Institution
University of Nottingham
Recent research
- Health & MedicineOpen access
Purpose: The purpose of this study is to evaluate anatomical, visual, and safety outcomes after repeat pars plana vitrectomy combined with 360° encircling scleral buckling for first recurrent rhegmatogenous retinal detachment following primary vitrectomy. Methods: This retrospect...
- Health & MedicineOpen access
The Hendra virus (HeV; Henipavirus hendraense) and Nipah virus (NiV; Henipavirus nipahense), members of the genus Henipavirus, are high-consequence pathogens that have caused multiple zoonotic outbreaks with high mortality. Frequently, pigs or horses have acted as bridging hosts...
- Health & MedicineOpen access
Abstract Artificial intelligence (AI) is rapidly transforming histopathology, with applications ranging from workflow optimisation and quality assurance to tumour diagnosis, grading, biomarker assessment and estimation of prognosis. While numerous AI algorithms have demonstrated...
- Society & EconomicsOpen access
Development and validation of the personal recovery scale (ReConnect) for mental health in Ethiopia
Background: Socio-cultural context is crucial for conceptualising personal recovery in mental health, but existing measures are from Western, high-income countries. Aim: To develop and validate a mental health personal recovery measure for people with mental health conditions in...
- Society & EconomicsOpen access
Re-electing the party leader: The 2024 PASOK contest
This article examines leadership contests in European mainstream parties confronting electoral decline and attempting to restore competitiveness. Focusing on this broader phenomenon, it analyses incumbent leaders seeking renewed mandates through open primary elections in such con...
- Engineering & TechnologyOpen access
Enabling alloy screening via multi-material printing using a production PBF-LB machine
The development of novel functional alloys is often constrained by the onerous and costly discovery to validation process. Herein, we present a set-up to enable multi-material production of specimens through in-situ alloy formation using a production laser-based powder bed fusion...
- BiologyOpen access
Progressive oxygenation of developing leaves directs morphogenesis
Abstract Oxygen availability underpins energy production in multicellular organisms, yet internal oxygen gradients arise in both plants and animals. Plants sense these variations via the PLANT CYSTEINE OXIDASE branch of the N-degron pathway, which regulates the stability of key t...
- BiologyOpen access
The third-generation antipsychotic cariprazine is a low-efficacy partial agonist of the dopamine D 3 receptor (D 3 R). Here, we report the cryo–electron microscopy structure of cariprazine bound to D 3 R, establishing a framework for understanding ligand recognition in this recep...
- Climate & EnvironmentOpen access
Distinct gut viral communities across life stages in dairy cattle
Abstract Background Ruminant gut microbial communities influence host health, productivity, and methane emissions, yet viral communities across life stages remain uncharacterized. Whilst bacteriophages shape microbial communities in many ecosystems, their role across dairy cattle...
- Engineering & TechnologyOpen access
Abstract Finite Element (FE) simulation of impact damage in fibre-reinforced composite laminates is constrained by high computational cost, many difficult-to-calibrate material parameters and the absence of experimental evidence for different composite structures. Artificial Inte...
- BiologyOpen access
Preparing to keep chickens: Your guide to safe housing, disease prevention and chicken welfare
This guide is targeted at people who keep poultry as a hobby or as pets. It provides suggestions on creating a safe setup for poultry and protecting them from predators, pests and disease.
- Biology
Abstract Introduction Glioblastoma is an aggressive brain tumour that, despite multimodal treatment, almost always recurs. Infiltrative tumour cells within the brain microenvironment are thought to drive recurrence and are supported by surrounding non-cancerous brain cells. Among...
- Health & Medicine
Summary Primary mediastinal B‐cell lymphoma (PMBCL) is a distinct clinicopathological entity within the spectrum of aggressive B‐cell lymphomas, characterised by unique clinical, immunophenotypic and molecular features. Since publication of the 2019 British Society for Haematolog...
- Society & Economics
The ‘legging up’ burden: Hidden struggles of model minorities in racialized mentoring at work
Drawing on contemporaneous microstoria narrated by Black model minorities (BMMs), this paper theorizes the legging up burden: the implicit expectation that BMMs, positioned as token representatives of their race, will provide mentoring and support to organizational members with w...
- Health & MedicineOpen access
Abstract Rare paediatric central nervous system (CNS) tumours comprise a biologically-heterogeneous group of low-incidence diseases that present significant challenges to both therapeutic development and clinical research, limiting the availability of high-quality evidence to gui...
- Health & MedicineOpen access
Abstract Background Neurodivergent children and young people, including those with autism, attention-deficit/hyperactivity disorder and intellectual disability, experience higher rates of mental health difficulties than their neurotypical peers. Despite this increased need, many...
- Health & Medicine
Abstract Topic Esophageal Cancer: Surgical Treatment of Esophageal Cancer – early outcomes and complications Background Outcomes after oesophago-gastric cancer surgery have improved over the last two decades, but it is unclear whether this reflects fewer complications, improved s...
- Health & Medicine
Abstract Topic Esophageal Cancer: Surgical Treatment of Esophageal Cancer – early outcomes and complications Background Outcomes after oesophago-gastric cancer surgery have improved over time, and this is likely to be multifactorial. In addition to better oncologic treatments, sa...
- BiologyOpen access
BACKGROUND: Kidney transplant rejection remains a leading cause of graft loss, and diagnosis still depends largely on invasive biopsies. Urinary extracellular vesicles (uEVs) offer a potential noninvasive alternative for detecting allograft rejection through molecular profiling o...
- Society & EconomicsOpen access
Languages and Concepts of European Civil Wars, 1917–39: An Introduction
Abstract This introduction opens a special issue on ‘Languages and Concepts of European Civil Wars, 1917–39’. Drawing on case studies of Russia, Finland, Ireland, Austria and Spain, the issue examines civil war as a struggle over language and political identity. Its articles cons...