UNSW Sydney

Computationally Evidence‐Grounded Sequence‐First Design of Peptide Binders

Peptide binders provide a versatile modality for modulating protein targets that are poorly addressed by small molecules, but their discovery is constrained by sample-intensive screening or reliance on structural templates. Sequence-first generation offers a scalable alternative...

Mapping structural heterogeneity in three-dimensional biophotonic gyroid networks using position-resolved small-angle X-ray scattering

Abstract The wings of select Papilionid and Lycaenid butterflies contain a three-dimensional gyroid network of a solid cuticle phase in air. In butterfly scales, gyroid networks are optically interesting, as they create the green colour observed in the wings of these butterflies....

Chemovaccination with a late-liver-stage antimalarial induces durable immunity against malaria

Plasmodium falciparum sporozoite vaccines, in which parasites are attenuated at the liver stage, provide high efficacy but require complex manufacture and intravenous administration of high sporozoite doses. We found that a single low-dose P. berghei sporozoite exposure (intraven...

SDMBCv2 (v1.0): correcting systematic biases in RCM inputs for future projection

Abstract. Regional Climate Models (RCMs) offer enhanced spatial resolution and a more realistic depiction of local climate processes. However, they often inherit systematic biases from their driving Global Climate Models (GCMs), which can compromise the accuracy of downscaled cli...

More than just temperature: the effects of nest relocation on incubation environment and hatchling quality in green turtles (Chelonia mydas)

Abstract Nest relocation and shading are widely used conservation strategies intended to mitigate threats to marine turtle hatchling survival. However, these interventions may carry unintended fitness costs. Estimating such effects can be challenging, especially in the absence of...

Genomic catalogue of giant viruses reveals expanded diversity and functional potential

Nucleocytoplasmic large DNA and Mirusviricota viruses exhibit taxonomic richness which continually expands due to metagenomic sequencing. Here we curate a database of giant virus metagenome-assembled genomes (GVMAGs V2), comprising 8,508 species-level representatives from 18,727...

Exploring the financial resilience of REITs across three crises

Purpose This study examines the static and dynamic resilience of REITs in Australia, Singapore, France, Italy, Germany, the United Kingdom, Canada and the United States during three major global events – the September 11 attacks in the US, the Global Financial Crisis (GFC) and th...

Se4+-Doped Indium-Based Perovskites via NaCl-Driven Structural Transformation for Dynamic Luminescence Modulation in Multimodal Anti-counterfeiting and Encryption

Abstract The growing risks of counterfeiting and information security breaches have spurred the demand for high-security stimuli-responsive optical materials. However, many reported materials exhibit discontinuous luminescence switching or require harsh external stimuli. Herein,...

John Stewart Turner

Abstract Black and white portrait showing John Stewart Turner, an older man with a receding hairline, wearing thick-framed glasses, a light-colored textured suit jacket, a white shirt, and a light-colored tie with a dotted pattern. He smiles slightly and looks directly forward. B...

Everyday journeys, everyday risks: examining adolescent road safety knowledge, practices and perceptions in Delhi, India

Background Adolescents represent a high-risk group for road traffic injuries, particularly in rapidly motorising cities in India. This study aimed to document the travel patterns and understand the road safety knowledge, practices and safety perceptions of adolescents during thei...

Prevalence and Determinants of Sexually Transmitted Infections Among Thai Men Who Have Sex with Men Enrolled in National Pre-Exposure Prophylaxis Program: A Real-World Cross-sectional Study

Background: Sexually transmitted infections (STIs) remain a major public health concern among men who have sex with men (MSM). This study estimated STI prevalence and associated factors among MSM enrolled in Thailand’s national pre-exposure prophylaxis (PrEP) registry under the U...

Multifactorial ecological framework for intestinal-type gastric cancer

Gastric cancer (GC) remains one of the leading causes of cancer-related mortality worldwide, with projections indicating increasing incidence and marked geographic variability across populations. Although multiple hypotheses have been proposed to explain this heterogeneity, inclu...

Why Are Cascade Birth Interventions Rising?

The increasing use of birth interventions has prompted global policy and research focus. This study attempts to enhance our understanding of why this increase is occurring. Using a population-based dataset of over 1.3 million births in New South Wales, Australia (2004–2018), we i...

Optimizing Informed Consent for Australian Newborn Bloodspot Screening and Research: Consensus Workshop Insights and Recommendations

Informed consent is fundamental to Australian newborn bloodspot screening (NBS), but emerging genomic screening technologies pose new challenges to clinical care and research. Optimizing consent processes is necessary to support ethical practice and maintain public trust as NBS e...

Does TikTok promote or cannibalize music streaming? Estimands and identification with heavy-tailed outcomes

Abstract We study how TikTok affects demand for music on paid streaming platforms in the context of Universal Music Group’s (UMG) global withdrawal of its catalog from TikTok. Recent studies using this quasi-natural experiment have reached different conclusions about whether TikT...

A Stock Market Price Prediction Model Integrating a CNN–Transformer Dual-Channel Dynamic Attention Architecture

Stock market price prediction remains a persistent challenge owing to the non-stationarity, high noise content, and intricate spatiotemporal dependencies that characterize financial time series. Existing approaches typically excel at either local pattern extraction or long-range...

Maximising the ‘co’ in co-design through facilitator actions: co-designers’ perspectives on what makes their participation in co-design meaningful

Co-design is a participatory approach to service development and research that is increasingly expected within the mental health sector. It involves end users being involved throughout a design process, not simply by providing opinions, but through shared decision making. Evidenc...

Effects of Morning and Evening Narrowband Blue Light and Myopic Defocus on Axial Length in Humans

Purpose To investigate the effects of morning and evening narrowband blue light exposure on axial length, and to examine the short-term effect of morning blue light combined with myopic defocus on axial length.Methods For objective 1, 18 individuals underwent 60 minutes of narrow...

Gender-affirming psychiatry: a minority stress and phenomenological framework for child and adolescent mental health

This perspective article introduces Gender Affirming Psychiatry (GAP), a conceptual framework that integrates queer phenomenology, the gender minority stress model, and gender-affirming care to guide psychiatric assessment, formulation, and treatment of transgender and gender div...

Health Care Stigma and HIV/Sexually Transmitted Infection Prevention Service Uptake Among Cisgender Men and Gender-Diverse Individuals Who Have Sex with Men in Five Asian Countries: Implications for Differentiated Service Delivery

Health care stigma remains a key barrier to HIV and sexually transmitted infection (STI) prevention, yet its effects may differ across health care systems. We examined associations between health care stigma and HIV/STI prevention service uptake across five Asian countries. A cro...