University of Turin

Outcomes and adverse events of postoperative stereotactic interventional radiotherapy/brachytherapy for brain metastases: a systematic review

Postoperative radiotherapy is commonly used after resection of brain metastases, but durable local control with a low rate of adverse events (AEs) remains challenging. This systematic review summarizes outcomes and AEs of postoperative stereotactic interventional radiotherapy (S-...

“Uroboros” circle: a multilevel study on leader–follower and follower–leader crossover

Purpose The literature on the crossover theory (Westman, 2001) typically focuses on how leaders influence followers’ well-being by exchanging psychological states and resources (Hobfoll et al., 2018). However, the role of followers in influencing leaders’ well-being has been less...

Adaptive response to serine and glycine deprivation enhances the stemness potential of pancreatic cancer cells

Pancreatic ductal adenocarcinoma (PDAC) develops within a nutrient-poor microenvironment, where pancreatic cancer stem cells (PaCSCs) can persist despite limited oxygen and nutrient availability. This resilience partially relies on mitochondrial metabolic flexibility. Serine and...

Detecting emotional distress in cancer patients through sentiment analysis

Cancer patients often experience profound emotional distress throughout diagnosis, treatment, recurrence, and survivorship. Feelings of fear, sadness, uncertainty, and psychological burden frequently appear in cancer-related narratives, and these emotional challenges also extend...

Feasibility of Using Digital Clinical Records to Identify Factors Associated with Nursing-Sensitive Outcomes During Hospitalization: A Pilot Study

Background/Objectives: Nursing-sensitive outcomes are key indicators of nursing care quality and safety. Digitalization of clinical documentation enables prospective surveillance using routine data, but real-world evidence on integrated digital, clinical record-based approaches r...

Molecular surveillance of tick-borne pathogens in wild mammals from Poland: host-specific patterns of Babesia spp. and Anaplasma phagocytophilum

Abstract Tick-borne diseases are increasingly threatening human and animal health in Europe, yet molecular data from wild mammals in Poland remain limited. This study investigated the prevalence of selected tick-borne pathogens in large wild mammals from Poland. Spleen samples fr...

Zoonotic Sarcocystis hominis and Sarcocystis heydorni in a Bovine Carcass: First Report in Portugal

During routine meat inspection, eosinophilic myositis-like lesions were detected in the masseter muscles of a 55-month-old bovine, leading to partial condemnation of the head. The lesions appeared as multiple round, yellowish-green areas, suggestive of a parasitic aetiology. Hist...

Modeling Diabetic Neuropathy: Injury Biomarkers for Early Detection Through Neuronal and Glial In Vitro Models

Diabetes mellitus (DM) is a rapidly expanding global health burden and a leading cause of chronic complications. Among these, diabetic peripheral neuropathy (DN) is one of the most prevalent and disabling, affecting up to half of individuals with long-standing diabetes and involv...

Osteitis Pubis in Athletes in the Era of Pubic-Related Groin Pain: Contemporary Concepts in Diagnosis, Rehabilitation, and Surgical Decision-Making

Background: Osteitis pubis (OP) is a recognized contributor of anterior pelvic and groin pain, particularly in athletic populations, and is currently included within the wider spectrum of pubic-related groin pain. Despite the growing body of literature, clinical management is sti...

Top-Degree global solvability for tube complexes in gevrey ultradistributions

Abstract Let $$s>1$$ s > 1 , let $$M$$ M be a connected, non-compact, oriented real-analytic manifold, and let $$\omega _1,\ldots ,\omega _m$$ ω 1 , … , ω m be real-valued closed 1-forms of Gevrey order s on M . We study the differential complex naturally associated with this fam...

Multilevel narrative assessment in children with early cochlear implants compared to typically hearing peers

Cochlear implants (CIs) provide auditory access that supports the development of oral language in deaf children with severe-to-profound hearing loss, especially when implantation occurs early. This study assessed narrative abilities in 16 school-aged children with early CIs compa...

Pneumococcal population structure influences the effects of air pollution on invasive disease risk in South Africa

Abstract Streptococcus pneumoniae is highly diverse, comprising over 100 serotypes and hundreds of genomic lineages amid widespread vaccination. While it can cause invasive pneumococcal disease (IPD) which exhibits pronounced seasonal spikes, the interplay between pneumococcal di...

Circulating tumor DNA-guided de-escalation or escalation of adjuvant therapy in high-risk stage II and stage III colon cancer: the phase 2 PEGASUS trial

Oxaliplatin–fluoropyrimidine combinations are standard adjuvant therapy after radical resection of high-risk stage II and stage III colon cancer but expose many patients to toxicity while failing to prevent relapse in others. PEGASUS was a multicenter, single-arm, phase 2 trial e...

The effect of different hemostatic agents on hemorrhage control, pain and quality of life after endodontic microsurgery

This randomized clinical trial evaluated the effect of two different hemostatic materials for endodontic microsurgery on bleeding control, postoperative pain and patients’ quality of life. Thirty-four subjects with apical periodontitis requiring endodontic microsurgery were rando...

Longitudinal health-related quality of life after electrochemotherapy in elderly patients with cutaneous melanoma

The incidence of cutaneous melanoma (CM) is increasing among elderly patients, who often present with advanced disease, including cutaneous metastases. Electrochemotherapy (ECT) is a local ablative treatment that enhances chemotherapy uptake via electric pulses. Management in pat...

Assessing glymphatic role in the association between choroid plexus enlargement and white matter lesions load: The uncertain path through diffusion tensor imaging along the perivascular space (DTI-ALPS)

Background The choroid plexus (CP) is involved in cerebrospinal fluid production, immune surveillance, and brain fluid homeostasis. CP enlargement has been linked to neuroinflammation, glymphatic dysfunction, and white matter lesion (WML) burden, but the mechanisms underlying the...

Quenching Kinetics of Triplet-State Photosensitizers in Environmental Photochemistry

Abstract Triplet-state photosensitizers (3Sens*) are central to carbon cycling and pollutant degradation in sunlit surface and atmospheric waters, but their environmental roles remain only partly understood. Although the photophysical and photochemical properties of 3Sens* have b...

Employees at risk within the “absent presence” paradox: a longitudinal comparison from non-smart to smart-working reward system in the Italian private/public sector

Purpose This contribution explores the evolution of employee motivation as a strategic asset in organisations. The objective is to investigate how the value of reward systems (monetary vs non-monetary) is changing in the era of the Smart Working Model (SWM), the paradoxes of the...

REE-depleted anatectic marble reveals the primary source of crustal carbonatites

Crustal-derived carbonatitic melts are increasingly recognised in high-grade terrains, but their residual source rocks remain largely unexplored. As a result, the crustal origin of carbonatites is generally constrained from geochemical signatures of the crystallised melts without...

Management of Acute Periodontal Conditions—The EFP S2k Level Clinical Practice Guideline

BACKGROUND: The European Federation of Periodontology (EFP) has developed Clinical Practice Guidelines (CPGs) for the treatment of periodontitis and for the management of peri-implant diseases. In accordance with the 2018 Classification, acute periodontal conditions are character...