University of Utah

Financial Hardship and Household Food Insecurity During the COVID-19 Pandemic: Evidence From the Panel Study of Income Dynamics

Purpose Research has documented changes in food insecurity (FI) in the U.S. during COVID-19, including initial spikes and widening inequities followed by eventual declines. Yet a lack of representative longitudinal data has limited efforts to examine FI trajectories. Design We us...

Implications of Missing Data Mechanisms in Randomized Controlled Trials: Current Practices and Suggestions Utilizing the ACTIVE Study

ABSTRACT Background Missingness in randomized controlled trials (RCTs) might mask or inflate effects with consequences for translating results confidently. The current study presents three steps to establishing confidence in results in light of missing data using an RCT examining...

Identificationand Validation of a Novel WNK2 Inhibitor:A New Genetically Informed Target for Osteoarthritis Drug Development

Abstract Osteoarthritis (OA) is a disease characterized by loss of joint space, degeneration of cartilage at articular surfaces, remodeling of bone and other joint tissues, low-grade inflammation, and pain. It is a leading cause of disability in the aging population. We do not ha...

Telemedicine Use in Primary Care for Children: 2019–2024

BACKGROUND AND OBJECTIVES We lack national data on the maturing clinical use of telemedicine (TM) in children’s primary care. This manuscript describes patterns of TM use for problem-based visits overall, across clinical domains, and associations of use with clinic visit volume....

Climate Anxiety Among Undergraduates at an R1 University in the United States

Climate anxiety is an emerging public health concern, particularly among young adults. Using survey data, this study examines the prevalence, emotional dimensions, and predictors of climate anxiety among 547 undergraduate students at a large university in the U.S. Mountain West....

Recent lifestyle change impacts sleep and circadian rhythms among the Indigenous peoples of Peninsular Malaysia

ABSTRACT Sleep disorders are rising globally, but their lifestyle causes remain unclear. We recorded sleep-wake patterns via actigraphy from 1036 Orang Asli adults across 12 communities in Peninsular Malaysia undergoing market integration, marked by changes in permanent infrastru...

Long‐term prediction of epilepsy following traumatic brain injury among veterans using routine clinical data

OBJECTIVE: Despite elevated risk for epilepsy following traumatic brain injury (TBI), there are limited tools to assess epilepsy risk following TBI using routine clinical data. The objective of this study was to develop and validate a machine learning approach to predict the onse...

The Impact of Septorhinoplasty on Work Productivity and Activity Impairment: A Multi‐Institutional, Prospective Cohort

OBJECTIVE: To evaluate the effect of septorhinoplasty on work productivity and activity impairment. STUDY DESIGN: Prospective cohort. SETTING: Four tertiary institutions. METHODS: Adults undergoing septorhinoplasty were administered surveys preoperatively and 3 to 8 months postop...

Ruling In and Ruling Out Sepsis Using Likelihood Ratios of a Host Response Assay

Overview: SeptiCyte RAPID is an FDA-cleared gene expression test that quantifies host immune response to aid in the diagnosis of sepsis. The test yields a score (the SeptiScore) ranging from 0–15, distributed across four bands (1–4) based on increased likelihood of sepsis. Each b...

Surgical Management of Young Women with High-Risk Breast Cancer Receiving Neoadjuvant Systemic Therapy on the I-SPY2 Trial

BACKGROUND: Mastectomy rates in women with breast cancer are higher in younger women than in older women. The impact of this more extensive surgery on overall survival (OS) and locoregional recurrence in younger women is unknown, especially after neoadjuvant systemic therapy (NST...

“An Enrollment Opportunity That’s Aligned with Who We Are” A Critical Analysis of Campus Presidents Supporting Prison Education During Targeted Incarceration

This qualitative study draws upon semi-structured interviews with 31 college and university presidents whose institutions host prison education programs. We examine how presidents justify their support for prison education and find three dominant themes among their narratives: mi...

The Mo, Tl, and U isotope paleoredox proxies: comparisons, contrasts, and future directions

Sedimentary molybdenum (Mo), thallium (Tl), and uranium (U) isotope ratios can potentially track global-scale changes to past ocean oxygenation levels. In this review we summarize and describe the unique strengths and weaknesses of these “paleoredox proxies”. We emphasize two cri...

Cost‐Effectiveness of Radiofrequency Ablation for Benign Non‐Functioning Thyroid Nodules: A Systematic Review

ABSTRACT Purpose This systematic review tests the hypothesis that radiofrequency ablation (RFA) for benign non‐functioning thyroid nodules is associated with favourable cost‐effectiveness compared with surgery. Materials and Methods A systematic literature search of multiple data...

Availability and Quality of Electronic Health Record Data to Track Physical Function Across a Care Transition

ABSTRACT Introduction Physical function (PF) is critical to quality of life and healthcare value, especially for older adults following hospitalization. Monitoring PF supports recovery, reduces adverse events, and improves care transitions. Despite the potential of electronic hea...

Implementation strategies and adjunctive interventions for HIV testing and linkage-to-care in the United States: a systematic review

Ending the HIV Epidemic in the United States depends on expanding HIV testing and rapidly linking people to care. However, methods to improve testing and linkage-to-care are inconsistently described and often conflate health system–level implementation strategies with recipient-d...