Westlake University

Potential structure induced effects of the hairpin motif in RNA to form the phase separated droplet like associate in different solution condition

Reversible associations of RNAs among themselves, or with RNA binding proteins through the process of phase separation, are found to be important in many different cellular contexts, including cellular responses to stress, gene regulation, development, and disease. Short RNA repe...

Sustainable ammonia synthesis from nitrate wastewater via graphdiyne Mo–Cu–C≡C interfaces

Electrochemical green ammonia (NH3) production using renewable electricity is sustainable but suffers from selectivity-activity-stability trade-off under industrial conditions. Here we report an atomic interface engineering strategy enabling in-situ assembly and coupling of hexae...

Longitudinal dynamics of the maternal gut virome associate with metabolic features of preterm birth

Preterm birth (PTB) remains a major pregnancy complication, yet the role of the maternal gut virome in its etiology is largely unknown. Here we show that the maternal gut virome undergoes ecological destabilization prior to PTB, coupled with distinct host metabolic remodeling. Ne...

How well can off-the-shelf LLMs elucidate molecular structures from mass spectra using chain-of-thought reasoning?

Mass spectrometry (MS) is a powerful analytical technique for identifying small molecules, yet determining complete molecular structures directly from tandem mass spectra (MS/MS) remains a long-standing challenge due to complex fragmentation patterns and the vast diversity of che...