Xi'an Jiaotong University

Red nucleus contributes to the maintenance of neuropathic pain in male rats via CCL3-CCR5 axis

The latest evidence indicates that the red nucleus (RN) contributes not only to motor control, but also to sensory processing and emotion regulation. Here, we demonstrate that the RN participates in the maintenance of neuropathic pain via CCL3-CCR5 axis. Following spared nerve in...

Anti-nephrolithiatic Activity of Acacetin in Ethylene Glycol-Induced Nephrolithiasis in Rats

Nephrolithiasis, commonly known as kidney stones, is a prevalent urological disorder characterized by the accumulation of crystalline deposits in the kidneys. This condition is linked to considerable morbidity owing to the accompanying colicky pain, the necessity for surgical int...

Millimeter-thick microsupercapacitors with linear thickness-scaling of energy and power densities via multilayer electron highway architecture

The relentless miniaturization of microelectronics demands energy storage systems with ultrahigh energy and power densities in ultracompact footprints. Microsupercapacitors (MSCs) are promising due to their rapid charge-discharge capabilities, but conventional electrode architect...

Cellulose Tissue Separator With Aramid‐BaTiO 3 Composite Dielectric Coating Proactively Stabilizing Zinc Metal Anodes

ABSTRACT A fatal issue of zinc‐based electrochemical energy storage (ZEES) is uneven Zn 2+ deposition and rampant dendrite growth on the zinc metal anode, which significantly reduces the lifespan and reliability of ZEES devices. This work reports a cellulose tissue (CT) based sep...

ROS-Responsive, Water–Oil Biphasic Hydrogel-Based Separable Microneedle System for Intra-Articular Delivery in Osteoarthritis Therapy

Abstract Osteoarthritis (OA) is characterized by a chronic inflammatory microenvironment with excessive reactive oxygen species (ROS) and progressive cartilage degeneration. To address these challenges, we developed a ROS-responsive, water–oil biphasic separable microneedle patch...

Robust, Recyclable, and Reversibly Adhesive Polysulfide Elastomers via Inverse Vulcanization

Abstract Inverse vulcanization stands as a transformative strategy for valorizing surplus sulfur into polysulfides; however, inverse vulcanized polysulfides typically necessitate harsh synthetic conditions and suffer from an intrinsic trade-off between mechanical strength and net...

Real-Time Heat-Sink Capability Monitoring Framework of Fuel Thermal Management System

With the proliferation of high-power electronics, electric propulsion, and directed-energy weapons, thermal management has evolved from a high-speed flight concern into a systemic bottleneck across subsonic, transonic, and supersonic aircraft. Conventional fuel thermal management...

Demographic time bomb in COPD (1990–2050)

Chronic obstructive pulmonary disease (COPD) is a leading global cause of morbidity and mortality, characterized by irreversible airflow limitation and progressive symptoms. Despite declining age-standardized rates (ASRs), absolute burdens are rising due to population aging and g...

Halogen Substitution as a “Chirality Editor” for Amplifying Spin‐Selective Transport in Lead‐Free Metal‐Halide Hybrids

ABSTRACT Lead‐free metal‐halide hybrids hold promise as flexible semiconductors for X‐ray detection, but their application is constrained by inefficient carrier transport. Here, we introduce halogen substitution on chiral molecular cations as a “chirality editor” to modulate the...

Halogen Substitution as a “Chirality Editor” for Amplifying Spin‐Selective Transport in Lead‐Free Metal‐Halide Hybrids

ABSTRACT Lead‐free metal‐halide hybrids hold promise as flexible semiconductors for X‐ray detection, but their application is constrained by inefficient carrier transport. Here, we introduce halogen substitution on chiral molecular cations as a “chirality editor” to modulate the...

Assessment of Terrestrial Carbon Sinks: A Review of Methodological and Framework Limitations and Future Prospects

Ecosystem carbon sinks are a key indicator of terrestrial ecosystems' ability to absorb and store atmospheric CO₂. Their accurate assessment is of great significance for addressing global climate change and achieving carbon reduction targets. Due to limitations in the timeliness...

Transient Power-Angle Stability Analysis of Grid-Forming Energy Storage in Renewable Energy Stations Connected to a Remote Power Grid

The increasing penetration of renewable energy has made the transient stability of new power systems a critical concern. Grid-forming (GFM) energy storage can provide voltage and frequency support for renewable energy stations. However, existing studies on the transient stability...

Cumulative body mass index burden from childhood to mid-adulthood in relation to subclinical cardiovascular outcomes: The potential mediating role of cardiovascular risk factors

The associations of long-term body mass index (BMI) exposure, including both cumulative burden and increasing trends from childhood to adulthood, with subclinical cardiovascular outcomes remain incompletely understood, especially across distinct life stages. This study aimed to e...

Determinants of life expectancy with unmet needs in the Chinese older population (revision 1)

Abstract This study investigates the determinants of and disparities in life expectancy (LE) with unmet long-term care needs among older people in China. The data come from four waves of the China Health and Retirement Longitudinal Study (CHARLS), a nationally representative surv...

Glucagon-like peptide 1 receptor agonists in cardiovascular-kidney-metabolic syndrome: a review

With the rising global prevalence of obesity and type 2 diabetes, metabolic disorders have become major drivers of cardiovascular morbidity and mortality worldwide. Cardiovascular-kidney-metabolic (CKM) syndrome encompasses obesity, type 2 diabetes mellitus (T2DM), chronic kidney...

Multimodal synthesis of neural correlates of motor imagery after spinal cord injury: a systematic review

Spinal cord injury (SCI) profoundly disrupts motor output while also reshaping central motor systems. Motor imagery (MI) provides a valuable window into retained motor-related neural processes because it enables investigation of covert motor state generation in the absence of ove...

Enjoyment and Engagement in AI ‐Mediated Informal Digital Learning of English: A Latent Growth Curve Modelling Study

ABSTRACT Enjoyment and engagement are critical for effective language learning, yet little is known about how these experiences evolve over time in AI‐mediated informal digital English learning (IDLE). Previous studies have mainly relied on cross‐sectional designs, limiting under...

Finite time blow-up and global solutions for the viscoelastic wave equation with combined power-type nonlinearities

The main objective of this paper is to investigate the global existence and nonexistence of solutions to the viscoelastic wave equation with a linear memory term of Boltzmann type, a nonlinear friction damping and a supercritical source term which is a combination of power-type n...

A tumor microenvironment acid-responsive therapy combining fenton chemistry and chemotherapy via TNF pathway for synergistic and safe lung cancer treatment

Lung cancer is one of the most common malignant tumors, but traditional treatments, particularly chemotherapy, often face significant challenges, including drug resistance and high systemic toxicity. In this study, we developed a novel acid responsive nanoparticle, La₂O₃@PDA/PTX,...

Trade-Offs Among Arc Erosion Resistance, Wear Resistance, and Compressive Performance: Designing Cu-Nb-Gr Composites with a Semi-Continuous Gr-Rich Structure Coupled with an Nb-Rich Load-Bearing Structure

Developing Cu-based composites with excellent electrical and mechanical properties under multiphysics-coupled service conditions remains challenging. Novel Cu-Nb-Gr composites were fabricated by high-energy ball milling and High-pressure Multi-field Assisted Rapid Sintering. Expe...