associations. Speaking strate...

Protocol for designing and evaluating antibody-drug conjugates to promote endocytosis and lysosomal trafficking

Receptor endocytosis and lysosomal delivery are critical for efficient intracellular delivery of antibody-drug conjugates (ADCs), yet many cancer targets exhibit limited internalization. Here, we present a protocol for engineering and evaluating ADCs to induce receptor ubiquitina...

Spectral Matching and Spatially Dependent Polarization‐Selective Attenuation in Chiral Au‐SiO 2 ‐Quantum Dot Nanohybrids

ABSTRACT Discrete colloidal nanohybrids that combine efficient achiral emitters with chiral plasmonic nanostructures offer a promising route to solution‐processable circularly polarized luminescence (CPL)‐active materials. Here, we construct Au/SiO 2 /QDs nanohybrids by assemblin...

An Integrated Strategy for Decoding Bioactive Components and Mechanism of Jingtong Granules: Chemical Characterization, Network Analysis, Pharmacokinetic and Pharmacodynamic Studies

This study aimed to identify bioactive constituents of Jingtong Granules (JTG), a traditional Chinese medicine for cervical spondylotic radiculopathy (CSR), characterize their in vivo exposure, and explore pharmacological targets and pathways. Chemical constituents were character...

Clinical evaluation of deep learning-enhanced respiratory gated 18F-FDG PET/CT images

Abstract Objectives This study aims to comprehensively assess the value of deep learning (DL) models in improving the image quality of respiratory-gated PET/CT and explore the impact of PET acquisition time on the quality of model-predicted images. Methods We enrolled 90 patients...

An OsSK12/13‐OsERF60‐OsHsfA2c module regulates heat stress tolerance in rice

Heat stress severely impairs plant growth and limits crop productivity. GSK3-like family proteins regulate diverse cellular processes, including plant responses to abiotic and biotic stresses. Nevertheless, their specific functions in heat stress responses remain poorly character...

Toward scalable organ-level 3D plant segmentation: A systematic and quantitative review through the lens of the data-algorithm-computing triangle

The precise characterization of plant morphology provides valuable insights into plant-environment interactions and genetic evolution. A key technology for extracting this information is 3D segmentation, which delineates individual plant organs from complex point clouds. Despite...

Tension–Compression Fatigue Behaviour of Jacket Grouted Connections with Different Grout Strengths

Grouted connections are widely used in offshore jacket structures and are often subjected to eccentric compression and tension–compression cyclic loading arising from installation deviations and environmental actions. This study presents a comparative investigation of the fatigue...

Efficacy of hemodynamic profiling-guided antihypertensive therapy in elderly patients with early morning hypertension: a randomized controlled multicenter clinical study

Abstract Objective To evaluate the efficacy of hemodynamic profiling (HDpro)-guided antihypertensive therapy in elderly patients with uncontrolled morning hypertension. Methods A multicenter randomized controlled trial was conducted in 9 hospitals in Zhejiang Province, enrolling...

Elucidating Ionic Programming Thermodynamics of Oxide‐Ion‐Based Electrochemical Random‐Access Memory Devices

ABSTRACT Electrochemical random‐access memory (ECRAM) enables analog conductance modulation by tuning the carrier concentration in the channel, making it a promising hardware platform for neuromorphic computing. Consequently, elucidating the quantitative relationship between the...

MG53 suppresses IRF7 to reprogram macrophages and promote antitumor immunity in pancreatic ductal adenocarcinoma

In pancreatic ductal adenocarcinoma (PDAC), the desmoplastic stroma and immunosuppressive tumor microenvironment (TME) present barriers to immunotherapy. Here, we show that MG53 (TRIM72) is a critical regulator of macrophage fate and anti-tumor immunity; its myeloid-specific depl...