University of Padua

Minimally invasive surgery for locally advanced colon cancer (pT4): short-term outcomes from a consecutive real-world cohort

Abstract Background The role of minimally invasive surgery (MIS) in pathological T4 colon cancer remains controversial because of the technical complexity of multivisceral resections and concerns regarding oncological adequacy. This study aimed to compare short-term postoperative...

Upcycling Spent LiCoO 2 Cathodes via Surface Spinel Reconstruction for Efficient Furfural Hydrogenation

Spent lithium‐ion batteries represent a growing environmental challenge, yet their transition‐metal‐rich cathodes remain largely underutilized as functional materials. We report a direct upcycling strategy in which LiCoO 2 cathodes recovered from end‐of‐life smartphones are trans...

Economic Inequality is Masculine: High Vertical Pay Gap Fuels Expectations for Gender Discrimination via Inferred Masculinity Norms

Gender discrimination remains a major obstacle to workplace equality. While various factors contribute to this issue, organizational structures that reinforce hierarchical, male-dominated cultures may indicate that gender discrimination is widespread and normative. This research...

Assessing the Climate and Habitability of Tidally Locked Rocky Exoplanets

Tidally locked exoplanets orbiting M dwarf stars are prime targets in the search for habitable worlds, yet their complex climate dynamics challenge conventional models of habitability. We homogeneously estimated the liquid–water habitability of exoplanets with the highest up-to-d...

Robotic Kidney Transplantation With Grafts With Multiple Arteries: A Single-center Experience and Outcome Analysis

Background. Although robotic kidney transplantation (RKT) is an emerging minimally invasive surgical technique, graft anatomical variations such as multiple renal arteries (MRAs) remain a perceived limitation to its broader dissemination. This study evaluates the feasibility and...

Sex-based differences in glycaemic variability and clinical outcomes among older inpatients with type 2 diabetes: insights from the GLIMPACT study

<title>Abstract</title> Methods A retrospective study of patients with type 2 diabetes aged 65 or older, admitted to the Geriatrics Unit of Padua University Hospital between January 2018 and December 2020. We recorded sociodemographic data, blood tests, multidimensional geriatric...

TSPO: a conserved mitochondrial conduit linking cellular homeostasis to disease

Abstract The translocator protein (TSPO) is an evolutionarily conserved 18 kDa protein localised to the outer mitochondrial membrane and increasingly recognised as a multifunctional regulator of cellular homeostasis. Although initially identified as the peripheral benzodiazepine...

VIA1 is a conserved regulator of thylakoid membrane integrity that acts through VIPP1

Abstract Thylakoid membranes are indispensable for oxygenic photosynthesis, yet the mechanisms that protect these membranes from photooxidative damage remain poorly understood. By screening previously uncharacterized proteins induced during the chloroplast unfolded protein respon...

Redox‐Confined Interfacial Polymerization Enables Mechanically Robust and Self‐Adhesive Nanofilms

ABSTRACT Robust polymer nanofilms are increasingly important for applications that require mechanically strong yet compliant membranes with nanoscale thickness and intimate interfacial contact. While biological membranes naturally combine flexibility, adaptability, and adhesion,...

Optimisation and Application of Kinetic Piezoelectric Energy Harvesters Aimed at Powering Autonomous Sensors

Piezoelectric energy harvesters, characterised by design simplicity, robustness, high energy density and conversion efficiency, as well as scalability, are a viable choice for transducing ubiquitous kinetic energy in a reliable and stable electrical energy source aimed at powerin...

Elevated IL-10 is Linked With the Expansion of T-bethighCD21low B Cells in Patients With Common Variable Immunodeficiency

Abstract Common variable immunodeficiency (CVID) is frequently complicated by autoimmune and inflammatory manifestations associated with profound immune dysregulation (CVIDc), including expansion of T-bet high CD21 low B cells (CD21 low B cells). Elevated serum IL-10 levels have...

SABER: a multiparental tomato population leveraging wild relative diversity for high-resolution QTL mapping

Abstract The narrow genetic base of cultivated tomato ( Solanum lycopersicum L.) represents a major constraint on crop improvement, necessitating the exploitation of wild relatives to broaden allelic diversity. Here we present SABER ( Solanum lycopersicum Allele Biodiversity Enri...

Triple potentiator combinations increase the functional correction of several CFTR gating mutants

The Trikafta drug combination, comprising the corrector tezacaftor (VX-661), the potentiator ivacaftor (VX-770) and the dual corrector/potentiator elexacaftor (VX-445), has been FDA-approved for treatment of cystic fibrosis caused by ~300 cystic fibrosis transmembrane conductance...

Characterizationof Airborne Emissions and PreliminaryIn Vitro Toxicity Screening of Polyamide 12 Used in Additive Manufacturing

Abstract Polyamide 12 (PA12) is a widely employed feedstock material in industrial additive manufacturing (AM) technologies. Despite this, there is limited epidemiological evidence regarding its health effects, raising particular concern about the potential implications for worke...

Assessing inter-model agreement in convection-permitting simulations of extreme winds for wind energy applications

Abstract. Convection-permitting models (CPMs) have great potential for wind energy applications such as wind energy planning, turbine design loads, and operational safety in a climate change context. In fact, compared to coarse-resolution models, they have an improved representat...

Bimodal multiphoton catalysis via structural regeneration

Abstract Most of the current photocatalytic methodologies for the generation of reactive radical intermediates have limited redox windows and can operate within a single redox manifold. Here, to overcome these constraints, we report a purely organic photocatalyst that operates vi...

Acute kidney injury and renal replacement therapy: a critical synthesis of metabolic derangements and nutritional implications

Acute kidney injury (AKI) affects up to 50% of critically ill patients and is frequently complicated by severe metabolic derangements, requiring the initiation of replacement therapy (RRT) in 10–15% of cases. Despite substantial progress in the diagnosis of AKI and optimisation o...

Local minimality of the truncated octahedron for the isoperimetric problem on parallelohedra

Abstract We investigate the isoperimetric problem for the Voronoi cells of three-dimensional lattices. Using Selling parameters, we derive an explicit closed formula for the scale-invariant isoperimetric quotient F in terms of six non-negative variables. We then analyse the local...

Feeding and Husbandry Practices in Pet Ferrets ( Mustela putorius furo ): A Cross‐Sectional International Study

ABSTRACT Background The domestic ferret ( Mustela putorius furo ) is an increasingly popular non‐traditional companion animal; however, limited information is available on how caregivers manage feeding and husbandry practices. Objectives This study aimed to investigate feeding an...

Transforming the treatment of autoimmune skin diseases: a journey through biologic therapies

INTRODUCTION Autoimmune blistering diseases and autoimmune connective tissue diseases with prominent skin involvement are increasingly managed with biologic and targeted therapies. We review the evidence supporting these approaches and their practical positioning.AREAS covered We...